Efficacy of an herbal preparation based on lovage, rosemary, and centaury on patients after extracorporal shockwave lithotripsy

Abstract

Study objective To study the effect of a herbal preparation containing a standardised BNO 1040 extract* (based on lovage root, rosemary leaves and aerial parts of centaury) on the extracorporeal shockwave lithotripsy (ESWL) results in patients with urolithiasis (UL). Methodology 150 patients with UL (aged 18–65 years) treated with ESWL method were divided into 2 equal groups. The main group (n = 75) received standard recommendations and herbal preparation (12 months). The control group (n = 75) received standard recommendations only. The following was evaluated: time and degree of elimination of fragments; the presence of pain and leukocyturia; recurrent stone formation. Results The elimination of fragments was observed up to 14 days in 94.7% of patients in the main group versus 76% of patients in the control group. Renal colic was observed in 6.7% of patients in the main group versus 10.7% of patients in the control group; cases of leukocyturia were observed within 14 days in 10.7% versus 22.7%, respectively. During the year, a recurrent lithiasis was diagnosed in 6.7% of patients in the main group and in 16% of patients in the control group. Conclusion The use of BNO 1040 extract in combination with ESWL: contributes to more rapid and safe elimination of fragments of the calculi and reduces the risk of recurrent stone formation. Trial registration DRKS ID 00021200. Registered retrospectively in German Clinical Trial Register 27.03.2020. https://www.drks.de/

Effect of phytoneering remedy BNO 2103 on the course of experimental exudative inflammation caused by different phlogogens

“…These pharmacological properties of BNO 2103 are determined by a complex of biologically active substances (fla-vonoids, phenolic acids, essential oils), which are contained in the plant material of the test drug -a mixture of centaury herb, rosemary leaves and lovage root [15]. It is important to note that BNO 2103 is a fixed composition of plant components and a special attention is paid to standardization and reproducibility of technology in the manufacturing process, which is an undeniable advantage of this remedy, taking account of a great variability of plant ingredients.…”

Протизапальні Властивості Стандартизованої Рослинної Композиції BNO 2103 У Щурів З Флогоген-Індукованим Набряком Стопи

“…Для [6,20]. Такий ефект може бути зумовлений наявністю біологічно активних речовин, які містяться в основних компо-нентах засобу -листі розмарину, корені любистку та траві золототисячника [21].…”