Efficacy of bandage contact lens for the management of dry eye disease after cataract surgery

Abstract

Purpose We aimed to evaluate the efficacy of bandage contact lens (BCL) for the management of dry eye disease (DED) after cataract surgery. Methods A total of 120 patients (140 eyes) with age-related cataract and DED were enrolled in this study. Patients underwent standard micro-incision phacoemulsification surgeries and were divided into control or BCL groups. Slit-lamp biomicroscopic examination, Ocular Surface Disease Index, keratograph analysis and Schirmer I test were executed, and the levels of tear inflammatory molecules were detected. Results In the control group, the NIAvg-BUT and Schirmer I test scores were significantly decreased at 1 week post-operation compared with baseline levels (P = 0.035 and P = 0.009, respectively). In the BCL group, the NIF-BUT and Schemer I test scores were significantly improved at 1 month after operation compared with the control group (P = 0.012 and P < 0.001, respectively). Levels of IL-6, IL-8 and ICAM-1 were significantly increased in the control group at 1 month after the operation (P = 0.005, P = 0.038 and P = 0.022, respectively), while there was no difference in the BCL group. The increase in the IL-6 level in the control group was significantly higher compared with that in the BCL group (P = 0.047). In DED patients, there were significant correlations between ocular surface parameters and inflammatory molecules. Conclusions Cataract surgery could lead to the development or worsening of DED. The application of BCLs after cataract surgery could stabilize the ocular surface and tear film, improve the corneal healing and reduce the inflammation. Collectively, our findings suggested that proper use of BCLs after cataract surgery played an effective role in the management of DED. Trial registration ClinicalTrials, NCT04100031. Registered 18 September 2019—retrospectively registered

The efficacy of bandage contact lens in relieving the aggravation of dry eye disease after complicated cataract or/and IOL surgery

“…[23] Additionally, complicated cataract or/and IOL surgery takes a longer time, and tissue trauma is larger, which promotes a more serious in ammatory reaction. [9] Some researchers have implicated that in ammation is closely related to the aggravation of DED. [24] Dan-Na Shi et al [11] have reported the safety of therapeutic BCLs on post-cataract surgery patients.…”

Performance of Bandage Contact Lens in Patients Post-ocular Surgeries: A Systematic Literature Review

“…Similarly, subjective evaluation scores, tear film break-up time, and fluorescein staining improved at week 1 (P¼0.031, P¼0.021, and P¼0.03, respectively) and day 14 (P¼0.009, P¼0.021, and P¼0.032, respectively) in the BCL eye compared with the untreated eye. 14 Lipid tear dysfunction (NIf-BUT; P¼0.008), bulbar redness (P¼0.047), and Schirmer I test score (P¼0.013) showed significant improvement with BCL at 1 month after surgery with reduced inflammation, 57 whereas the tear break-up time (P,0.001) and corneal fluorescein score (P¼0.004) improved rap-idly in eyes with BCL compared with those with eye pads 3 months after surgery. 10 Patient satisfaction scores were higher in the BCL group compared with the eyepatch group (8.3861.59 vs 7.6361.75; P¼0.213), 58 whereas lower corneal fluorescein staining scores (P,0.05) were observed 3 days after surgery with BCL.…”

Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine

“…However, various methods can only reduce but not completely eliminate the symptoms of DED. Artificial tears ( 87 ), silicone eye shields ( 88 ), gas lenses ( 89 ) and corneal contact lenses ( 90 ) are the basic treatment for DED, but in moderate-to-severe DED with ocular surface inflammation, anti-inflammatory and immunosuppressive treatments are essential ( Table 2 ) ( 128 ).…”