Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas

Treatment of uterine arteriovenous malformation by myometrial lesion resection combined with artery occlusion under laparoscopy: a case report and literature review

“…8). Previous studies on uterine fibroids or postpartum hemorrhage have demonstrated that the reduction of uterine blood flow after bilateral uterine embolization could bring about ischemia, necrosis or infection in the endometrium, and result in transient or permanent amenorrhea [19][20][21][22]. We therefore speculate that the occlusion of uterine artery was responsible for intrauterine adhesion, since the uterine blood supply was reduced and thereby ischemia and necrosis of the endometrium occurred.…”

“…Some studies [11,17] reported complications of UAE, such as failed embolization, high recurrence rates up to 16.7%, repetitive embolization rate to 21.4%, postembolization syndrome including pelvic pain, nausea, generalized malaise, low-grade fever, mild leukocytosis and a moderate rise of C-reactive protein [18]. In addition, when UAE is used to treat uterine fibroids or postpartum hemorrhage, uterine blood perfusion can be reduced, and this could be one of the reasons for transient or permanent amenorrhea, abortion and infertility [19][20][21][22].…”

The direct and indirect costs of uterine fibroid tumors: a systematic review of the literature between 2000 and 2013

“…[7][8][9][10] In recent years, several new procedures have been approved for the treatment of UF, including high-intensity focused ultrasound, and radiofrequency ablation. [7][8][9] Given the high prevalence of UF, the associated debilitating symptoms affecting daily activities, and the invasiveness of treatment options, the economic burden of UF is considerable. In the U.S., Flynn et al estimated a total direct cost of $3.5 billion (in 2013 USD), including costs for inpatient and outpatient care.…”

“…The medical costs include costs of hospitalization, outpatient visits, drug therapy, and other medical services directly used to treat the disease. The nonmedical costs are rarely studied M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT 8 and reported in literature and could include items such as transportation costs. Indirect costs are those related to resource loss due to a certain disease.…”

Downregulation of the Integrin α_<i>v</i> Signaling Pathway in Uterine Leiomyomas

“…In the literature, Science (2005) described the properties of uterine leiomyomas as multifactorial etiologies [1]. Surgery is the main treatment for symptomatic uterine leiomyomas because prevention or medical treatments still fail to deliver satisfactory results [2,3]. The majority of studies on uterine leiomyomas have focused on surgical techniques and clinical outcomes while conventional biochemical studies have attempted to find the molecules that stimulate myoma growth.…”