Efficacy of Melochia corchorifolia L. (Sterculiaceae) on Feeding Behavior of Four Lepidopteran Pests

Pavunraj, Manickam; Baskar, K.; Ignacimuth, S.

doi:10.3923/ijar.2012.58.68

Cited by 23 publications

(8 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among various bioactive constituents identified in the T. neriifolia extract, β-sitosterol was reported to possess insect growth regulatory activity [4]. Likewise, the leaf extract of Melochia corchorifolia, which was found to be an effective antifeedant against H. armigera, Spodoptera litura, Earias vittella and Leucinodes orbonalis, contained sterols as one of the bioactive constituents [34].…”

Section: Discussionmentioning

confidence: 99%

Effects of β-sitosterol on growth, development and midgut enzymes of Helicoverpa armigera Hübner

Mishra

Sharma

Dagar

et al. 2020

Arch biol sci (Beogr)

View full text Add to dashboard Cite

Helicoverpa armigera is a global agricultural pest of serious concern. Continued use of chemical insecticides as control measures has raised grave health and environment concerns, necessitating a search for botanicals as safe alternatives. The current study investigates the effects of ?-sitosterol, a bioactive phytocomponent in Thevetia neriifolia, on the growth and development, as well as on midgut enzymes of H. armigera. Dietary ?-sitosterol produced dose-dependent systemic toxicity and growth inhibitory effects in H. armigera; the most significant effects were obtained with 10 ?g/mL dietary ?-sitosterol. Higher prepupal and pupal mortality in comparison to larval mortality and a comparatively greater reduction in average weight gained by later instars point to cumulative effects of ?-sitosterol. The delayed effects were ascertained by the 82.05%-57.89% reduction in adult emergence in comparison to 95.02% emergence in controls. Dose-dependent effects of ?-sitosterol were observed as significantly decreased enzyme activities of alanine aminotransaminase (ALT), aspartate aminotransaminase (AST) and alkaline phosphatase (ALP) in the larval midgut. Suppression of enzyme activity was obtained in the order ALT>AST>ALP. Impaired activity of gut enzymes possibly lowered the energy reserves and affected nutrient transport through the gut epithelium, affecting the growth and development of H. armigera. Our study points to a promising use of ?-sitosterol against H. armigera, although further examination and field studies are needed to ascertain its possible use in control programs.

show abstract

Section: Discussionmentioning

confidence: 99%

Effects of β-sitosterol on growth, development and midgut enzymes of Helicoverpa armigera Hübner

Mishra

Sharma

Dagar

et al. 2020

Arch biol sci (Beogr)

View full text Add to dashboard Cite

show abstract

“…(Fab.) and Leucinodes orbonalis revealed presence of steroids in the most effective fraction of the leaf extract of Melochia corchorifolia (Pavunraj, Baskar, & Ignacimuthu, 2012).…”

Section: Discussionmentioning

confidence: 96%

Docking-Based Virtual Screening Ascertaining β-Sitosterol-Induced Alterations in the Helicoverpa armigera Hübner Gut Enzymes

Mishra

Sharma²,

Dagar³

et al. 2022

jers

View full text Add to dashboard Cite

Present investigation attempts to study binding of β-sitosterol with Helicoverpa armigera midgut enzymes; alanine aminotransaminase (ALT), aspartate aminotransaminase (AST) and alkaline phosphatase (ALP); through docking-based virtual screening. Extraction of the protein sequence of the enzymes revealed a respective linear chain of 535, 522 and 430 amino acids for ALP, ALT and AST. The binding energy for ALT-ligand complex was lowest as compared to the AST and ALP-docked complexes. The ALT-docked complex had ligand efficiency of (-) 0.32 with an inhibition constant of 104.01, more hydrogen bonds and hydrophobic interactions leading to a more stable complex. However, unfavored bumps in AST and ALP complexes may have led to comparatively unstable complexes. The dietary β-sitosterol exhibits differential binding with midgut enzymes of H. armigera larvae. The strong binding of β-sitosterol with ALT indicates the highest inhibition of ALT activity due to the activity-stability trade-off. The enzymes, AST and ALP exhibited relatively higher activity as a resultant of lesser stabilization of the β-sitosterol-enzyme complex. In silico studies have indicated that β-sitosterol can be used an effective control agent against H. armigera.

show abstract

“…Laboratory studies have shown that M. corchorifolia extracts exhibit hepatoprotective, antioxidant, and anti-pest effects in vitro (Pavunraj et al. 2012 ; Rao et al. 2013 ).…”

Section: Introductionmentioning

confidence: 99%

The complete chloroplast genome sequence of Melochia corchorifolia Linnaeus, 1753 (Sterculiaceae)

Wang,

Wang

2024

Mitochondrial DNA Part B

View full text Add to dashboard Cite

Melochia corchorifolia Linnaeus, 1753, is a weedy tropical plant of the Sterculiaceae family and has medicinal value. We sequenced the complete chloroplast genome of M. corchorifolia using Illumina high-throughput sequencing and examined phylogenetic relationships with closely related species. The assembled chloroplast genome of M. corchorifolia was 163,693 bp long and contained a pair of inverted repeats of 29,729 bp, separated by a large single-copy sequence of 84,350 bp and a small single-copy region of 19,885 bp. A total of 136 genes were annotated across the entire chloroplast genome, including 37 transfer RNA, 8 ribosomal RNA, and 91 protein-coding genes. The GC content of the complete cp genome was 37.27%. The phylogenetic tree indicated that M. corchorifolia is closely related to Melochia pyramidata (Malvaceae). These results would provide useful information for future phylogenetic, taxonomic, and evolutionary studies on Sterculiaceae and Malvaceae.

show abstract

Efficacy of Melochia corchorifolia L. (Sterculiaceae) on Feeding Behavior of Four Lepidopteran Pests

Cited by 23 publications

References 0 publications

Effects of β-sitosterol on growth, development and midgut enzymes of Helicoverpa armigera Hübner

Effects of β-sitosterol on growth, development and midgut enzymes of Helicoverpa armigera Hübner

Docking-Based Virtual Screening Ascertaining β-Sitosterol-Induced Alterations in the Helicoverpa armigera Hübner Gut Enzymes

The complete chloroplast genome sequence of Melochia corchorifolia Linnaeus, 1753 (Sterculiaceae)

Contact Info

Product

Resources

About