Efficacy of Emilia coccinea aqueous extract on inhibition of α-amylase enzyme activity and insulin resistance in dexamethasone treated-rats

Melatonin Takes the Edge off Dexamethasone-Induced Testicular Damage via Modulating Antioxidative Enzymes and Interactive Dialogues between Androgen (AR) and Melatonin Receptors (Mt1/Mt2)

“…In earlier studies, it was found that dexamethasone administration decreased the rat's body weight [29,30]. This weight reduction can be partly attributed to decreased food intake, as demonstrated in earlier studies [31,32], Additionally, the weight loss observed in these animals is the cause of increased muscle loss and the breakdown of proteins and fats [33].…”

Acute and Prolonged Effects of a Polyherbal Formulation on Blood Glucose, Lipid Profile and Liver Function in Normal and Streptozotocin-Induced Diabetic Rats

“…But its prolonged administration, at least for 7 days, are reported lowering the blood glucose of normal and/or diabetic rats/Human [11] [12] [13] [15] [16] [29]- [34]. Furthermore, aqueous extracts of E. coccinea (215 mg/kg) [19] and T. conophorum seed (500 mg/kg) [25] administered acutely 30 minutes prior to oral glucose load (3 mg/kg) in normal rats are reported reducing the post prandial hyperglycaemia. Moreover, the reported inversely dose-dependent efficacy of T. conophorum seed aqueous extract (500 mg/kg > 1000 mg/kg) [25] was also observed in the present results…”

“…Such a traditional therapeutic potion made from mixture of Emilia coccinea (Ec), Scoparia dulcis (Sd) and Tetracarpidium conophorum (Tc), (EcSdTc) is used in Cameroon coastal region to treat mostly malaria, but also cardiovascular pathologies. Indeed, the hypoglycemic and antidiabetic properties of each of these three plant species have been already highlighted [9]- [19]. However, the assessment of therapeutic potential of their mixture (EcSdTc) used in Cameroonian pharmacopoeia has not yet been the subject of a prior study.…”