Efficacy of essential oil mouthwash with and without alcohol: a 3-Day plaque accumulation model

Abstract

BackgroundThe aim of this study was to evaluate the antiplaque effect of a new alcohol free essential oil mouthwash with respect to a control of an essential oil with alcohol mouthwash, using an in vivo plaque regrowth model of 3-days.MethodsThe study was designed as a double-masked, randomized, crossover clinical trial, involving 30 volunteers to compare two different essential oil containing mouthwashes, during a 3-day plaque accumulation model. After receiving a thorough professional prophylaxis at the baseline, over the next 3-days each volunteer refrained from all oral hygiene measures and had two daily rinses with 20 ml of the test mouthwash (alcohol free essential oil) or the control mouthwash (essential oil with alcohol). At the end of the each experimental period, plaque was assessed and the panelists filled out a questionnaire. Each subject underwent a 14 days washout period and there was a second allocation.ResultsThe essential oil mouthwash with ethanol shows a better inhibitory effect of plaque regrowth in 3-days than the mouthwash test with only essential oil in the whole mouth (plaque index = 2.18 against 2.46, respectively, p < 0.05); for the lower jaw (plaque index = 2.28 against 2.57, respectively, p < 0.05); for the upper jaw (plaque index = 2.08 against 2.35, respectively, p < 0.05); for the incisors (plaque index = 1.93 against 2.27, respectively, p < 0.05); and the canines (plaque index = 1.99 against 2.47, respectively, p < 0.05).ConclusionThe essential oil containing mouthwash without alcohol seems to have a less inhibiting effect on the plaque regrowth than the traditional alcoholic solution.Trial RegistrationClinicalTrials.gov NCT01411618

Effectiveness of an alcohol‐free essential oil‐containing mouthwash in institutionalised elders receiving long‐term care: a feasibility study

“…In addition, the AF‐EOMW showed no clear antiseptic effect compared with tap water rinse. Whereas many studies have assessed the antimicrobial effects of alcohol‐containing EOMW, with mostly positive results, a recent study showed that an EOMW could be less effective when it is alcohol‐free, which supports our findings. Another significant confounding factor that could explain the lack of detected differences in salivary pathogen levels within and between the study groups is the hyposalivation found in many participants.…”

Commercial antimicrobials mouthrinses on caries and periodontitis-related biofilm control: a review of literature

“…They rinsed twice a day for 3 days. EO with alcohol showed better plaque inhibitory effect (plaque index of 2.18 in whole mouth) than alcohol-free solution (plaque index of 2.46) [24].…”

The Effect of Noni Fruit Extract (Morinda citrifolia L.) in Gingivitis Patient

“…Chlorhexidine was effectively preventing and controlling gingivitis that could be used as a plaque control agent that showed the best results as an antiseptic effect. 8 Despite it was effectively as strong antiseptic action, chlorhexidine has side effects such as tooth pigmentation, changes in tasting sensation and the formation of supragingival calculus in long-term use. Other mouthwashes such as povidone iodine in long-term used would give side effects such as iodine sensitivity problems, local erythema, pain, mucosal erosion and major risks associated with thyroid function.…”

“…Other mouthwashes such as povidone iodine in long-term used would give side effects such as iodine sensitivity problems, local erythema, pain, mucosal erosion and major risks associated with thyroid function. 8,9,10 Various side effects arising from using of chemicals in the mouthwash was so many and significant, so it should take another alternative as a raw material to make a mouthwash with minimal side effects, economical and efficacious. The available alternative was the ingredients from the herb.…”