Efficacy of combined electrostimulation in patients with acute exacerbation of COPD: Randomised clinical trial

López, Laura; Santiago, Maria Granados; Galindo, Maria Donaire; Torres‐Sánchez, Irene; Ortíz‐Rubio, Araceli; Valenza, Marie Carmen

doi:10.1016/j.medcle.2018.08.011

Cited by 7 publications

(37 citation statements)

References 30 publications

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“…Of the 32 19–50 randomized clinical trials included in this review, nine were on neuromuscular electrical stimulation alone compared to a control or sham, from which six performed neuromuscular electrical stimulation in clinical setting and three performed in home. Twelve studies were on combined neuromuscular electrical stimulation and conventional rehabilitation (pulmonary rehabilitation or physical therapy) compared to conventional rehabilitation, from which eleven performed neuromuscular electrical stimulation in clinical setting and one performed in home.…”

Section: Resultsmentioning

confidence: 99%

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Effects of neuromuscular electrical stimulation on exercise capacity, muscle strength and quality of life in COPD patients: A Systematic Review with Meta-Analysis

et al. 2022

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Objective To determine the effects of neuromuscular electrical stimulation on disabilities and activity limitation of individuals affected by chronic obstructive pulmonary disease. Data sources MEDLINE, PEDro database, Cochrane Controlled Trials Register, and SciELO, were searched from inception until October 2021. Review methods Inclusion criteria were patients with COPD, randomized controlled trials comparing neuromuscular electrical stimulation alone or combined conventional pulmonary rehabilitation and neuromuscular electrical stimulation versus control or sham or pulmonary rehabilitation in disabilities and activity limitation in COPD. There were no mandatory language or publication date restrictions. Two reviewers selected studies independently. Weighted mean differences and 95% confidence intervals were calculated. Results 32 studies met the study criteria, including 1.269 participants. Neuromuscular electrical stimulation improved exercise capacity (MD 1.10, 95% CI: 0.33, 1.86, N = 147), and muscle strength (0.53, 95% CI: 0.20, 0.87, N = 147) compared to sham group. Combined neuromuscular electrical stimulation and conventional rehabilitation improved exercise capacity (MD 34.28 meters, 95% CI: 6.84, 61.73, N = 262) compared to conventional rehabilitation alone. No adverse events were reported. Conclusions Neuromuscular electrical stimulation resulted in small improvement in disabilities and activity limitation (below the MCID) in COPD. Thus, the inclusion of neuromuscular electrical stimulation in rehabilitation programs must consider the cost Because of inadequate methodological conduction and reporting of methods, some studies were of low quality.

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Section: Resultsmentioning

confidence: 99%

“…The final sample was 1.269 participants (ranged from 11 38 to 389 28 ), and mean age of participants ranged 56.3 26 to 76 44 years. Except for two study, 26,49 all others included patients of both genders, but there was a predominance of male. Patient's gender was not informed in three studies.…”

Section: Resultsmentioning

confidence: 99%

Effects of neuromuscular electrical stimulation on exercise capacity, muscle strength and quality of life in COPD patients: A Systematic Review with Meta-Analysis

et al. 2022

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“…Eight studies 43–45 , 49 , 50 , 52–54 (434 participants) provided numerical data for DoHS and were included in this part of the meta-analysis. Significant heterogeneity was not found (χ 2 = 6.95, P = 0.43; I 2 = 0%) and a fixed-effects model was used.…”

Section: Resultsmentioning

confidence: 99%

“…Four studies 43 , 50–52 (193 participants) were included in this part of the meta-analysis. Significant heterogeneity was not observed (χ 2 = 2.46, P = 0.48; I 2 = 0%) so a fixed-effects model was chosen.…”

Section: Resultsmentioning

confidence: 99%

Pulmonary Rehabilitation Programmes Within Three Days of Hospitalization for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis

