Efficacy of Nanosilver with Collagen Matrix Vs Povidone Iodine in Healing of Lower Limb Ulcers

Abstract

Background: Wounds expose a patient to serious hazards like wound infection, tissue destruction, disfiguring and disabling scars. Use of nanosilver with collagen matrix in infected wounds, ulcers, diabetic wounds, burns reduced morbidity and hospital stay with its early wound healing effect. To evaluate the effect of nanosilver with collagen matrix V/s povidone iodine on similar types of wounds. Methods: This prospective study included one hundred patients with different types of wounds who attended Department of Surgery, index medical college & hospital, indore from January 2015 to January 2017. The patients were divided into two groups. Group A where topical management and dressing was done using nanotrix and group B where topical management and dressing was done using povidone iodine. Results: A standard grading in terms of percentage decrease in wound size, peri wound oedema/ erythema, pus discharge and percentage increase in granulation, fibrin and epithelisation was noted in various types of wounds in both groups. Nanotrix treated wounds showed significant reduction in inflammation and earlier healing than those treated with povidon iodine. Conclusion: Nanotrix application was found to be safe having no pain and allergic manifestation.