Abstract. In recent years, there has been a significant increase in the number of cotton bollworm (Helicoverpa armigera Hb., 1808) due to changing climatic conditions, the covert life cycle of caterpillars and the formation of resistance in the populations to some of the commonly used insecticides. Experiments with tomato variety Pink Rock F1 grown in greenhouses to determine the biological activity of some products for plant protection against cotton bollworm were conducted at the “Maritsa” Vegetable Crops Research Institute – Plovdiv. The bioproducts Rapax, Dipel 2X, Helicovex, Neem Azal T/S and Sineis 480 SC have good effectiveness >77% towards cotton bollworm in the interval 7-14 days after treatment. The tested insecticides Lanate 25 WP, Coragen 20 SC 200 ml/ha, Exalt 25 SC, Voliam Targo 063 SC, Ampligo 150 ZC and Affirm 095 SG show very good biological activity (E>84%) 7-14 days after treatment.