Efficacy of extracorporeal shockwave therapy for knee osteoarthritis: a randomized controlled trial

Zhao, Zhe; Ru-fang, Jing; Shi, Zhan; Zhao, Bin; Ai, Quan; Xing, Gengyan

doi:10.1016/j.jss.2013.07.004

Cited by 86 publications

(130 citation statements)

References 25 publications

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“…In the animal model it was verified that the application of SW does not induce pathological changes in the articular cartilage 9,11,13,19,20 . Furthermore, SW improves joint function, reduces inflammatory cytokines which are responsible for osteoarthritic degeneration and enhances the recovery effects 13 .…”

Section: Discussionmentioning

confidence: 85%

Chondrocytes treated with different shock wave devices

Notarnicola

Iannone

Maccagnano

et al. 2017

MLTJ

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SummaryBackground: Shock wave treatment is used for several orthopedic diseases and there are different devices available. Until now, there have been no experimental studies on the effects of these different generators. Methods: We carried out an experimental study to compare the effects of three focused generators (electro-magnetic, piezoelectric and electro-hydraulic) as well as a radial generator on healthy and osteoarthritis chondrocytes. Results: By the analysis of our results, we may exclude significant differences between the different generators, even though there is a greater action specificity for electro-magnetic and piezoelectric generators.

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Section: Discussionmentioning

confidence: 85%

Chondrocytes treated with different shock wave devices

Notarnicola

Iannone

Maccagnano

et al. 2017

MLTJ

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“…[17][18][19] Others report that the ESWT would involve a stimulation of a neovascularization. 17,20,21 Another probable explanation given by Zhao et al 10 is the alteration of the afferent pain mechanisms. Those authors used ESWT on individuals with knee osteoarthritis and also found a reduction in pain intensity as measured by VAS after treatment.…”

Section: Discussionmentioning

confidence: 99%

“…Shockwave therapy has been used to treat pain because it is not invasive, has low rates of complication, does not require hospitalization, and is relatively low cost when compared to other conservative treatments or to surgical procedures. 10 There is a report that the application of ESWT shows a chondroprotective effect in the inhibition of OA in rats 11 and that it even has a multifunctional effect on the bones and cartilage. 11 Although ESWT is also considered effective in reducing pain, few studies have applied this technique on humans.…”

Section: Introductionmentioning

confidence: 99%

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Influence of shockwave therapy on pain in women with knee osteoarthritis

Imamura¹,

Alfieri²,

Plapler³

et al. 2015

Acta Fisiátrica

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Osteoarthritis is the most common articular disease that causes pain to its sufferers. Shockwave therapy is among the many treatments that can be used. Objective: The objective of this study was to observe the influence of shockwave therapy on the intensity of pain in elderly women with knee OA. Method: In this study, 40 elderly females (69.57 ± 6.42 years) were submitted to weekly shockwave therapy with 2000 impulses at 2.5 to 4.0 bar, at a frequency of 8Hz, at the location most painful to touch in the knee, the medial articular interline, for three consecutive weeks. The effect of its application on the pain was evaluated by the visual analogue scale before and after the treatment. Results: There was a significant reduction (p < 0.0001) of pain intensity in the volunteers, going from 7.86 ± 1.07 cm to 5.32 ± 2.26 cm. Conclusion: The application of shockwave therapy has been shown to reduce pain in elderly females with osteoarthritis. Keywords

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“…Zhao et al [25] used ESWT to treat knee OA over 12 weeks and compared it with placebo treatment. Seventy patients were randomized to receive either placebo (n = 36) or ESWT (n = 34).…”

Section: Right Kneementioning

confidence: 99%

Effect of Nonpharmacological Therapies on Pain and Health Perception in Patients with Knee Osteoarthritis

Lizis¹,

Kobza²,

Mańko³

et al. 2017

Pain Relief - From Analgesics to Alternative Therapies

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Objective: Comparing the eiciency of ultrasound therapy (US) versus extracorporeal shock wave therapy (ESWT) on pain and perceived health in men with bilateral knee osteoarthritis (OA). Design: A pilot randomized trial with concealed allocation, assessor blinding and intention-to-treat analysis was conducted.Participants: 60 men, 44-66 years old were randomized to an experimental (US) and a control (ESWT) group. Intervention: The participants in both groups atended 5-week treatments. The experimental group received continuous US and a series of 10 treatments two times per week. The control group received 5 ESWT treatments once per week. Outcome measures:The primary outcome was visual analogue scale (VAS) pain ratings. The secondary outcome measured perceived health using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The examinations were taken before and after the treatment. Results: After 5-week treatment the experimental group had signiicantly worse scores than the control group on the VAS for pain, and on the WOMAC for perceived health. Conclusion: Patients with knee OA can achieve signiicant beter health beneits caused by ESWT than by US.

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Efficacy of extracorporeal shockwave therapy for knee osteoarthritis: a randomized controlled trial

Cited by 86 publications

References 25 publications

Chondrocytes treated with different shock wave devices

Chondrocytes treated with different shock wave devices

Influence of shockwave therapy on pain in women with knee osteoarthritis

Effect of Nonpharmacological Therapies on Pain and Health Perception in Patients with Knee Osteoarthritis

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