Efficacy of individualized homeopathic treatment of insomnia: Double-blind, randomized, placebo-controlled clinical trial

A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Evaluating the Evidence Base of Melatonin, Light Exposure, Exercise, and Complementary and Alternative Medicine for Patients with Insomnia Disorder

“…No study could be selected for ayurveda, chelation, energy healing therapy, folk medicine, reiki, vitamin, massage, music therapy, and qi gong. Of the 40 studies selected, 12 focused on melatonin as possible intervention for insomnia disorder [ 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 ], 9 on meditative movement therapies [ 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 ] (particularly, n = 1 on yoga [ 72 ], 6 on mindfulness [ 73 , 74 , 75 , 78 , 79 , 80 ] and 2 on tai chi [76.77]), 7 on exercise [ 81 , 82 , 83 , 84 , 85 , 86 , 87 ], 5 on natural herbal pharmacotherapy [ 88 , 89 , 90 , 91 , 92 ], 2 on light exposure [ 93 , 94 ], 2 on transcranial magnetic stimulation (rTMS) [ 95 , 96 ], 1 on homeopathy [ 97 ], 1 on hypnotherapy [ 98 ], and 1 on dietary supplements [ 99 ]. Two studies which evaluated exercise [ 82 , 83 ], one study evaluating melatonin [ 61 ], and...…”

“…Included studies focused on different age categories, specifically: 5 studies focused on children and adolescents (<18 years) [ 60 , 61 , 62 , 67 , 68 ], 23 studies focused on working-age adults (18–65 years) [ 70 , 71 , 72 , 73 , 75 , 78 , 79 , 81 , 82 , 83 , 84 , 86 , 87 , 89 , 90 , 91 , 92 , 94 , 95 , 96 , 97 , 98 , 99 ], and 2 studies focused on elderly (>65 years) [ 65 , 80 ]. Ten studies used mixed age samples with adult and elderly participants [ 63 , 64 , 66 , 69 , 74 , 76 , 77 , 85 , 87 , 93 ].…”

“…Twenty studies referred to the Diagnostic and Statistical Manual of Mental Disorder (n = 18, DSM IV; DSM IV TR; DSM-5) [ 62 , 63 , 65 , 66 , 68 , 70 , 71 , 72 , 73 , 80 , 81 , 86 , 87 , 90 , 91 , 95 , 96 , 98 ] or the International statistical classification of diseases and related health problems (n = 2, ICD-10) [ 88 , 97 ] for the diagnosis of insomnia, two studies used International Classification of Sleep Disorders (ICSD) [ 92 , 93 ], three used the Research Diagnostic Criteria for Insomnia Disorder [ 78 , 82 , 83 ] and eight studies used more than one of these categorizations together [ 69 , 76 , 77 , 78 , 79 , 82 , 84 , 89 ]. Of the remaining studies, seven used criteria consistent with DSM-5 categorization [ 60 , 62 , 64 , 67 , 85 , 89 , 94 ].…”

“…No study could be selected for ayurveda, chelation, energy healing therapy, folk medicine, reiki, vitamin, massage, music therapy, and qi gong. Of the 40 studies selected, 12 focused on melatonin as possible intervention for insomnia disorder [60][61][62][63][64][65][66][67][68][69][70][71], 9 on meditative movement therapies [72][73][74][75][76][77][78][79][80] (particularly, n = 1 on yoga [72], 6 on mindfulness [73][74][75][78][79][80] and 2 on tai chi [76.77]), 7 on exercise [81][82][83][84][85][86][87], 5 on natural herbal pharmacotherapy [88][89][90][91][92], 2 on light exposure [93,94], 2 on transcranial magnetic stimulation (rTMS) [95,96], 1 on homeopathy [97], 1 on hypnotherapy [98], an...…”

Konsens: 10 Experten – 10 Statements – Homöopathie in der medizinischen Versorgung

“…Verbesserung der Lebensqualität. Placebo-kontrollierte klinische Prüfungen weisen eine signifikante Verbesserung der Lebensqualität bei Mono- wie auch bei Kombinationstherapie mit homöopathischen Arzneimitteln nach 21 , 22 . Additiv zur leitliniengerechten Behandlung eingesetzte homöopathische Arzneimittel können z.…”