Efficacy of Electroconvulsive Therapy in Various Psychiatric Disorders: A Hospital Based Longitudinal Follow-up Study

Kawoos, Yuman; Shah, Irfan; Rather, Yasir Hassan; Wani, Zaid Ahmad; Zarger, Waris Ahmad

doi:10.7860/jcdr/2018/31410.11446

Cited by 2 publications

(4 citation statements)

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“…The number of ECT sessions did not differ significantly between the two groups. Parallel to the results above, in another longitudinal study that compared suicidality before and after ECT using SIS, ECT treatment resulted in significant improvement in suicidality for five patients with unipolar depression and suicidal ideation (p < 0.05) (Kawoos et al, 2018). Suicidality in patients with OCD also decreased significantly (p < 0.05) (Supplementary Table 2).…”

Section: Prospective Studiesmentioning

confidence: 52%

“…Recent ECT studies consistently showed significant clinical effects of ECT on suicidality (Kellner et al, 2005;Bradvik and Berglund, 2006;Patel et al, 2006;Ambade et al, 2009;Keshtkar et al, 2011;Ahmadi et al, 2016;Kawoos et al, 2018;Liang et al, 2018), whereas earlier studies did not show any difference between ECT-treated groups and control patients Winokur, 1976, 1978;Tsuang et al, 1979;Black et al, 1989;Sharma, 1999). This difference may be the result of standardization of ECT techniques, which allowed for retained clinical efficacy and fewer adverse effects (Tirmizi et al, 2012).…”

Section: Ect Studiesmentioning

confidence: 99%

“…There were 11 studies which suicidality was the primary outcome. Seven of these showed an improvement in suicidal ideation or suicide intent and fewer suicide attempts or completed suicides in patients treated with ECT (Avery and Winokur, 1978;Rich et al, 1986;Black et al, 1987;Ciapparelli et al, 2001;Kellner et al, 2005;Bradvik and Berglund, 2006;Patel et al, 2006;Ahmadi et al, 2016;Kawoos et al, 2018). Two of them could not show any significant difference (Avery and Winokur, 1976;Black et al, 1989), while two of them showed a higher rates of completed suicide in the patients treated with ECT (Munk-Olsen et al, 2007;Jorgensen et al, 2020).…”

Section: Ect Studiesmentioning

confidence: 99%

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A Systematic Review of Neuromodulation Treatment Effects on Suicidality

Küçüker

Almorsy

Sonmez

et al. 2021

Front. Hum. Neurosci.

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Introduction: Neuromodulation is an important group of therapeutic modalities for neuropsychiatric disorders. Prior studies have focused on efficacy and adverse events associated with neuromodulation. Less is known regarding the influence of neuromodulation treatments on suicidality. This systematic review sought to examine the effects of various neuromodulation techniques on suicidality.Methods: A systematic review of the literature from 1940 to 2020 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline was conducted. Any reported suicide-related outcome, including suicidal ideation, suicide intent, suicide attempt, completed suicide in reports were considered as a putative measure of treatment effect on suicidality.Results: The review identified 129 relevant studies. An exploratory analysis of a randomized controlled trial comparing the effects of sertraline and transcranial direct-current stimulation (tDCS) for treating depression reported a decrease in suicidal ideation favoring tDCS vs. placebo and tDCS combined with sertraline vs. placebo. Several studies reported an association between repetitive transcranial magnetic stimulation and improvements in suicidal ideation. In 12 of the studies, suicidality was the primary outcome, ten of which showed a significant improvement in suicidal ideation. Electroconvulsive therapy (ECT) and magnetic seizure therapy was also shown to be associated with lower suicidal ideation and completed suicide rates. There were 11 studies which suicidality was the primary outcome and seven of these showed an improvement in suicidal ideation or suicide intent and fewer suicide attempts or completed suicides in patients treated with ECT. There was limited literature focused on the potential protective effect of vagal nerve stimulation with respect to suicidal ideation. Data were mixed regarding the potential effects of deep brain stimulation on suicidality.Conclusions: Future prospective studies of neuromodulation that focus on the primary outcome of suicidality are urgently needed.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=125599, identifier: CRD42019125599.

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Section: Prospective Studiesmentioning

confidence: 52%

Section: Ect Studiesmentioning

confidence: 99%

Section: Ect Studiesmentioning

confidence: 99%

See 1 more Smart Citation

A Systematic Review of Neuromodulation Treatment Effects on Suicidality

Küçüker

Almorsy

Sonmez

et al. 2021

Front. Hum. Neurosci.

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“…The question of whether, and to what extent, ECT is effective in alleviating symptoms of serious mental illness has been demonstrated in reviews of efficacy (e.g. Chan et al, 2019; Kawoos et al, 2018; Palma et al, 2016), and the RCP report that 42.6% of those treated in their accredited clinics who submitted data demonstrated improvement (RCP, 2017). However, in a more recent review, Read et al (2019) explored the quality of 11 ECT studies measuring the efficacy of ECT treatment in relation to depression.…”

Section: Introductionmentioning

confidence: 99%

What are the ethical dilemmas in the decision‐making processes of nursing people given electroconvulsive therapy? A critical realist review of qualitative evidence

Sweetmore

2021

Psychiatric Ment Health Nurs

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Accessible Summary What is known on the subject? ECT is a treatment which has a long and complicated history. There is no consensus on its effectiveness and there is a great deal of polarized debate as to whether it should be used. MHNs are asked to work with people who are receiving ECT as part of their duties. What the paper adds to existing knowledge? The paper seeks to move beyond the polarized arguments and to consider how MHNs can work with people where ECT is being considered or administered as part of their treatment in a manner which satisfies their professional obligations. Implications for practice MHNs may need to broaden their understanding of ethics beyond the traditional biomedical ethics model of beneficence, non‐maleficence, justice and autonomy, as well as improving their understanding of social and political factors which may have an unseen effect of the use of ECT as a treatment in order to meet their professional obligations when working with people being administered ECT. Abstract INTRODUCTIONElectroconvulsive therapy (ECT) has a complex and contentious place in psychiatric care. Mental health nurses (MHNs) are of obligated to be part of this practice despite ethical concerns. AimTo consider the ethical dilemmas and decision‐making processes facing MHNs involved in the administration of ECT. MethodA critical realist review of the literature surrounding ethical considerations and ECT was undertaken using thematic analysis. FindingsFour key themes emerged: the MHN as an advocate and conflict in their role, issues surrounding consent, questionable efficacy and unknown method of action, side effects, and legal issues and clinical guidelines. DiscussionUsing a critical realist framework for understanding, the decision‐making process and ethical considerations are viewed as part of the empirical and actual parts of reality, while the potential for other, unseen causal powers to be at play is acknowledged. Implications for practiceMHNs need to ensure they have an adequate ethical underpinning to their practice to enable them to navigate contentious areas of practice such as ECT to practice effectively and preserve safety. This may require moving beyond the traditional biomedical model of ethics. Developing an appreciation of unseen causal factors is also an essential part of MHNs’ developing professional competency.

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Efficacy of Electroconvulsive Therapy in Various Psychiatric Disorders: A Hospital Based Longitudinal Follow-up Study

Cited by 2 publications

References 0 publications

A Systematic Review of Neuromodulation Treatment Effects on Suicidality

A Systematic Review of Neuromodulation Treatment Effects on Suicidality

What are the ethical dilemmas in the decision‐making processes of nursing people given electroconvulsive therapy? A critical realist review of qualitative evidence

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