Efficacy of intraperitoneal versus intravenous lidocaine for postcesarean pain relief

Murad, Ahmed Walid Anwar; Farag, Mohamed A Elhadi Mohamed; Abosrie, Mahmoud; Alazeem, Ehab Saeed Abd; Mostafa, Asmaa

doi:10.1097/01.ebx.0000488795.50824.57

Cited by 3 publications

(5 citation statements)

References 13 publications

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“…In contrast to our findings, Anwar and his colleagues (2) reported that total 24 hours pethidine consumption was significantly decreased in intraperitoneal lidocaine group than control. Also, Shahin and Osman (8) reported that intraperitoneal application of lidocaine was accompanied with lower morphine consumption than placebo.…”

Section: Figure (1)contrasting

confidence: 99%

“…Regarding the incidence of postoperative complications (e.g. postpartum fever & paralytic ileus) or drug side effects, there were no detected statistically significant differences between the studied groups Also, a study by Anwar and his colleagues (12) reported that postoperative vomiting were less frequently encountered in intraperitoneal lidocaine group than in control, but this was not statistically significant (2) .…”

Section: Figure (1)mentioning

confidence: 76%

“…Table (1) showed no statistically significant differences were observed between groups regarding maternal age, gestational age, previous Cesarean sections and operative time. Table (2) showed that means of visual analogue scale scores estimated at 4, 6 and 12 hrs after Cesarean section were diminished significantly among lidocaine compared to placebo (P<0.001). There were no documented statistically significant differences between groups regarding visual analogue scale pain scoring at 1 hr and 24 hrs.…”

Section: Figure (1)mentioning

confidence: 98%

“…It should also provide excellent pain relief with a minimal risk of adverse consequences. Moreover, it should only involve medications that are very slightly released into breast milk and should not interfere with the mother's ability to care for the infant or the establishment of breastfeeding (2) .…”

Section: Introductionmentioning

confidence: 99%

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Intraperitoneal Lidocaine Instillation for Postoperative Pain Relief after Cesarean Delivery

2023

The Egyptian Journal of Hospital Medicine

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Background: Despite advances in multimodal analgesia, many women still experience inadequate pain control after cesarean delivery. The intraperitoneal use of local anesthetics has proven effective in postoperative pain reduction after open or laparoscopic abdominal surgery. Objectives: We intended to evaluate the efficacy of intraperitoneal lidocaine instillation for relieving postoperative pain in women underwent elective cesarean sections. Patients and methods: A randomized, placebo-controlled, triple-blinded trial carried out at

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Section: Figure (1)contrasting

confidence: 99%

Section: Figure (1)mentioning

confidence: 76%

Section: Figure (1)mentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

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Intraperitoneal Lidocaine Instillation for Postoperative Pain Relief after Cesarean Delivery

2023

The Egyptian Journal of Hospital Medicine

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“…There were four different procedures examined in the studies. Two studies looked at laparoscopic cholecystectomy, two studies looked at abdominal hysterectomy, one study looked at caesarean section and one looked at laparoscopic appendicectomy [20][21][22][23][24][25].…”

Section: Resultsmentioning

confidence: 99%

Intravenous Local Anaesthetic Compared with Intraperitoneal Local Anaesthetic in Abdominal Surgery: A Systematic Review

et al. 2018

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Analgesic effects of intraperitoneal lidocaine in adults undergoing surgery: a systematic review and meta-analysis with trial sequential analysis

Ng,

Lim,

Teoh

et al. 2024

Pain Medicine

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Objective The administration of local anaesthesia in intraperitoneal space as part of the multi-modal analgesic regimen has shown to be effective in reducing postoperative pain. Recent studies demonstrated that intraperitoneal lidocaine may provide analgesic effects. Primary objective was to determine the impact of intraperitoneal lidocaine on postoperative pain scores at rest. Design We carried out a systematic review and meta-analysis according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Methods Databases of MEDLINE, EMBASE, and CENTRAL were searched from their inception date until May 2023. Randomized clinical trials (RCT) comparing intraperitoneal lidocaine and placebo in adults undergoing surgery were included. Results Our systematic review included 24 RCTs (n = 1,824). The intraperitoneal lidocaine group was significantly associated with lower postoperative pain scores at rest (MD: -0.87, 95% CI: -1.04 to -0.69) and at movement (MD: -0.50, 95% Cl: -0.93 to -0.08) among adult patients after surgery. Its administration also significantly decreased morphine consumption (MD: -6.42 mg, 95% Cl: -11.56 to -1.27), lowered the incidence of needing analgesia (OR: 0.22, 95% Cl: 0.14 to 0.35). Intraperitoneal lidocaine statistically reduced time to resume regular diet (MD: 0.16 days; 95% Cl: -0.31 to -0.01), and lowered postoperative incidence of nausea and vomiting (OR: 0.54, 95% Cl: 0.39 to 0.75). Conclusions In this review, our findings should be interpreted with caution. Future studies are warranted to determine the optimal dose of administering intraperitoneal lidocaine among adult patients undergoing surgery.

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Efficacy of intraperitoneal versus intravenous lidocaine for postcesarean pain relief

Cited by 3 publications

References 13 publications

Intraperitoneal Lidocaine Instillation for Postoperative Pain Relief after Cesarean Delivery

Intraperitoneal Lidocaine Instillation for Postoperative Pain Relief after Cesarean Delivery

Intravenous Local Anaesthetic Compared with Intraperitoneal Local Anaesthetic in Abdominal Surgery: A Systematic Review

Analgesic effects of intraperitoneal lidocaine in adults undergoing surgery: a systematic review and meta-analysis with trial sequential analysis

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