Efficacy of licorice extract on the growth performance, carcass characteristics, blood indices and antioxidants capacity in broilers

Toson, Enas; Latif, Maha Abd El; Mohamed, Ahmed H.; Gazwi, Hanaa S. S.; Saleh, Mohamed; Kokoszyński, Dariusz; Elnesr, Shaaban S.; Hozzein, Wael N.; Wadaan, Mohammed A. M.; Elwan, Hamada A. M.

doi:10.1016/j.animal.2022.100696

Cited by 13 publications

(10 citation statements)

References 19 publications

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“…These shows that glycyrrhiza radix and Atractylodes macrocephala enhance the body's ability to transport oxygen and a large number of red blood cells and hemoglobin are combined to transport to various tissues and organs, thereby improving the body's metabolic capacity, but with no significant effect on the body's immune performance. Toson E et al [40] also reported that supplementation with glycyrrhiza extract in broiler diets increased blood WBC, RBC and HGB levels.…”

Section: Discussionmentioning

confidence: 97%

Effects of Crude Extract of Glycyrrhiza Radix and Atractylodes macrocephala on Immune and Antioxidant Capacity of SPF White Leghorn Chickens in an Oxidative Stress Model

Zhang,

Wang,

Han

et al. 2024

Antioxidants

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The natural edible characteristics of Chinese herbs have led more and more people to study them as an alternative product to antibiotics. In this study, crude extracts of Glycyrrhiza radix and Atractylodes macrocephala (abbreviated as GRAM) with glycyrrhizic acid content not less than 0.2 mg/g were selected to evaluate the effects of GRAM on the immune and antioxidant capacity of model animals. Thirty 21-day-old male Leghorn chickens were weighed and randomly assigned to one of three groups of ten animals each. The treatments comprised a control group (CON), in which saline was injected at day 31, day 33, and day 35, an LPS-treated group (LPS), in which LPS (0.5 mg/kg of BW) was injected at day 31, day 33, and day 35, and finally a GRAM and LPS-treated group, (G-L) in which a GRAM-treated diet (at GRAM 2 g/kg) was fed from day 21 to day 35 with LPS injection (0.5 mg/kg of BW) at day 31, day 33, and day 35. The results of diarrhea grade and serum antioxidant measurement showed that the LPS group had obvious diarrhea symptoms, serum ROS and MDA were significantly increased, and T-AOC was significantly decreased. The oxidative stress model of LPS was successfully established. The results of immune and antioxidant indexes showed that feeding GRAM significantly decreased levels of the pro-inflammatory factors TNF-α, IL-1β, and IL-6 (p < 0.05) and significantly increased levels of the anti-inflammatory factors IL-4 and IL-10 and levels of the antioxidant enzymes GSH-Px and CAT (p < 0.05). GRAM resisted the influence of LPS on ileum morphology, liver, and immune organs and maintained normal index values for ileum morphology, liver, and immune organs. In summary, this study confirmed the antidiarrheal effect of GRAM, which improved the immune and antioxidant capacity of model animals by regulating inflammatory cytokine levels and antioxidant enzyme activity in poultry.

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Section: Discussionmentioning

confidence: 97%

Effects of Crude Extract of Glycyrrhiza Radix and Atractylodes macrocephala on Immune and Antioxidant Capacity of SPF White Leghorn Chickens in an Oxidative Stress Model

Zhang,

Wang,

Han

et al. 2024

Antioxidants

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“…Similarly, the depth of the crypts increased with age on supplementation with 0.01% P. aduncum and the M. citrifolia in 21 and 28 days of age, respectively, compared with those of the positive control ( p < 0.05). Previous studies using extracts from other plants have proven that the length of the intestinal villi increases because of plant extracts or essential oils ( 15 , 16 , 88–90 ), facilitating the mechanisms of nutrient absorption. This is similar to the active mechanisms of antibiotics as growth promoters, which also promote an increase in the length of the intestinal villi ( 5 ).…”

Section: Discussionmentioning

confidence: 99%

“…The results of the present study were similar to those obtained in previous studies, wherein the productive indices of cattle, tilapia, and guinea pigs improved on using pulp and fruit extracts from M. citrifolia ( 100–102 ). Studies have been performed in chickens, where extracts from different plants, such as Indian frankincense, caraway ( Carum carvi L.), cloves ( Syzygium aromaticum ), holy basil ( Ocimum sanctum ), and licorice have shown improved productive indices ( 15 , 16 , 88–90 ). Nonetheless, the results from the present study also contrast with those of previous studies, in which the productive performance indices of chickens did not vary on using of M. citrifolia leaf powder or different fruit extract concentrations ( 33 , 63 ).…”

Section: Discussionmentioning

confidence: 99%

Modulation of Gut Microbiota, and Morphometry, Blood Profiles and performance of Broiler Chickens Supplemented with Piper aduncum, Morinda citrifolia, and Artocarpus altilis leaves Ethanolic Extracts

Paredes-López,

Robles-Huaynate,

Soto-Vásquez

et al. 2024

Front. Vet. Sci.

