Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a systematic review and network meta‐analysis of randomized clinical trials

Nagendrababu, Venkateshbabu; Pulikkotil, Shaju Jacob; Suresh, A.; Veettil, Sajesh K.; Bhatia, Shekhar; Setzer, Frank C.

doi:10.1111/iej.13072

Cited by 45 publications

(65 citation statements)

References 40 publications

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“…Example 1d : ‘Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: A systematic review and network meta‐analysis of randomized clinical trials’ (Nagendrababu et al . 2019b).…”

Section: Explanation and Endodontic Examples Of Items In The Prisma Fmentioning

confidence: 99%

“…Example 1c: 'Single-visit or multiple-visit root canal treatment: systematic review, meta-analysis and trial sequential analysis' (Schwendicke & G€ ostemeyer 2017). Example 1d: 'Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: A systematic review and network meta-analysis of randomized clinical trials' (Nagendrababu et al 2019b). Example 1e: 'Ultrasonically activated irrigation to remove calcium hydroxide from apical third of human root canal system: A systematic review of in vitro studies' (Yaylali et al 2015).…”

Section: Examplesmentioning

confidence: 99%

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Preferred reporting items for systematic reviews and meta‐analyses for abstracts: best practice for reporting abstracts of systematic reviews in Endodontology

et al. 2019

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An abstract is a brief overview of a scientific, clinical or review manuscript as well as a stand‐alone summary of a conference abstract. Scientists, clinician–scientists and clinicians rely on the summary information provided in the abstracts of systematic reviews to assist in subsequent clinical decision‐making. The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) for Abstracts checklist was developed to improve the quality, accuracy and completeness of abstracts associated with systematic reviews and meta‐analyses. The PRISMA for Abstracts checklist provides a framework for authors to follow, which helps them provide in the abstract the key information from the systematic review that is required by stakeholders. The PRISMA for Abstracts checklist contains 12 items (title, objectives, eligibility criteria, information sources, risk of bias, included studies, synthesis of results, description of the effect, strength and limitations, interpretation, funding and systematic review registration) under six sections (title, background, methods, results, discussion, other). The current article highlights the relevance and importance of the items in the PRISMA for Abstracts checklist to the specialty of Endodontology, while offering explanations and specific examples to assist authors when writing abstracts for systematic reviews when reported in manuscripts or submitted to conferences. Strict adherence to the PRISMA for Abstracts checklist by authors, reviewers and journal editors will result in the consistent publication of high‐quality abstracts within Endodontology.

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Section: Explanation and Endodontic Examples Of Items In The Prisma Fmentioning

confidence: 99%

Section: Examplesmentioning

confidence: 99%

Preferred reporting items for systematic reviews and meta‐analyses for abstracts: best practice for reporting abstracts of systematic reviews in Endodontology

et al. 2019

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“…It is recommended to raise awareness among clinicians and patients to increase adherence to the post-EM control and maintenance process. evidence 65,66 exclusively focuses on either inferior dental nerve block in symptomatic pulp pain or extraction of third molars. This shows the lack of evidence for anesthetic options in EM.…”

Section: Good Practice Pointmentioning

confidence: 99%

Guía De Práctica Clínica Para El Manejo Quirúrgico en Endodoncia De La Enfermedad Periapical Postratamiento

