Efficacy of different concentrations of sevoflurane administered through a face mask for magnetic resonance imaging in children

Oğurlu, Mustafa; Orhan, Mehmet Emın; Bilgin, Ferruh; Sızlan, Ali; Yanarateş, Ömer; Yılmaz, Neslihan

doi:10.1111/j.1460-9592.2010.03438.x

Cited by 7 publications

(7 citation statements)

References 22 publications

(24 reference statements)

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“…[119][120][121][122] Observational studies report a high rate of successful imaging in patients receiving deep sedation or light anesthesia, with low rates of motion artifacts (Category B3-B evidence). 103,112,[118][119][120]122,123,[125][126][127][129][130][131][132][133][134][135][136][137][138][139][140][141][142][143][144][145] The Task Force believes that automated apnea monitoring (by detection of exhaled carbon dioxide or other means) may decrease risks during both moderate and deep sedation. 128 Observational studies and case reports also indicate that respiratory depression, oxygen desaturation, bronchospasm, drowsiness, agitation, and vomiting may occur with moderate sedation or light anesthesia (Category B3/4-H evidence).…”

Section: Advisory Statements For Monitoringmentioning

confidence: 99%

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging

2015

Anesthesiology

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Section: Advisory Statements For Monitoringmentioning

confidence: 99%

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging

2015

Anesthesiology

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“…managing uncooperative children for painful procedure, not only for nonpainful radiologic examination. Ogurlu et al [7] reported that sevoflurane could be reliably administered with a face mask at different concentrations. They also noted that with the reduction of sevoflurane concentration (1.5-1.25-1%) inadequate anesthesia did not come about.…”

Section: Discussionmentioning

confidence: 99%

“…Limited number of studies investigated sevoflurane general anesthesia for MRI scan using face mask with spontaneous breathing [7,21].…”

Section: Discussionmentioning

confidence: 99%

“…The use of a face mask that is firmly secured to the face of the child, brings the concentration of sevoflurane needed to maintain general anesthesia at a lower levels, and the spread of sevoflurane throughout the environment is minimal [7]. Ketamine is an effective sedative analgesic and it does not cause respiratory depression at a small dose and does not affect heart rate and blood pressure significantly.…”

Section: Introductionmentioning

confidence: 98%

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Efficacy of ketamine in prevention of agitation in children undergoing magnetic resonance imaging under face mask sevoflurane: A randomized trial

Moawad

El-Diasty

2015

Egyptian Journal of Anaesthesia

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Background: Emergence agitation (EA) is a common distressing problem in children after sevoflurane general anesthesia. The aim of the present study was to test the efficacy of ketamine in prevention of EA after sevoflurane general anesthesia in children undergoing magnetic resonance imaging (MRI) scan. Also, we evaluated the safety and efficacy of the face mask for administration of sevoflurane anesthesia in children. Methods: In this randomized study, 120 children aged 2-7 years (ASA I or II) of either sex scheduled for elective MRI scan under sevoflurane anesthesia were enrolled in the study protocol. Patients were randomly allocated to one of 3 groups: saline group receiving normal saline (n = 40), ketamine 0.25 group receiving 0.25 mg/kg of ketamine intravenously 10 min prior the end of the procedure (n = 40), and ketamine 1.0 group receiving 1.0 mg/kg of ketamine intravenously before sevoflurane induction, (n = 40). Anesthesia was provided with sevoflurane in 100% oxygen. EA score, pausing of the scan, scan time, discharge time and any reported adverse events were recorded. Results: No significant differences as regards age, weight, sex, or ASA score were found among the studied groups. Children in ketamine 1.0 group reported significant lower EA score in comparison with ketamine 0.25 and saline groups (P < 0.05). Ketamine 0.25 group reported significant lower EA score in comparison with saline group (P < 0.05). Children in ketamine 1.0 group reported significant lower incidence of pausing in comparison with ketamine 0.25 and saline groups (P < 0.05). No significant differences as regards nausea, vomiting, desaturation, scan and discharge times among the studied groups (P > 0.05) were found. Conclusion: Ketamine premedication was effective in reducing EA without delay in recovery and significantly reduced the incidence of pausing of MRI scan.

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“…This result was consistent with the report from Ogurlu et al . that sevoflurane mask induction was easily accepted and succeeded in 96% of the children [ 11 ]. In addition, our results showed that the time for anesthesia induction, awakening and leaving the OR in the ketamine group was significantly longer, which may be because the metabolism and clearance of ketamine was relatively slow.…”

Section: Discussionmentioning

confidence: 99%

Clinical research Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients

Yu¹,

Han²,

Zhou³

et al. 2015

aoms

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IntroductionPediatric anesthesia induction with sevoflurane usually needs a special vaporizer and gas source, which limits its use to the operating room (OR). Many children feel anxious and cry when entering the OR because of being separated from their parents, which impairs anesthesia safety and their physical and mental health. In this study, we used a portable circuit to perform sevoflurane anesthesia induction outside the OR, assessed its effects and compared them with those of ketamine anesthesia in pediatric patients.Material and methodsOne hundred children had anesthesia induced with either sevoflurane (sevoflurane group) through the portable inhalational anesthetic circuit, or ketamine by intramuscular injection (ketamine group), then were transferred to the OR. Peak inspired concentration (Cp) and steady state concentration (Cs) of sevoflurane were measured. Heart rate (HR) and saturation of peripheral oxygen (SpO2) were monitored. Time for anesthesia induction, awakening, leaving the OR and duration of the operation were recorded. The patients’ reaction during anesthesia was also analyzed.ResultsThe Cp and Cs of sevoflurane were correlated with bodyweight. Compared with the ketamine group, the sevoflurane group showed shorter time for anesthesia induction (28 ±7 s vs. 195 ±34 s, p < 0.0001), awakening (11.2 ±3.6 s vs. 63.5 ±6.7 s, p < 0.0001) and leaving the OR (20.5 ±5.6 s vs. 43.4 ±10.6, p < 0.0001), less noncooperation during anesthesia induction (10% vs. 80%, p < 0.0001), lower HR (130 ±16 beats/min vs. 143 ±19 beats/min, p = 0.0004) and higher SpO2 (98.9 ±0.9% vs. 96.1 ±2.5%, p < 0.0001) on arrival at the OR.ConclusionsPediatric anesthesia induction by sevoflurane with the portable inhalational anesthetic circuit is convenient, safe and effective outside the OR.

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Efficacy of different concentrations of sevoflurane administered through a face mask for magnetic resonance imaging in children

Abstract: We believe that the administration of sevoflurane at a concentration of 1% via a face mask under spontaneous respiration may provide light anesthesia without complications to induce an unarousable sleep for children during MRI.

Cited by 7 publications

References 22 publications

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging

Practice Advisory on Anesthetic Care for Magnetic Resonance Imaging

Efficacy of ketamine in prevention of agitation in children undergoing magnetic resonance imaging under face mask sevoflurane: A randomized trial

Clinical research Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients

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