Efficacy of intercostal nerve block with 0.25% bupivacaine in percutaneous nephrolithotomy: A prospective randomized clinical trial

Yadav, Om Kumar; Gupta, Sanjay

doi:10.4103/ua.ua_141_18

Cited by 8 publications

(22 citation statements)

References 23 publications

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“…Bupivacaine and ropivacaine were used for the ICNBs. Two studies ( 7 , 18 ) compared ICNB with PT infiltration, three ( 13 , 20 , 21 ) compared with control while one study ( 19 ) was a three-arm trial including ICNB, PT infiltration, and control. All studies administered ICNB after the procedure, except for Ozkan et al ( 20 ).…”

Section: Resultsmentioning

confidence: 99%

“…Clinicians have also reported that peritubal (PT) infiltration of the nephrostomy tract with an anesthetic can reduce post-operative pain ( 6 ). Amongst nerve blocks, paravertebral, and intercostal nerve block (ICNB) are commonly used to provide post-operative pain relief after PCNL ( 7 , 8 ).…”

Section: Introductionmentioning

confidence: 99%

“…There have been some concerns over complications like pneumothorax with ICNB but the overall incidence is low ( 12 ). A number of studies have assessed the efficacy of ICNB for providing pain relief after PCNL ( 7 , 13 ), but to the best of our knowledge, no review has attempted to systematically analyze level- 1 evidence for its use. Therefore, the purpose of this study was to conduct a systematic literature search and collate data to assess the efficacy of ICNB for pain relief after PCNL.…”

Section: Introductionmentioning

confidence: 99%

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Efficacy of Intercostal Nerve Block for Pain Control After Percutaneous Nephrolithotomy: A Systematic Review and Meta-Analysis

Chen

Zhu

2021

Front. Surg.

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Background: We aimed to assess the efficacy of intercostal nerve block (ICNB) for pain relief after percutaneous nephrolithotomy (PCNL).Methods: An electronic search of the databases of PubMed, Science Direct, BioMed Central, CENTRAL, Embase, and Google Scholar was conducted. All types of studies conducted on adult patients undergoing PCNL, comparing ICNB with control or any other anesthetic method, and reporting postoperative pain outcomes were included.Results: Six studies were included. Studies compared ICNB with peritubal (PT) infiltration and with control. Pooled analysis of ICNB vs. PT infiltration indicated no difference between the two groups for pain scores at 6–8 h (MD −0.44; 95% CI −3.41, 2.53; I2 = 99%; p = 0.77), 12 h (MD −0.98; 95% CI −4.90, 2.94; I2 = 99%; p = 0.62) and 24 h (MD 0.16; 95% CI −0.90, 1.21; I2 = 88%; p = 0.77). Time for first analgesic demand was also not significantly different between the two groups. Meta-analysis of ICNB vs. control indicated statistical significant difference in pain scores between the two groups at 8 h (MD −1.55; 95% CI −2.60, −0.50; I2 = 47%; p = 0.04), 12 h (SMD −2.49; 95% CI −4.84, −0.13; I2 = 96%; p = 0.04) and 24 h (SMD −1.22; 95% CI −2.12, −0.32; I2 = 88%; p = 0.008). The total analgesic requirement in morphine equivalents was not significantly different between the two groups.Conclusions: ICNB may be effective in reducing postoperative pain after PCNL. However, its efficacy may not be greater than PT infiltration. Current evidence is from a limited number of studies. Further, high-quality randomized controlled trials are needed to provide robust evidence.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Efficacy of Intercostal Nerve Block for Pain Control After Percutaneous Nephrolithotomy: A Systematic Review and Meta-Analysis

Chen

Zhu

2021

Front. Surg.

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“…The application of regional anaesthesia is known to possess the highest efficacy in managing pain following surgery of this sort [ 2 ]. There are a number of methods available which may potentially reduce postoperative pain associated with nephrostomy tube placement in PCN, namely intercostal nervous blockade, epidural analgesia, peritubal infiltration of local anaesthetic and paravertebral blockade [ 3 – 5 ]. Paravertabral blocks (PVB) are in use to adequately manage pain arising from a variety of operations on the thorax, abdomen or pelvis.…”

Section: Introductionmentioning

confidence: 99%

Analgesic efficacy of ultrasound guided paravertebral block in percutaneous nephrolithotomy patients: a randomized controlled clinical study

