Efficacy of neuromuscular electrical stimulation in patients with COPD followed in intensive care unit

Akar, Olcay; Günay, Ersin; Ulaşlı, Sevinç Sarınç; Ulaşlı, Alper Murat; Kaçar, Emre; Sarıaydın, Muzaffer; Solak, Okan; Çeli̇k, Sefa; Ünlü, Mehmet

doi:10.1111/crj.12411

Cited by 47 publications

(71 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Assessment of the risk of bias based on the method formulated by the Cochrane Collaboration showed that relative to the selection bias aspect of "random sequence generation", two studies exhibited a low risk of bias ( 23 , 25 ) and the other two an uncertain risk of bias. ( 26 , 27 ) Relative to the selection bias aspect of "allocation concealment", all four articles exhibited an uncertain risk of bias. ( 23 , 25 - 27 ) In regard to performance bias - "blinding of participants and professionals" - three studies exhibited an uncertain risk of bias ( 23 , 25 , 27 ) and one study presented a low risk of bias.…”

Section: Resultsmentioning

confidence: 99%

Safety of neuromuscular electrical stimulation among critically ill patients: systematic review

Sachetti

Carpes

Dias

et al. 2018

Revista Brasileira De Terapia Intensiva

View full text Add to dashboard Cite

ObjectiveTo review the evidence on the safety of neuromuscular electrical stimulation when used in the intensive care unit.MethodsA systematic review was conducted; a literature search was performed of the MEDLINE (via PubMed), PEDro, Cochrane CENTRAL and EMBASE databases, and a further manual search was performed among the references cited in randomized studies. Randomized clinical trials that compared neuromuscular electrical stimulation to a control or placebo group in the intensive care unit and reporting on the technique safety in the outcomes were included. Hemodynamic variables and information on adverse effects were considered safety parameters. Articles were independently analyzed by two reviewers, and the data analysis was descriptive.ResultsThe initial search located 1,533 articles, from which only four randomized clinical trials were included. Two studies assessed safety based on hemodynamic variables, and only one study reported an increase in heart rate, respiratory rate and blood lactate, without clinical relevance. The other two studies assessed safety based on reported adverse effects. In one, 15% of patients described a prickling sensation, without any clinically relevant abnormalities. In the other, one patient suffered a superficial burn due to improper parameter configuration.ConclusionNeuromuscular electrical stimulation is safe for critically ill patients; however, it should be applied by duly trained professionals and with proper evidence-based parameters.

show abstract

Section: Resultsmentioning

confidence: 99%

Safety of neuromuscular electrical stimulation among critically ill patients: systematic review

Sachetti

Carpes

Dias

et al. 2018

Revista Brasileira De Terapia Intensiva

View full text Add to dashboard Cite

show abstract

“…Of 25 full-text citations, nine studies with 276 participants fulfilled inclusive criteria to be reviewed. For papers excluded from this analysis, eight were due to study design,10,13,15,16,40–43 four were due to the fact that stimulation was acupuncture,44–47 three11,24,28 had insufficient or inapplicable data, and one25 reported on the same group of participants as in another paper 26Figure 1 describes the different phase of the search process.…”

Section: Resultsmentioning

confidence: 99%

Effectiveness of neuromuscular electrical stimulation for the rehabilitation of moderate-to-severe COPD: a meta-analysis

Chen¹,

Li²,

Guan³

et al. 2016

COPD

View full text Add to dashboard Cite

PurposePatients with COPD often experience skeletal muscle dysfunction. For those who are unable or unwilling to undertake physical training, neuromuscular electrical stimulation (NMES) may provide an alternative method of rehabilitation. The purpose of this meta-analysis was to investigate the controversial topic of whether this therapy is effective in patients with moderate-to-severe COPD.Patients and methodsWe pooled data from nine trials published between January 9, 2002 and January 4, 2016 across PubMed, Embase, Cochrane Central Register of Controlled Trials, Google Scholar, and relevant websites for randomized controlled trials. In these trials, patients with moderate-to-severe COPD were randomly allocated to receive NMES. Primary outcomes were quadricep strength and exercise capacity. The secondary outcome was health-related quality of life.ResultsWe extracted data from 276 patients. NMES contributed to statistically improved quadricep strength (standardized mean difference 1.12, 95% confidence interval [CI] 0.64–1.59, I2=54%; P<0.00001) and exercise capacity, including longer exercise distance (weighted mean difference 51.53, 95% CI 20.13–82.93, I2=90%; P=0.001), and longer exercise endurance (standardized mean difference 1.11, 95% CI 0.14–2.08, I2=85%; P=0.02). There was no significant difference in St George’s Respiratory Questionnaire scores (weighted mean difference −0.07, 95% CI −2.44 to 2.30, I2=56%; P=0.95).ConclusionNMES appears an effectual means of enhancing quadricep strength and exercise capacity in moderate-to-severe COPD patients. Further research is demanded to clarify its effect on other outcomes and determine the optimal parameters for an NMES program.

show abstract

“…Results showed that muscle strength (quadriceps femoris and vastus glutei) was significantly improved and days to move from bed to chair decreased in the group treated with NMES, with no safety concerns. More recently, Akar et al 92 showed similar results on muscle strength and, in addition, they demonstrated a reduction of the levels of inflammatory cytokines [C-reactive protein, interleukin (IL)-6, and IL-8) in patients treated with NMES. In this case, the stimulator generated symmetrical biphasic square 50-Hz waves and the amplitude was switched between 20 and 25 mA with 6 seconds of contraction, 1.5 seconds of increase, and 0.75 second of decrease.…”

Section: Neuromuscular Electrical Stimulationmentioning

confidence: 77%

Physical Therapy and Rehabilitation in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit

Martí

McWilliams

Gimeno‐Santos

2020

Semin Respir Crit Care Med

View full text Add to dashboard Cite

Chronic obstructive pulmonary disease (COPD) is a progressive lung condition that affects a person's ability to exercise and undertake normal physical function due to breathlessness, poor physical fitness, and muscle fatigue. Patients with COPD often experience exacerbations due to pulmonary infections, which result in worsening of their symptoms, more loss of function, and often require hospital treatment or in severe cases admission to intensive care units. Recovery from such exacerbations is often slow, and some patients never fully return to their previous level of activity. This can lead to permanent disability and premature death.Physical therapists play a key role in the respiratory management and rehabilitation of patients admitted to intensive care following acute exacerbation of COPD. This article discusses the key considerations for respiratory management of patients requiring invasive mechanical ventilation, providing an evidence-based summary of commonly used interventions. It will also explore the evidence to support the introduction of early and structured programs of rehabilitation to support recovery in both the short and the long term, as well as active mobilization, which includes strategies to minimize or prevent physical loss through early retraining of both peripheral and respiratory muscles.

show abstract

Efficacy of neuromuscular electrical stimulation in patients with COPD followed in intensive care unit

Cited by 47 publications

References 28 publications

Safety of neuromuscular electrical stimulation among critically ill patients: systematic review

Safety of neuromuscular electrical stimulation among critically ill patients: systematic review

Effectiveness of neuromuscular electrical stimulation for the rehabilitation of moderate-to-severe COPD: a meta-analysis

Physical Therapy and Rehabilitation in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit

Contact Info

Product

Resources

About