Efficacy of laser-assisted uvulopalatoplasty

Lauretano, Arthur M.; Khosla, Rohit K.; Richardson, Glen; Matheson, Jean K.; Weiss, J. Woodrow; Graham, C. Edmund; Fried, Menachem

doi:10.1002/(sici)1096-9101(1997)21:2<109::aid-lsm1>3.0.co;2-u

Cited by 45 publications

(24 citation statements)

References 20 publications

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“…331 A modified uvulopalatopharyngoplasty procedure using a CO 2 laser in the outpatient setting, called laserassisted uvuloplasty, appears also to be of limited efficacy in the treatment of apnea. 332 There are currently no widely applicable, effective medical therapies for OSA, except the treatment of predisposing factors such as hypothyroidism and acromegaly; treating the underlying condition can significantly improve the AHI. 333 No therapy for sleep apnea is easily accomplished and acceptable to all patients.…”

Section: Treatment Options In Osamentioning

confidence: 99%

Sleep Apnea and Cardiovascular Disease

et al. 2008

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Section: Treatment Options In Osamentioning

confidence: 99%

Sleep Apnea and Cardiovascular Disease

et al. 2008

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“…Furthermore, these patients appear to have milder OSA at baseline. Lauretano and colleagues5also documented the poor overall efficacy of LAUP in the treatment of OSA, particularly among patients with mild to moderate disease. In their study the mean AHI increased from 11/h to 19/h in patients with mild OSA and from 23/h to 25/h in patients with moderate OSA.…”

Section: Discussionmentioning

confidence: 99%

Unpredictable results of laser assisted uvulopalatoplasty in the treatment of obstructive sleep apnoea

Ryan

Love

2000

Thorax

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Background-Laser assisted uvulopalatoplasty (LAUP) is increasingly oVered for the treatment of obstructive sleep apnoea (OSA), although there is a lack of objective data to support its indications and eYcacy. A study was undertaken to determine the treatment response to LAUP. Methods-Overnight polysomnography was performed before and at least three months after surgery in 44 consecutive patients with symptomatic mild to moderate OSA (apnoea + hypopnoea index (AHI) >10/h). Pharyngeal dimensions were measured by videoendoscopy (n = 11) and disease-specific quality of life, sleepiness and snoring frequency (n = 16) before and after surgery were determined in subgroups of patients. LAUP was performed under local anaesthesia as a one stage resection of the uvula and soft palate by one of two experienced otolaryngologists. Results-Twelve patients (27%) had a good response (AHI <10/h after LAUP); four (9%) had a partial response (AHI <50% of pre-LAUP value); 15 (34%) had a poor response (AHI >50% of pre-LAUP value); and 13 (30%) patients were worse (AHI >100% of pre-LAUP value). The velopharyngeal cross sectional area and anteroposterior diameter increased following LAUP (p<0.05). Quality of life indices improved significantly in all domains and sleepiness decreased. The snoring index did not decrease significantly. No preoperative anthropometric or videoendoscopic measures were predictive of a good response to LAUP. Patients who were worse after LAUP had milder baseline apnoea severity than those in the other response groups. Conclusions-The treatment response to LAUP is variable and unpredictable, and only a few patients achieve a satisfactory response. There appears to be no relationship between subjective and objective measures of treatment eYcacy. (Thorax 2000;55:399-404)

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“…However, efficacy has been somewhat limited (331). A modified uvulopalatopharyngoplasty procedure using a CO 2 laser in the outpatient setting, called laser-assisted uvuloplasty, appears also to be of limited efficacy in the treatment of apnea (332).…”

Section: Treatment Options In Osamentioning

confidence: 99%