Efficacy of multi-groove silicone drains in single-port video-assisted thoracoscopic lung cancer surgery and their effect on C-reactive protein: a single-center experience

Abstract

Background: The purpose of this study was to systematically evaluate the effectiveness and safety of a multi-groove silicone drain in single-port video-assisted thoracoscopic lung cancer surgery and its effect on postoperative serum C-reactive protein (CRP) levels. Methods: We retrospectively analyzed 122 surgical cases who underwent standard lobectomy and lymph node dissection for primary lung cancer between May 2020 and December 2020. A total of 62 patients received 19-F multi-groove silicone drains (experimental group) and 60 patients received 24-F conventional chest drains (control group). According to the different thoracic drainage approaches, the clinical efficacy in the perioperative period, postoperative complications, and postoperative serum CRP levels were compared between the 2 groups. Results: In this study, thoracic drainage volume, the average visual analog scale (VAS) pain scores in incisions, the rate of primary healing at the site of incisions, and the pulmonary infection rate in the multigroove silicone drain group were significantly lower than those in the conventional chest drain group (P<0.05), but there was no significant difference in the average hospital stay time, arrhythmia rates, and chest tube removal time between the 2 groups. At postoperative day 1, the levels of serum CRP in the 2 groups were further increased (P>0.05), and the comparison between the 2 groups showed that the levels of serum CRP in the multi-groove silicone drain group at 72 h after the operation were significantly lower than those in the conventional drain group (P<0.05). Conclusions:Our results showed that a multi-groove silicone drain is feasible and relatively safe in singleport video-assisted thoracoscopic lung cancer surgery for most patients. However we should take cautious in those patients with higher susceptibility of postoperative active bleeding. In patients undergoing lung cancer surgery in the clinical treatment process, the use of a multi-groove silicone drain can improve the quality of life of patients. Due to a small number of included studies and unclear bias, the above results should be verified by high-quality, large-sample randomized controlled studies.

[Retracted] Perioperative Effect of Single‐Port Thoracoscopic Segmentectomy and Three‐Port Thoracoscopic Segmentectomy in the Treatment of Early Non‐Small‐Cell Lung Cancer

“…In the field of segmentectomy for early-stage NSCLC, the more traditional surgical method is the three-port method, including the observation port, the main operating port, and the auxiliary operating port [ 4 , 5 ]. Although this traditional surgical method had become more and more mature, but massive scholars have found that there were some defects in three-port thoracoscopic surgery, such as numbness or dyskinesia at the distal end of the chest wall, and pain in the auxiliary operating port of the back [ 6 , 7 ]. So, the single-port thoracoscopic technique came into being, and it was also a major breakthrough in the minimally invasive technique of thoracic surgery in recent years [ 8 ].…”

Nomogram Prediction Model Analysis of Risk Factors for Conversion to Thoracotomy after Thoracoscopic Resection of Lung Cancer and Prognostic Value of Lung Cancer

“…In recent years, with the serious air pollution and the gradual deterioration of the environment, the incidence of various lung diseases is on the rise, among which lung cancer has become one of the cancers with the highest incidence [ 4 ]. Data from the National Cancer Center showed that in 2020, the number of new lung cancer cases in China will reach 816,000, accounting for 17.9% of all cancers [ 5 ]. That is an average of 16 people getting sick every 10 minutes.…”