Efficacy of azithromycin in prevention of Pneumocystis carinii pneumonia: a randomised trial

Prevalence of colonisation and genotypic characterisation of Pneumocystis jirovecii among cystic fibrosis patients in Spain

“…A further 24 patients were treated with azithromycin, which is used in CF treatment for its anti‐inflammatory and antibacterial properties [23]. Previous studies have shown that azithromycin is also effective for PcP prophylaxis [24,25], but P. jirovecii was detected in five (20.8%) of 24 patients treated with azithromycin in the present study, although none developed PcP during the course of the following year.…”

Discontinuation of Prophylaxis againstMycobacterium aviumComplex Disease in HIV-Infected Patients Who Have a Response to Antiretroviral Therapy

“…Azithromycin prophylaxis also reduces the risk of Pneumocystis carinii pneumonia and bacterial infections. 3,4,8 Since the studies of prophylaxis against M. avium complex disease were performed, more potent antiretroviral regimens have been introduced that suppress HIV replication and increase the CD4+ cell count. 9 Marked decreases in the incidence of major infectious complications, especially P. carinii pneumonia and M. avium complex disease, have been reported in patients treated with these regimens.…”

Erythromycin and Common Cold in COPD

“…On the other hand, macrolide antibiotics have been reported 7 to have effects other than antiinflammatory or antibacterial. For example, azithromycin is effective in preventing P carinii pneumonia in HIV-1-infected patients.…”

“…Likewise, azithromycin is effective in preventing Pneumocystis carinii pneumonia in HIV-1-infected patients. 7 However, to our knowledge, the efficacy of erythromycin therapy for the prevention of the common cold and subsequent exacerbations in COPD patients has not been reported on. We therefore investigated whether erythromycin therapy lowers the frequency of common colds and exacerbations of COPD in a prospective, randomized, controlled trial.…”