Zhang¹,

Zhang²,

Li³

et al. 2021

COPD

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Objective To evaluate the efficacy and safety of early pulmonary rehabilitation (PR) (ie, <3 days of hospitalization) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Embase, Web of Science, PubMed and Cochrane Library were searched from their inception to 1 April 2021. Randomized controlled trials were included if they observed the efficacy of early PR in AECOPD patients. Study selection, data extraction, risk of bias and quality of evidence were assessed by two researchers independently. Assessment of the risk of bias and eidence quality were evaluated by the Cochrane Collaboration’s tool and Grading of Recommendations, Assessment, Development and Evaluation system, respectively. Results Fourteen trials (829 participants) were identified. Significant improvement was found in the 6-minute walk distance (6MWD; mean difference (MD): 69.64; 95% CI: 40.26 to 99.01; Z = 4.65, P < 0.0001, low quality). In the subgroup analysis, the exercise-training group showed marked improvement (MD: 96.14; 95% CI: 20.24 to 172.04; Z = 2.48, P = 0.001). The Saint George’s Respiratory Questionnaire (SGRQ) total score was low (MD: −12.77; 95% CI: −16.03 to −9.50; Z = 7.67, P < 0.0001, moderate quality). Significant effects were not found for the duration of hospital stay, quadriceps muscle strength or five times sit to stand test. Only one serious adverse event was reported in experimental group, which was not associated with early PR. Conclusion PR initiated <3 days of hospitalization may increase exercise capacity and improve quality of life, but the results should be interpreted prudently and dialectically, and the role of early PR in AECOPD needs further exploration.

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“…More than half of the studies (52%) were published in the last 5 years, 28,29,35,36,[38][39][40][41][42][43][44][45]50,52 and 37% were published in the previous 15 years. 27,[30][31][32][33]37,[47][48][49]51 Studies were conducted in 11 countries, with the biggest representation from Spain (30%), [39][40][41][42]44,[48][49][50] followed by China (19%), 33,36,38,43,52 and Germany (11%). 26,32,34 Six studies had multiple arms, comparing usual care to more than one intervention that met our criteria.…”

Section: Description Of Studiesmentioning

confidence: 99%

A systematic review of exercise studies for individuals hospitalized with an acute exacerbation of chronic obstructive pulmonary disease: Focus on the principles of exercise training

Moecke,

Zhu,

Gill

et al. 2023

Chron Respir Dis

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Background For exercise interventions to be effectively reproduced or applied in a “real world” clinical setting, clinical trials must thoroughly document all components of the exercise prescription and ensure that participants adhere to each component. However, previous reviews have not critically examined the quality of exercise prescription of inpatient Pulmonary Rehabilitation (PR) programs. Objective The objectives of this review were to evaluate the (a) application of the principles of exercise training, (b) reporting of the frequency, intensity, time and type (FITT) components of exercise prescription, and (c) reporting of patient’s adherence to the FITT components in intervention studies for patients admitted to hospital for an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Relevant scientific databases were searched for randomized controlled trials (RCTs) that compared in-hospital PR with usual care for people hospitalized with AECOPD. Title and abstract followed by full-text screening were conducted independently by two reviewers. Data were extracted and synthesized to evaluate the application of the principles of exercise training and the reporting/adherence of the FITT components. Results Twenty-seven RCTs were included. Only two applied all principles of exercise training. Specificity was applied by 70%, progression by 48%, overload by 37%, initial values by 89% and diminishing returns and reversibility by 37% of trials. Ten trials adequately reported all FITT components. Frequency and type were the components most reported (85% and 81%, respectively), while intensity was less frequently reported (52%). Only three trials reported on the patient's adherence to all four components. Conclusions Studies have not adequately reported the exercise prescription in accordance with the principles of exercise training nor reported all the FITT components of the exercise prescription and patient’s adherence to them. Therefore, interpretation of the current literature is limited and information for developing exercise prescriptions to individuals hospitalized with an AECOPD is lacking.

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Efficacy of combined electrostimulation in patients with acute exacerbation of COPD: Randomised clinical trial

Cited by 7 publications

References 30 publications

Effects of neuromuscular electrical stimulation on exercise capacity, muscle strength and quality of life in COPD patients: A Systematic Review with Meta-Analysis

Effects of neuromuscular electrical stimulation on exercise capacity, muscle strength and quality of life in COPD patients: A Systematic Review with Meta-Analysis

Pulmonary Rehabilitation Programmes Within Three Days of Hospitalization for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis

A systematic review of exercise studies for individuals hospitalized with an acute exacerbation of chronic obstructive pulmonary disease: Focus on the principles of exercise training

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