Efficacy of Hearing Aids on the Cognitive Status of Patients with Alzheimer’s Disease and Hearing Loss: A Multicenter Controlled Randomized Trial

Nguyen, Marie-France; Bonnefoy, Marc; Adrait, Arnaud; Gueugnon, Marine; Petitot, Charles; Collet, Lionel; Roux, Adeline; Perrot, Xavier

doi:10.3233/jad-160793

Cited by 57 publications

(80 citation statements)

References 69 publications

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“…They did not find a group difference between the immediate treatment and delayed control group after 6 months. 78 However, these findings should be interpreted cautiously as detailed in a response by Mamo and Palmer. 81 Most notably, the HA fitting protocol did not include verification with real-ear measures, which often results in the hearing output providing insufficient amplification for improved speech understanding.…”

Section: Hearing Interventions For Individuals With Dementia: the Evimentioning

confidence: 92%

“…In the few studies that have been conducted that assessed the cognitive abilities of adults with dementia following HA fitting, results have not shown substantial improvements in cognitive function. Nguyen and colleagues 78 and Adrait and colleagues 79 described a multicenter randomized control trial to determine if the use of HAs improves cognition and behavior in 51 individuals with probable Alzheimer's disease and hearing loss. In their companion papers, participants were randomly assigned to either active HA group or a placebo HA group for 6 months.…”

Section: Hearing Interventions For Individuals With Dementia: the Evimentioning

confidence: 99%

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Dementia and Hearing Loss: Interrelationships and Treatment Considerations

2018

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Hearing loss is common among typically aging older adults and those with dementia. In recent years, there has been a renewed interest in the relationship between hearing and cognition among older adults, and in hearing loss as a modifiable risk factor for dementia. However, relatively less attention has been focused on the management of hearing loss among individuals with dementia and the key roles of speech-language pathologists and audiologists in providing such care. In this article, the authors review the literature on hearing loss and dementia, and analyze the research evidence for treatment of hearing loss in the context of major neurocognitive disorders, such as Alzheimer's disease. This article provides an up-to-date review of research evidence for hearing interventions, as well as recommendations for speech-language pathologists and audiologists to work together to ensure access to hearing health care and increased opportunities for meaningful life engagement for people with dementia and hearing loss.

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Section: Hearing Interventions For Individuals With Dementia: the Evimentioning

confidence: 92%

Section: Hearing Interventions For Individuals With Dementia: the Evimentioning

confidence: 99%

Dementia and Hearing Loss: Interrelationships and Treatment Considerations

2018

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“…Furthermore, tinnitus occurs in different percentages in groups of patients with various causes of hearing loss ranging from 30% (in ototoxicity) to 90% (in acoustic trauma). The significant benefit of hearing aids for hearing difficulties have been demonstrated in RCTs [111,128,144].…”

Section: No Recommendation For (Tinnitus); Recommendation For (Deafness)mentioning

confidence: 99%

A multidisciplinary European guideline for tinnitus: diagnostics, assessment, and treatment

Cima

Mazurek

Haider

et al. 2019

HNO

312

334

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“…Since many studies using various approaches have been attempted with small sample sizes, unbiased evaluation in a fully powered trial is needed. The cognitive benefit of hearing aids was evaluated in 51 patients with AD over the age of 65 years in a multicenter double-blind randomized placebo-controlled trial [65]. The primary endpoint was a change from baseline of the Alzheimer's Disease Assessment Scale-Cognitive subscale after a 6-month period.…”

Section: Conceivable Effect Of Hearing Interventionconsideration Basementioning

confidence: 99%

Age-related hearing loss and cognitive decline — The potential mechanisms linking the two

et al. 2019

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The amount of attention to age-related hearing loss (ARHL) has been growing, not only from the perspective of being one of the most common health conditions affecting older adults, but also from the perspective of its relation to cognition. Results from a number of epidemiological and laboratory studies have demonstrated a significant link between ARHL and cognitive decline. The Lancet International Commission on Dementia, Prevention, Intervention, and Care has estimated that mid-life hearing loss, if eliminated, might decrease the risk of dementia by nine percent, since hearing loss is a modifiable age-associated condition linked to dementia. Despite numerous research efforts, elucidation of the underlying causal relationships between auditory and cognitive decline has not yet reached a consensus. In this review article, we focused on the hypotheses of etiological mechanisms between ARHL and cognitive decline: (1) cognitive load hypothesis; (2) common cause hypothesis; (3) cascade hypothesis; and (4) overdiagnosis or harbinger hypothesis. Factual evidence obtained in previous studies was assessed to understand the link between ARHL and cognitive decline or dementia. Additionally, an overview of the conceivable effects of hearing intervention, e.g., hearing aids and cochlear implants, on cognition were presented, and the role of hearing aid use was considered for the relevant hypotheses. We should continue to strive for social enlightenment towards the importance of 'hearing well', and cultivate a necessity for hearing screening among patients at risk of cognitive decline.

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Efficacy of Hearing Aids on the Cognitive Status of Patients with Alzheimer’s Disease and Hearing Loss: A Multicenter Controlled Randomized Trial

Abstract: No significant effect of HA use was observed after 6 months of follow-up in patients with AD and HL.

Cited by 57 publications

References 69 publications

Dementia and Hearing Loss: Interrelationships and Treatment Considerations

Dementia and Hearing Loss: Interrelationships and Treatment Considerations

A multidisciplinary European guideline for tinnitus: diagnostics, assessment, and treatment

Age-related hearing loss and cognitive decline — The potential mechanisms linking the two

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