Guerrero

Rodriguez

Serrano

2019

Rev Fac Odontol Univ Antioq

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Introduction: in Colombia, persisting post-endodontic disease has been reported by up to 45%, validating the use of secondary alternative therapies, like endodontic microsurgery (EM). The aim of this study was to systematically—and with reliable scientific evidence—develop de Novo Clinical Practice Guidelines for the surgical endodontic management of post-treatment periapical disease (PPD), with more accurate recommendations for therapeutic decisions and preferences consulted with both practitioners and patients. Method: the guidelines developers team identified EM as a topic in the literature and established the scope, objective, questions, and outcomes, which were analyzed using the scientific evidence reported in secondary or primary clinical studies. A first screening identified titles and abstracts for each question asked. The validity of the selected studies was quantified with tools like AMSTAR or SIGN. Finally, the strength of recommendations and the quality of evidence were confirmed with GRADE. Results: concepts like PPD, EM indication, use of local anesthetics, antibiotics and presurgical anti-inflammatory drugs, effect of magnification, implementation of cone beam computed tomography, hemostasis, retrograde filling, and control time were integrated, supporting each topic with relevant evidence, experts’ recommendations, and even good practice points. Conclusions: this document is considered a tool with sufficient evidence for clinical decision-making in EM.

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“…Lidocaine, an amine derivative of cocaine, is commonly used as a local anaesthetic and as a class 1b antiarrhythmic drug in both paediatric and adult patients . However, it is also used as an anticonvulsant in neonates refractory to 1 or more other antiepileptic drugs (AEDs) such as phenobarbital and midazolam .…”

Section: Introductionmentioning

confidence: 99%

Lidocaine as treatment for neonatal seizures: Evaluation of previously developed population pharmacokinetic models and dosing regimen

Favié

Huitema

Broek

et al. 2020

Brit J Clinical Pharma

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Aims:Lidocaine is used to treat neonatal seizures refractory to other anticonvulsants. It is effective, but also associated with cardiac toxicity. Previous studies have reported on the pharmacokinetics of lidocaine in preterm and term neonates and proposed a dosing regimen for effective and safe lidocaine use. The objective of this study was to evaluate the previously developed pharmacokinetic models and dosing regimen. As a secondary objective, lidocaine effectiveness and safety were assessed. Methods: Data from preterm neonates and (near-)term neonates with and without therapeutic hypothermia receiving lidocaine were included. Pharmacokinetic analyses were performed using non-linear mixed effects modelling. Simulations were performed to evaluate the proposed dosing regimen. Lidocaine was considered effective if no additional anticonvulsant was required and safe if no cardiac adverse events occurred.Results: Data were available for 159 neonates; 50 (31.4%) preterm and 109 term neonates, of whom 49 (30.8%) were treated with therapeutic hypothermia. Lidocaine clearance increased with postmenstrual age by 0.69%/day (95% confidence interval 0.54-0.84%). During therapeutic hypothermia (33.5 C), lidocaine clearance was reduced by 21.8% (7.26%/ C, 95% confidence interval 1.63-11.2%) compared to normothermia (36.5 C). Simulations demonstrated that the proposed dosing regimen leads to adequate average lidocaine plasma concentrations. Effectiveness and safety were assessed in 92 neonates. Overall effectiveness was 53.3% (49/92) and 56.5% (13/23) for neonates receiving the proposed dosing regimen. No cardiac toxicity was observed.A complete list of non-author contributors appears in the Acknowledgements section.The authors confirm that the Principal Investigators for this paper are Timo R. de Haan and Floris Groenendaal and that they had direct clinical responsibility for patients. Conclusion: Lidocaine pharmacokinetics was adequately described across the entire neonatal age range. With the proposed dosing regimen, lidocaine can provide effective and safe treatment for neonatal seizures. K E Y W O R D Sclinical pharmacology, drug utilization, mass spectrometry, modelling and simulation, neonatology, pharmacometrics

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Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a systematic review and network meta‐analysis of randomized clinical trials

Cited by 45 publications

References 40 publications

Preferred reporting items for systematic reviews and meta‐analyses for abstracts: best practice for reporting abstracts of systematic reviews in Endodontology

Preferred reporting items for systematic reviews and meta‐analyses for abstracts: best practice for reporting abstracts of systematic reviews in Endodontology

Guía De Práctica Clínica Para El Manejo Quirúrgico en Endodoncia De La Enfermedad Periapical Postratamiento

Lidocaine as treatment for neonatal seizures: Evaluation of previously developed population pharmacokinetic models and dosing regimen

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