Efficacy of laparoscopic ovarian drilling for polycystic ovary syndrome resistant to clomiphene citrate

Abstract

Patients with PCOS as diagnosed based on the Japanese diagnostic criteria include those with increased and normal androgen levels. LOD is considered an effective ovulation induction method for both types of patients with PCOS.

RETRACTED: Laparoscopic ovarian drilling in polycystic ovary syndrome: efficacy of adjusted thermal dose based on ovarian volume

“…Laparoscopic ovarian drilling (LOD) is accepted widely as secondline treatment of patients with polycystic ovary syndrome (PCOS) after failure of clomiphene citrate (CC) therapy (1)(2)(3). Currently the optimum amount of electrosurgical energy needed during LOD to achieve maximum reproductive outcome without risks is uncertain (4).…”

Clomiphene citrate plus tamoxifen versus laparoscopic ovarian drilling in women with clomiphene‐resistant polycystic ovary syndrome

“…We reported an 86% ovulation rate in group 2, which is almost similar to the 84.2% reported by Kato et al [23] and the 73.2% reported by Felemban et al [24]. Although LOD is appropriate for patients who have not ovulated using oral medications and are unwilling or unable to use gonadotropins, it is a costly procedure that must be performed by highly trained specialists and carries surgical risks [12].…”

Comparison of clinical outcomes in clomiphene citrate resistant infertile polycystic ovarian syndrome women after treatment with laparoscopic ovarian drilling (LOD) versus gonadotropins

“…19 In a study done by Kato et al on efficacy of LOD for CC resistant PCOS patients and reported cumulative ovulation rate as 23/32 (71.8%) in women who were treated with LOD followed by CC. 20 Malkawi et al reported, 83.5% ovulation rate in LOD plus CC group and successful ovulation rate of 70.6% and 66.7% with human menopausal gonadotropins (hMG) and pure follicle stimulating hormone (FSH) respectively. 21,22 In present study, inGroup A, out of 12 ovulated women in 1st cycle, 1 (8.3%) got pregnant.…”