Efficacy of orally administered praziquantel against Zeuxapta seriolae and Benedenia seriolae (Monogenea) in yellowtail kingfish Seriola lalandi

Williams, Rissa E.; Ernst, Ingo; Chambers, Clinton B.; Whittington, Ian D.

doi:10.3354/dao01824

Cited by 51 publications

(69 citation statements)

References 22 publications

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“…Praziquantel has already been demonstrated to be effective against monogenean parasites (e.g. Schmahl & Mehlhorn 1985, Fajer-Avila et al 2007, Williams et al 2007, and it is logical that it was effective against another platyhelminth worm; however, the cyst wall might slow down transmission of the drug to the parasite, explaining why 2 injections were necessary to stop the infection. …”

Section: Discussionmentioning

confidence: 99%

Turbellarian black spot disease in bluespine unicornfish Naso unicornis in New Caledonia, caused by the parasitic turbellarian Piscinquilinus sp.

Justine¹,

Leblanc²,

Keller³

et al. 2009

Dis. Aquat. Org.

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Turbellarian black spot disease is described in a bluespine unicornfish Naso unicornis (Perciformes, Acanthuridae) collected from the wild off Nouméa, New Caledonia, South Pacific. Each cyst contained a whitish worm, 2 to 4 mm in length, which was able to swim freely in seawater. Cyst walls consisted of fibrous tissue with a scattering of melanocytes. Worms had 2 eyespots at the anterior end, a pharynx at the posterior end and a largely undeveloped reproductive system. They were identified as Piscinquilinus sp. (= Ichthyophaga sp.), a genostomatid turbellarian. The disease spread within 2 wk from a single infected fish to 3 other unicornfish in the same tank, in spite of copper sulphate and diluted seawater treatment; however, other fish from several families kept in the same tank were not infected, suggesting specificity of these parasites. Praziquantel injections into the infected fish eliminated the infection. Other cases of turbellarian infections are reported from 7 fish species off New Caledonia; prevalence is very low (0.3%).KEY WORDS: Black spot disease · Fish · Naso unicornis · Turbellaria · New Caledonia · Piscinquilinus · Ichthyophaga Resale or republication not permitted without written consent of the publisher

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Section: Discussionmentioning

confidence: 99%

Turbellarian black spot disease in bluespine unicornfish Naso unicornis in New Caledonia, caused by the parasitic turbellarian Piscinquilinus sp.

Justine¹,

Leblanc²,

Keller³

et al. 2009

Dis. Aquat. Org.

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“…al. 2004, Williams et al 2007. Until now, oral application at this dosage in elasmobranchs has not been investigated.…”

Section: Discussionmentioning

confidence: 99%

Heterocotyle tokoloshei sp. nov. (Monogenea, Monocotylidae) from the gills of Dasyatis brevicaudata (Dasyatidae) kept in captivity at Two Oceans Aquarium, Cape Town, South Africa: Description and notes on treatment

Vaughan¹,

Chisholm²

2010

Acta Parasitologica

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Heterocotyle tokoloshei sp. nov. is described from the gills of a single Short-tail stingray, Dasyatis brevicaudata, kept in captivity at the Two Oceans Aquarium in Cape Town, South Africa. The stingray exhibited laboured gill ventilation and deteriorating health on exhibit and was removed to the quarantine area for parasitological study and treatment. A 12 h bath treatment of praziquantel at 20mg/l, pre-dissolved in ethanol, removed 3084 parasites from the gills of the ray. However, the presence of a large number of eggs 24 h post-treatment indicated that viable egg laying adults remained on the gills and that the treatment was not 100% effective. Praziquantel was subsequently administered orally by intubation to the same ray at 150 mg/kg under anaesthetic (2-phenoxyethanol at 0.15 ml/l for approximately 1 h), which resulted in the removal of approximately 392 000 parasites from the gills 12 h post-oral treatment. Twenty-four h post-oral treatment, 3383 worms, but no eggs were recovered. No worms or eggs were recovered 48 h to 10 days post-oral treatment. The ray died approximately 30 days after the completion of the treatment. Heterocotyle tokoloshei sp. nov. is the first Heterocotyle species described from South Africa and represents the first record of a pathogenic Heterocotyle species. The new species can be distinguished from the other 16 species in the genus by the distal region of the male copulatory organ which has distinct small spines and by the morphology of the male copulatory organ accessory piece. Eggs of H. tokoloshei sp. nov. are laid singly and hatch spontaneously between 5 and 8 days at 18°C.

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“…On Day 8 of each experiment, fish were anaesthetised, weighed and sampled for flukes using a method modified from Williams et al (2007). All fish were firstly anaesthetised (30 mg l −1 AQUI-S, www.…”

Section: Sampling and Data Analysismentioning

confidence: 99%

“…Issues relating to the palatability of PZQ have been reported and constrain its use. PZQ is known to be very bitter (Meyer et al 2009), and appetite suppression and diet rejection has been reported in S. quinqueradiata, S. dumerili (see Hirazawa et al 2004) and S. lalandi (see Williams et al 2007). If palatability problems can be overcome, PZQ has great potential as a cost-effective and easily administered treatment against such flukes.…”

Section: Introductionmentioning

confidence: 99%

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Praziquantel form, dietary application method and dietary inclusion level affect palatability and efficacy against monogenean parasites in yellowtail kingfish

2014

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The bitterness of racemic praziquantel (PZQ) currently constrains its use as an infeed treatment against monogenean flukes in finfish aquaculture. In an effort to increase the palatability of diets containing racemic PZQ for yellowtail kingfish, the palatability and efficacy of 2 forms of racemic PZQ (powder or powder within microcapsules) against natural infestations of skin and gill flukes were compared using 2 different dietary application methods (incorporated within the pellet mash prior to extrusion or surface-coated after extrusion) at active dietary inclusion levels of 8, 16 and 25 g kg −1 in large (3.5−4 kg) yellowtail kingfish. There was no clear benefit of incorporating PZQ into diets prior to extrusion. PZQ microcapsules improved the palatability of PZQ-containing diets but did not completely mask the bitter flavour. At the lowest active dietary inclusion level of 8 g kg −1 , ingestion of the diet containing PZQ microcapsules was equal to the control and significantly better than that containing PZQ powder. At an inclusion level of 16 g kg −1, ingestion of the PZQ microcapsule diet was significantly better than that containing the same inclusion of PZQ powder but significantly lower than the control. Consumption of the diet containing 25 g kg −1 of PZQ microcapsules was poor. All fish consuming medicated feeds had a significant reduction in flukes relative to control fish; however, efficacy data and blood serum analysis suggested that diets containing PZQ microcapsules had lower bioavailability than those containing PZQ powder.

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Efficacy of orally administered praziquantel against Zeuxapta seriolae and Benedenia seriolae (Monogenea) in yellowtail kingfish Seriola lalandi

Cited by 51 publications

References 22 publications

Turbellarian black spot disease in bluespine unicornfish Naso unicornis in New Caledonia, caused by the parasitic turbellarian Piscinquilinus sp.

Turbellarian black spot disease in bluespine unicornfish Naso unicornis in New Caledonia, caused by the parasitic turbellarian Piscinquilinus sp.

Heterocotyle tokoloshei sp. nov. (Monogenea, Monocotylidae) from the gills of Dasyatis brevicaudata (Dasyatidae) kept in captivity at Two Oceans Aquarium, Cape Town, South Africa: Description and notes on treatment

Praziquantel form, dietary application method and dietary inclusion level affect palatability and efficacy against monogenean parasites in yellowtail kingfish

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