Yaman

Tuglu

2020

BMC Anesthesiol

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Background Paravertabral blocks (PVB) are in use to adequately manage pain arising from a variety of operations on the thorax, abdomen or pelvis. PVB is straightforward, efficacious in operations performed. This study was undertaken to evaluate how efficacious ultrasound-guided thoracic paravertebral block is when used in patients undergoing percutaneous nephrolithotomy (PCN). Methods A total of 44 patients, falling in categories I to III of the American Society of Anesthesiologists, and aged between 18 and 65 years, who were scheduled for PCN, were randomly distributed into two groups. The anaesthetic intervention group (PVB) contained 22 individuals, who were injected at level T8-T9 with 20 mL 0.25% bupivacaine as a single administration. In the control group C, also containing 22 individuals, the intervention was not carried out. The groups were compared after PCN in terms of opioid use, pain score, opioid adverse effects profile and the need for supplemental analgesia. Results Visual analogue scale pain scores whilst at rest or moving were lower at the level of statistical significance in the PVB group compared to controls at 2 and 4 h post-surgery. At 6 and 8 h post-surgery, the control group had a lower VAS score when moving, and this result reached statistical significance (p < 0.05). The controls used more opioid relief than the PVB group and had lower scores for satisfaction (p < 0.05). Conclusion Ultrasound-guided PVB using bupivacaine and an in-plane technique provides effective analgesia in PNL. It is associated with high scores on patient satisfaction and minimal complications. Trial registration ClinicalTrials.gov, NCT04406012. Registered retrospectively, on 27 May 2020.

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“…The application of regional anaesthesia is known to possess the highest e cacy in managing pain following surgery of this sort [2]. There are a number of methods available which may potentially reduce postoperative pain associated with nephrostomy tube placement in PCN, namely intercostal nervous blockade, epidural analgesia, peritubal in ltration of local anaesthetic and paravertebral blockade [3,4,5]. Paravertabral blocks (PVB) are in use to adequately manage pain arising from a variety of operations on the thorax, abdomen or pelvis.…”

Section: Introductionmentioning

confidence: 99%

Analgesic Efficacy of Ultrasound-Guided Paravertebral Block in Patients Undergoing Percutaneous Nephrolithotomy: A Randomised, Controlled Clinical Study

Yaman

Tuglu

2020

Preprint

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Background: Paravertabral blocks (PVB) are in use to adequately manage pain arising from a variety of operations on the thorax, abdomen or pelvis. PVB is straightforward, efficacious in operations performed. This study was undertaken to evaluate how efficacious ultrasound-guided thoracic paravertebral block is when used in patients undergoing percutaneous nephrolithotomy (PCN). Methods: A total of forty-four patients, falling in categories I to III of the American Society of Anesthesiologists, and aged between 18 and 65 years, who were scheduled for PCN, were randomly distributed into two groups. The anaesthetic intervention group (PVB) contained 22 individuals, who were injected at level T8-T9 with 20mL 0.25% bupivacaine as a single administration. In the control group C, also containing 22 individuals, the intervention was not carried out. The groups were compared after PCN in terms of opioid use, pain score, opioid adverse effects profile and the need for supplemental analgesia.Results: Visual analogue scale pain scores whilst at rest or moving were lower at the level of statistical significance in the PVB group compared to controls at 2 and 4 hours post-surgery. At 6 and 8 hours post-surgery, the control group had a lower VAS score when moving, and this result reached statistical significance (p<0.05). The controls used more opioid relief than the PVB group and had lower scores for satisfaction (p<0.05).Conclusion: Ultrasound-guided PVB using bupivacaine and an in-plane technique provides effective analgesia in PNL. It is associated with high scores on patient satisfaction and minimal complications.Trial registration: ClinicalTrials.gov, NCT04406012. Registered retrospectively, on 27 May 2020.

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Efficacy of intercostal nerve block with 0.25% bupivacaine in percutaneous nephrolithotomy: A prospective randomized clinical trial

Cited by 8 publications

References 23 publications

Efficacy of Intercostal Nerve Block for Pain Control After Percutaneous Nephrolithotomy: A Systematic Review and Meta-Analysis

Efficacy of Intercostal Nerve Block for Pain Control After Percutaneous Nephrolithotomy: A Systematic Review and Meta-Analysis

Analgesic efficacy of ultrasound guided paravertebral block in percutaneous nephrolithotomy patients: a randomized controlled clinical study

Analgesic Efficacy of Ultrasound-Guided Paravertebral Block in Patients Undergoing Percutaneous Nephrolithotomy: A Randomised, Controlled Clinical Study

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