Efficacy of Oral Clonidine as Premedication on Intraoperative Bleeding and Consumption of Inhalational Agent in Patients Undergoing Functional Endoscopic Sinus Surgery

Chakole, Vivek; Shankar, Shilpa; Sneha, Kota; Sen, Jyotsna; Madavi, Sheetal; Vaishnav, Devavrat

doi:10.9734/jpri/2021/v33i47a33041

Cited by 2 publications

(1 citation statement)

References 1 publication

(1 reference statement)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…found mean MAC (%) of sevoflurane consumption was less in clonidine group (1.25 ± 0.25) in comparison to multivitamin group (1.30 ± 0.20) in patients undergoing FESS surgery. [ 21 ]…”

Section: Discussionmentioning

confidence: 99%

Target-Controlled Inhalational Anesthesia-Isoflurane Consumption with Adequacy of Anesthesia Monitoring in Conventional and Multimodal Analgesia – A Comparative Study

Vithayathil

Savitha

Dixit

et al. 2022

Anesthesia Essays &Amp; Researches

View full text Add to dashboard Cite

Background: In a time of increased concern over the environmental impact of chlorofluorocarbons, there is an impetus to minimize inhalational anesthetic consumption. It is possible with multimodal analgesia (MMA) and the use of end-tidal controlled anesthesia (EtCA) which is a low-flow anesthesia technique with adequacy of anesthesia (AoA) monitoring. In MMA, all four elements of pain processing namely transduction, transmission, modulation, and perception are targeted with drugs having a different mechanism of action. In EtCA, anesthetic gases are automatically adjusted for the set minimal alveolar concentration by newer anesthesia work station (GE Healthcare Aisys CS2). AoA is a derived parameter of entropy and surgical pleth index which measures the depth of anesthesia and analgesia, respectively. Aim: The aim is to assess the difference in isoflurane consumption between MMA and conventional groups for a given period of time with EtCA and AoA monitoring. Setting and Design: This was a prospective randomized controlled trial involving 60 patients undergoing laparoscopic cholecystectomy. They were divided into MMA group and conventional group. Materials and Methods: Both the groups received preemptive intravenous diclofenac sodium 75 g and 2% xyloadrenaline infiltration at entry ports. MMA group in addition received paracetamol 1 g and clonidine 0.75 μg.kg − 1 . Intraoperatively, patients were on EtCA with AoA monitoring. Statistical Analysis: Mean differences in isoflurane consumption between the two groups were compared using an independent t -test. Postextubation adverse effects of analgesic drugs and awareness under general anesthesia were compared using the Chi-square test and presented as numbers and percentages. P < 0.05 was considered a statistically significant. Results: Mean isoflurane consumption in the conventional group was 12.7 ± 5.3 mL which was significantly higher than the MMA group which was 8.9 ± 4.1 mL ( P = 0.002). The duration of anesthesia between the groups was not significant clinically ( P = 0.931). Conclusion: EtCA with MMA significantly reduces isoflurane consumption compared to the conventional group of anesthesia.

show abstract

“…found mean MAC (%) of sevoflurane consumption was less in clonidine group (1.25 ± 0.25) in comparison to multivitamin group (1.30 ± 0.20) in patients undergoing FESS surgery. [ 21 ]…”

Section: Discussionmentioning

confidence: 99%

Target-Controlled Inhalational Anesthesia-Isoflurane Consumption with Adequacy of Anesthesia Monitoring in Conventional and Multimodal Analgesia – A Comparative Study

Vithayathil

Savitha

Dixit

et al. 2022

Anesthesia Essays &Amp; Researches

View full text Add to dashboard Cite

show abstract

Public risk perceptions, emotions and behaviours under a major epidemic: A structural equation model analysis

Wang

Zhang

Feng

2022

Journal of Advanced Nursing

View full text Add to dashboard Cite

As one part of a larger project, this manuscript has been shared the same database with another manuscript entitled Public risk perception, emotion and coping behaviour under the COVID-19 pandemic: An instrument development study. And we have submitted this methodology paper to another journal and is currently under review by peer reviewers. Although two manuscripts share the same database, they are different in terms of the study purpose as well as the study methodology. Regarding the study purpose: this study aimed to explore the relationship between public risk perceptions, emotions and behaviours, whereas the other one aimed to develop the study instruments and to evaluate their psychometric properties.Regarding the study methodology: this study used an advanced statistical method called the structural equation modelling to explore the interactions between public risk perceptions, emotions and behaviours. While the other one employed the exploratory factor analysis, confirmatory factor analysis and others to evaluate the newly developed research instruments.

show abstract

Efficacy of Oral Clonidine as Premedication on Intraoperative Bleeding and Consumption of Inhalational Agent in Patients Undergoing Functional Endoscopic Sinus Surgery

Cited by 2 publications

References 1 publication

Target-Controlled Inhalational Anesthesia-Isoflurane Consumption with Adequacy of Anesthesia Monitoring in Conventional and Multimodal Analgesia – A Comparative Study

Target-Controlled Inhalational Anesthesia-Isoflurane Consumption with Adequacy of Anesthesia Monitoring in Conventional and Multimodal Analgesia – A Comparative Study

Public risk perceptions, emotions and behaviours under a major epidemic: A structural equation model analysis

Contact Info

Product

Resources

About