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Bioactive plants such as P. aduncum, M. citrifolia, and A. altilis might improve intestinal health as an alternative to antibiotic growth promoters. The objective of this study was to determine the effect of the ethanolic extracts (EEs) of these plants on the intestinal health of broiler chickens. Cobb 500 chickens (n = 352) were distributed into eight treatments with four replicates and 11 chickens each. T1 received a base diet, and T2 received a base diet with 0.005% zinc bacitracin. T3, T5, and T7 were supplemented with 0.005% of P. aduncum, M. citrifolia, and A. altilis EE in the diet while T4, T6, and T8 with 0.01% of the extract. The EEs were supplemented with drinking water from 1 to 26 days of age. The following parameters were evaluated: hematological profiles at 28 days of age, blood metabolites profiles at 14, 21, and 28 days; Escherichia coli, Staphylococcus aureus, and Lactobacillus sp. abundance in the ileum mucosa and content at 21 and 28 days, and histomorphometry of the duodenum, jejunum, and ileum mucosa at 14, 21, and 28 d. Final weight (FW), weight gain (WG), feed intake (FI), and feed conversion rate (FCR) were evaluated at seven, 21, and 33 days of age. M. citrifolia and A. altilis EE at 0.01% increased blood glucose levels at 21 and 28 days of age, respectively, and P. aduncum and M. citrifolia EE at 0.01% increased triglycerides at 28 days of age; in addition, this EE did not have any effect on the AST and ALT profiles. The depths of the Lieberkühn crypts and the villi length to the crypt’s depth ratio increased with age on supplementation with 0.01% M. citrifolia and A. altilis EE at 21 days of age (p < 0.05). In addition, the depth of the crypts increased at 28 days of age (p < 0.05) in chickens supplemented with 0.01% A. altilis EE. The 0.01% M. citrifolia EE in diet decreased in the Staphylococcus aureus population in the ileal microbiota (p < 0.05). The FW and WG during the fattening and in the three stages overall increased, and the FCR decreased; however, the FI and the carcass yield did not change in the broiler chickens supplemented with 0.01% M. citrifolia EE (p < 0.05). Conclusively, the M. citrifolia EE at 0.01% of the diet improved intestinal health and thus the performance indices of the broiler chickens and did not have a detrimental effect on any of the parameters evaluated, so it is postulated as a potential alternative to AGP in poultry.

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“…The active components of licorice extract, including triterpenoids and flavonoids, have been shown to improve the anti-inflammatory, antioxidant, and immunomodulatory capacities of the animal organism [23]. The addition of 1 g/kg to 3 g/kg licorice extract to diets can significantly improve the growth performance and antioxidant indexes of chicks [24]. The application of licorice in pig feed can effectively improve the immune function of pigs and can replace the use of antibiotics to a certain extent [25].…”

Section: Discussionmentioning

confidence: 99%

Effects of Spinach Extract and Licorice Extract on Growth Performance, Antioxidant Capacity, and Gut Microbiota in Weaned Piglets

Zhu,

Lian,

Deng

et al. 2024

Animals

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Anemia and weaning stress are important factors affecting piglet growth performance. Spinach extract and licorice extract have been used to improve anemia and antioxidant capacity, respectively. However, whether they have synergistic effects has not been reported. To evaluate the effects of mixed spinach extract and licorice extract on growth performance, serum biochemistry, antioxidant capacity, and gut microbiota in weaned piglets, a total of 160 weaned piglets were randomly allotted to four treatments with four replications of 10 piglets each. The four treatments were as follows: control (CON) group (basal diet), spinach extract (SE) group (basal diet + 1.5 kg/t spinach extract), licorice extract (LE) group (basal diet + 400 g/t licorice extract), and spinach extract and licorice extract (MIX) group (basal diet + 1.5 kg/t spinach extract + 400 g/t licorice extract). The results showed that, compared with the CON group, diets supplemented with spinach extract and licorice extract significantly increased the average daily gain (p < 0.05), while considerably reducing the feed-to-gain ratio (p < 0.05). Moreover, the MIX group exhibited a significant up-regulation of serum total protein, globulin, albumin, glucose, and triglyceride levels in comparison to the CON group (p < 0.05). Meanwhile, both the anemia and antioxidant capacity of piglets were effectively improved. Notably, the MIX group achieved even better results than the individual supplementation in terms of enhancing growth performance, which could potentially be attributed to the increased abundance of the Rikenellaceae_RC9_gut_group. These results demonstrated that the supplementation of diets with spinach extract and licorice extract improves the absorption of nutrients from the diet and antioxidant capacity in weaned piglets.

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Efficacy of licorice extract on the growth performance, carcass characteristics, blood indices and antioxidants capacity in broilers

Cited by 13 publications

References 19 publications

Effects of Crude Extract of Glycyrrhiza Radix and Atractylodes macrocephala on Immune and Antioxidant Capacity of SPF White Leghorn Chickens in an Oxidative Stress Model

Effects of Crude Extract of Glycyrrhiza Radix and Atractylodes macrocephala on Immune and Antioxidant Capacity of SPF White Leghorn Chickens in an Oxidative Stress Model

Modulation of Gut Microbiota, and Morphometry, Blood Profiles and performance of Broiler Chickens Supplemented with Piper aduncum, Morinda citrifolia, and Artocarpus altilis leaves Ethanolic Extracts

Effects of Spinach Extract and Licorice Extract on Growth Performance, Antioxidant Capacity, and Gut Microbiota in Weaned Piglets

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