Efficacy of Lumiracoxib Versus Diclofenac Sodium in Pain Control Following Extraction of Impacted Lower Third Molar

Abstract

ABSTRACT:The aim of this paper was to compare the efficacy of two different anti-inflammatory agents, Diclofenac (Deltaflogin ® ) and Lumiracoxib (Prexige ® ) in the control of postoperative pain that results from surgical removal of impacted lower third molars. Twenty adult patients from the Oral and Maxillofacial Surgery Division of the Araraquara Dentistry School, UNESP who presented bilateral impacted lower third molars were included in the study. Removal of the impacted teeth was performed in each side in different operative moments in a split mouth design for the study. The anti-inflammatory drugs evaluated were randomly administered on the first and second surgical procedures. The pain level was recorded using an analogical visual scale at 6, 24, 48 and 72 hours after surgical intervention. Both lumiracoxib 400 mg and diclofenac 100 mg are efficient for acute pain control after surgical removal of impacted lower third molars. However, lumiracoxib offered better pain control.

Pain measurement in oral and maxillofacial surgery

“…In 2017, Raiesian et al [ 37 ] assessed the effect of low-level laser therapy (LLLT) on pain in LTMI, by complete a questionnaire with the VAS for pain intensity measurement. Further, Nicoli et al [ 38 ] studied the efficacy of two different anti-inflammatory agents, i.e., Diclofenac (Deltaflogin) and Lumiracoxib (Prexige), in postoperative pain control resulting from LTMI, and also assessed pain using the VAS, as did Huskisson in 1983 [ 39 ]. The pain measurement scale also consists of a 100-mm straight line, which allows quantification of the post-operative pain.…”

Efecto analgésico de la asociación de diclofenaco y vitaminas B1, B6 y B12 en cirugía de tercera molar.

“…La cirugía de tercer molar incluido es un procedimiento común en cirugía oral. Posterior a su realización, los pacientes experimentan un cuadro clínico caracterizado por dolor, edema y trismus, el cual los limita en la realización de sus actividades rutinarias [1][2][3] .…”

Control inadecuado del dolor agudo postoperatorio: prevalencia, prevención y consecuencias. Revisión de la situación en Latinoamérica

“…Otro estudio demostró que el bloqueo bilateral del plexo cervical superficial mejoraba la analgesia en cirugía de tiroides, lo que permite disminuir el consumo de opioides y mejorar el postoperatorio de esta cirugía (73) . La cirugía maxilar y bucal ha sido un campo prolífico para la realización de estudios, profundizando en aspectos como el uso de los antiinflamatorios no esteroideos (AINE) (74,75) o de antibióticos como la amoxicilina (76) . Otras cirugías como las de urgencia en el campo de la obstetricia (77) o la cirugía abdominal (78) , o las necesidades especiales en la población geriátrica (79,80) también han sido objeto de investigación.…”