Efficacy of Euphorbia Heterophylla Latex Against Pathogenic Bacteria and Fungi

Ml, Pruthvi; Mk, Mahesh; Mary, Rohini Sahaya

doi:10.22159/ajpcr.2020.v13i6.37341

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…melonis (from 70 to 96%). Moreover, they were also shown to inhibit the germination of all strains at concentrations of 2, 10, 100, and 200 μg/ml ( ML et al, 2020 ).…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Euphorbia species latex: A comprehensive review on phytochemistry and biological activities

et al. 2022

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The genus Euphorbia includes about 2,000 species commonly widespread in both temperate and tropical zones that contain poisonous milky juice fluid or latex. Many species have been used in traditional and complementary medicine for the treatment of various health issues such as dropsy, paralysis, deafness, wounds, warts on the skin, and amaurosis. The medicinal applications of these species have been attributed to the presence of various compounds, and most studies on Euphorbia species have focused on their latex. In this review, we summarize the current state of knowledge on chemical composition and biological activities of the latex from various species of the genus Euphorbia. Our aim was to explore the applications of latex extracts in the medical field and to evaluate their ethnopharmacological potential. The databases employed for data collection, are obtained through Web of Science, PubMed, Google Scholar, Science Direct and Scopus, from 1983 to 2022. The bibliographic data indicate that terpenoids are the most common secondary metabolites in the latex. Furthermore, the latex has interesting biological properties and pharmacological functions, including antibacterial, antioxidant, free radical scavenger, cytotoxic, tumor, anti-inflammatory, healing, hemostatic, anti-angiogenic, insecticidal, genotoxic, and mutagenic activities. However, the role of other components in the latex, such as phenolic compounds, alkaloids, saponins, and flavonoids, remains unknown, which limits the application of the latex. Future studies are required to optimize the therapeutic use of latex extracts.

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“…melonis (from 70 to 96%). Moreover, they were also shown to inhibit the germination of all strains at concentrations of 2, 10, 100, and 200 μg/ml ( ML et al, 2020 ).…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Euphorbia species latex: A comprehensive review on phytochemistry and biological activities

et al. 2022

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Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids

Gracz-Bernaciak

Mazur

Nawrot

2021

IJMS

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Latex, a sticky emulsion produced by specialized cells called laticifers, is a crucial part of a plant’s defense system against herbivory and pathogens. It consists of a broad spectrum of active compounds, which are beneficial not only for plants, but for human health as well, enough to mention the use of morphine or codeine from poppy latex. Here, we reviewed latex’s general role in plant physiology and the significance of particular compounds (alkaloids and proteins) to its defense system with the example of Chelidonium majus L. from the poppy family. We further attempt to present latex chemicals used so far in medicine and then focus on functional studies of proteins and other compounds with potential pharmacological activities using modern techniques such as CRISPR/Cas9 gene editing. Despite the centuries-old tradition of using latex-bearing plants in therapies, there are still a lot of promising molecules waiting to be explored.

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Efficacy of Euphorbia Heterophylla Latex Against Pathogenic Bacteria and Fungi

Cited by 2 publications

References 9 publications

Euphorbia species latex: A comprehensive review on phytochemistry and biological activities

Euphorbia species latex: A comprehensive review on phytochemistry and biological activities

Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids

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