Efficacy of Commiphora myrrh mouthwash on early wound healing after tooth extraction: A randomized controlled trial

Eid, Raniah Abdullah Al

doi:10.1016/j.sdentj.2019.11.011

Cited by 18 publications

(15 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mean of final ulcer size decreased with time in both of the studied groups, with the least ulcer size recorded in the myrrh oil Group on the 7 th day of healing intervals in comparison with the control Group. This may be the result of myrrh oil's antibacterial properties, which minimize the time required for wound contraction and eliminate postoperative bleeding [8] and this is in agreement with previous investigations [13][14][15].…”

Section: Discussionsupporting

confidence: 91%

Acceleration of Ulcer Healing by Local Application of Myrrh Oil: An Experimental Study

Abed,

Al- Ghaban

2023

amj

View full text Add to dashboard Cite

Background: Oral mucosa refers to the mucous membrane that lines the tissues within the oral cavity. Wound healing is an essential physiological process that involves the collaboration of numerous cell strains and their products to restore damage caused by a local aggressor. This process begins very early in the inflammatory phase and finishes with tissue repair. Myrrh oil has an anti-inflammatory effect on wound contraction, re-epithelization, early neovascularization, and increased collagen density. Objectives: To evaluate the effectiveness of myrrh oil in rats oral mucosal ulcer healing. Materials and methods: 36 adult male albino rats (Rattus norvegicus) of about 250-300 g of weight and an age of about 2-3 months were used in this experimental study. The practical part of this study lasted two months (June-July 2022) in the private animals' house of Al-Dhyaa in Baghdad City, Iraq. The traumatic ulcer, with an 8 mm diameter and 1 mm depth was made on the right cheek mucosa by using a round diamond bur. The ulcer was treated once daily with a single topical dosage of 10 L of sterile distilled water (control Group). While in the myrrh oil Group, the ulcer was managed once a day with a micropipette dose of 10 ml of 1 mg/ml of myrrh oil. Animals were sacrificed after ulceration with general anesthesia over healing periods 1, 3, and 7 days. Histological analysis was performed by calculating the average wound contraction size, inflammatory cells and epithelial cells, and blood vessels. On days 1, 3, and 7 of the healing process, Van Gieson stain and Periodic Acid-Schiff stain were used to organise collagen fibre deposition and extracellular matrix production in all of the groups that were looked at. Results: Histological findings of an induced oral ulcer treated with daily application of myrrh oil showed more epithelization, reduced inflammation, increased angiogenesis, and decreased healing time in comparison to the control Group. The histochemical findings showed a significant difference in collagen fibers synthesis and extracellular matrix formation in myrrh oil in comparison to the control Group. Conclusion: Myrrh oil is more effective in promoting the healing of ulcers than the control Group.

show abstract

Section: Discussionsupporting

confidence: 91%

Acceleration of Ulcer Healing by Local Application of Myrrh Oil: An Experimental Study

Abed,

Al- Ghaban

2023

amj

View full text Add to dashboard Cite

show abstract

“…In an extraction wound study, Rania Eid found improved wound healing one week postoperatively with a myrrh mouthwash and 90% of participants showed reduced socket opening with a myrrh mouthwash compared to 40% of participants in the control group. A significant decrease in inflammatory signs was found in the myrrh group compared to the control group [ 25 ]. In our study, improvements in wound healing were seen with both the myrrh and CHX mouthwashes.…”

Section: Discussionmentioning

confidence: 99%

Evaluating Soft Tissue Healing after Implant Placement Using Two Different Mouthwashes (Myrrh and Chlorhexidine Gluconate): A Randomized Control Trial

et al. 2022

View full text Add to dashboard Cite

The use of mouthwash is often recommended by dental experts for dental healing. A double-blind, randomized clinical study was conducted to evaluate the efficacy of two mouthwashes (myrrh and chlorhexidine gluconate) on postoperative pain and their effects on tissues after dental implant placement in 35 patients (18 in the myrrh group and 17 in the chlorhexidine gluconate group). Soft tissue healing was evaluated in terms of wound closure, soft tissue swelling, and the color of the gingiva at 1 week postoperative. To decrease the chances for error, only the participants who did not show preoperative symptoms of infection and those who committed to practicing better oral hygiene were included in the study. The samples were evaluated for the infiltration of inflammatory cells (using inflammatory extent and inflammatory cellularity grades), maturation of collagen (osteoblast activity), and arrangement of cells (for detecting the remodeling phase). A questionnaire pertaining to mouthwash satisfaction, the duration of postoperative pain after the procedure, the time of stoppage of bleeding at the surgical site, and any sensitivity at the surgical site was given to the patients. The Chi-square test and Mann–Whitney U-test were used to analyze the data. The difference in postoperative surgical swelling, pain, bleeding, and redness in the patients was not statistically significant between the myrrh and chlorhexidine gluconate mouthwash groups. However, in the acute phase, the myrrh mouthwash showed a positive impact on the process of wound healing after implant placement. The small sample size and inability to compare wound healing in different anatomical areas of the oral cavity were the study limitations.

show abstract

“…The researcher found a significant improvement in gingival bleeding in subjects who used myrrhcontaining toothpaste compared to controls suggesting that myrrhcontaining toothpastes may be helpful as part of the treatment of patients with gingival lesions [7]. In a recent randomized controlled clinical trial, C. Myrrha was tasted in the form of a mouth rinse to evaluate its clinical effects following tooth extractions [8]. 40 subjects were randomized to two equal groups.…”

Section: Saeedi and Coworkers Conducted A Clinical Trial In 2003 Tomentioning

confidence: 99%

Untitled

2021

OJDOH

View full text Add to dashboard Cite

Efficacy of Commiphora myrrh mouthwash on early wound healing after tooth extraction: A randomized controlled trial

Cited by 18 publications

References 28 publications

Acceleration of Ulcer Healing by Local Application of Myrrh Oil: An Experimental Study

Acceleration of Ulcer Healing by Local Application of Myrrh Oil: An Experimental Study

Evaluating Soft Tissue Healing after Implant Placement Using Two Different Mouthwashes (Myrrh and Chlorhexidine Gluconate): A Randomized Control Trial

Untitled

Contact Info

Product

Resources

About