Efficacy of hypnotherapy compared to cognitive behavioral therapy for mild to moderate depression - Results of a randomized controlled rater-blind clinical trial

Fuhr, K; Meisner, Christoph; Broch, Angela; Cyrny, Barbara; Hinkel, Juliane; Jaberg, Joana; Petrasch, Monika; Schweizer, Cornelie; Stiegler, Anette; Zeep, Christina; Batra, Anil

doi:10.1016/j.jad.2021.02.069

Cited by 39 publications

(59 citation statements)

References 19 publications

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“…The present study is part of a randomized controlled trial (RCT), which focussed on the treatment of Major Depression with psychotherapy. It was found that Hypnotherapy (HT) was non‐inferior to CBT in reducing depressive symptoms in patients with mild‐to‐moderate depressive episodes (Fuhr et al., 2021). The present study is of exploratory nature and was not planned before.…”

Section: Methodsmentioning

confidence: 99%

“…The trial was registered within ClinicalTrials.gov (NCT02375308). The study protocol was already published elsewhere (Fuhr, Schweizer, Meisner, & Batra, 2017).…”

Section: Methodsmentioning

confidence: 99%

“…However, previous RCTs had small sample sizes or methodological quality was low. In a recent RCT, it was found that HT was not inferior to CBT in the treatment of major depression (Fuhr et al., 2021). Even if different forms of psychotherapy are available, there is still a large number of patients without adequate response to the treatment.…”

Section: Introductionmentioning

confidence: 99%

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How does early symptom change predict subsequent course of depressive symptoms during psychotherapy?

2021

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Objectives Previous studies reported about the influence of early changes on treatment response. However, the question of whether early changes can predict the subsequent course of depressive symptoms during treatment with psychotherapy has not yet been clearly answered. We aimed to investigate whether symptom course in the first weeks at the level of individual session can predict the further symptom progression on a session to session level during psychotherapy treatment in patients with Major Depression (MD). Design Monocentric randomized controlled trial with psychotherapeutic treatment either with cognitive‐behavioural therapy (CBT) or hypnotherapy (HT). The longitudinal course of weekly depressive symptoms during the six months treatment period was examined. Methods In this RCT with 152 randomized patients suffering from current mild‐to‐moderate MD, depressive symptoms were assessed on a weekly basis during the 20 sessions’ treatment with individual psychotherapy. We only included patients for which sufficient data for our analysis were available. Three different linear and quadratic mixed model analyses with random effects for each patient were tested: Early change was defined as the individual percentage symptom change during the first two, three, four and five weeks. Symptoms from session four, five, six and seven onward were predicted using different models, with early change added to the model in a final step. Calculating all models separately for CBT and HT lead to comparable results. Result A slow symptom decrease after session four, five, six, seven onward to the end of the treatment was found. However, adding early change to the model, had no effect on the further symptom course in all models. Conclusion Symptom changes at early stages of psychotherapy should not be considered as being predictive for further symptom course. Practitioner points The individual early symptom change in a treatment with psychotherapy in the first two, three, four, or five weeks of treatment does not predict the subsequent symptom course from session four, five, six, or seven onward at a session to session level. Symptom changes at early stages of psychotherapy should not be considered as being predictive for further symptom course. We found a symptom reduction ranging from 3% to 16% in the first two, three, four, or five weeks. Treatment response between the first and last therapy session was found in 54.5%, the number of remitted patients (with PHQ‐9 scores < 5) was 44.7%. A small symptom improvement of between 0.21 and 0.42 points in the PHQ‐9 scores per week in later stages of psychotherapy is likely in all patients (with and without early symptom improvement).

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Section: Methodsmentioning

confidence: 99%

“…The trial was registered within ClinicalTrials.gov (NCT02375308). The study protocol was already published elsewhere (Fuhr, Schweizer, Meisner, & Batra, 2017).…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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How does early symptom change predict subsequent course of depressive symptoms during psychotherapy?

2021

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“…Fuhr et al [32] conducted a monocentric, two-armed, randomized-controlled, rater-blind clinical trial with the aim to investigate whether hypnotherapy Treatment (HT) is not inferior to Cognitive Behavioral Treatment (CBT). A total of 152 patients with major depression were randomized to either CBT or HT.…”

Section: Clinical Hypnosis For Depressionmentioning

confidence: 99%

“…A significant percentage of disabled could face symptoms of anxiety or depression. Clinical hypnosis suspends the circuitry of fear allowing disengagement from the negative self-hypnosis pathways possibly derived from learned weaknesses namely rumination and distorted memories while opening new avenues of self-governance [30][31][32].…”

Section: Virtual/augmented Reality Hypnosismentioning

confidence: 99%

The Role of Clinical Hypnosis & VR in Special Education

Drigas

Mitsea

Skianis

2021

Int. J. Recent Contrib. Eng. Sci. IT

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Clinical hypnosis is becoming increasingly recognized as a valuable clinical intervention for a wide range of psychological and medical problems. The current review paper seeks to determine the role of clinical hypnosis in learning difficulties, emotional or behavioral problems and physical disabilities. In addition, we co-examine the effectiveness of virtual/augmented reality hypnosis. Finally, we discuss the possible uses of clinical hypnosis within the educational settings. The results showed that hypnosis may hold the keys for new types of metacognitive strategies based on non-verbal pathways of effortless self-regulation.

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Complementary and Alternative Therapies

Blakley¹

2023

Functional Illness of the Head and Neck

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Efficacy of hypnotherapy compared to cognitive behavioral therapy for mild to moderate depression - Results of a randomized controlled rater-blind clinical trial

Cited by 39 publications

References 19 publications

How does early symptom change predict subsequent course of depressive symptoms during psychotherapy?

How does early symptom change predict subsequent course of depressive symptoms during psychotherapy?

The Role of Clinical Hypnosis & VR in Special Education

Complementary and Alternative Therapies

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