Efficacy of Organic Selenium from Se-Enriched Yeast on Selenium Transfer from Sows to Piglets

Svoboda, Martin; Ficek, Radek; Drábek, J.

doi:10.2754/avb200877040515

Cited by 25 publications

(21 citation statements)

References 17 publications

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“…Such response occurred despite the fact that the present basal dietary Se level was largely higher than the basal level found in cereals grown in Se-deficient soils (Mahan et al 2005) and also higher than the NRC (1998, 2012) recommendations of 0.15 mg/kg. The Se source effect on whole blood Se concentration of gilts is consistent with previous reports (Schrauzer 2000, Svoboda et al 2008, Fortier et al 2012. The absorbed MSe is converted into functional selenoproteins containing selenocysteine (Sec), with slight storage in organs (Windisch 2002).…”

Section: Discussionsupporting

confidence: 89%

Gene expression of porcine blastocysts from gilts fed organic or inorganic selenium and pyridoxine

Dalto¹,

Tsoi²,

Audet³

et al. 2015

Reproduction

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In this study, we determined how maternal dietary supplementation with pyridoxine combined with different sources of selenium (Se) affected global gene expression of porcine expanded blastocysts (PEB) during pregnancy. Eighteen gilts were randomly assigned to one of the three experimental diets (nZ6 per treatment): i) basal diet without supplemental Se or pyridoxine (CONT); ii) CONTC0.3 mg/kg of Na-selenite and 10 mg/kg of HCl-pyridoxine (MSeB 6 10); and iii) CONTC0.3 mg/kg of Se-enriched yeast and 10 mg/kg of HCl-pyridoxine (OSeB 6 10). All gilts were inseminated at their fifth post-pubertal estrus and killed 5 days later for embryo harvesting. A porcine embryospecific microarray was used to detect differentially gene expression between MSeB 6 10 vs CONT, OSeB 6 10 vs CONT, and OSeB 6 10 vs MSeB 6 10. CONT gilts had lower whole blood Se and erythrocyte pyridoxal-5-P concentrations than supplemented gilts (P!0.05). No treatment effect was observed on blood plasma Se-glutathione peroxidase activity (PZ0.57). There were 10, 247, and 96 differentially expressed genes for MSeB 6 10 vs CONT, OSeB 6 10 vs CONT, and OSeB 6 10 vs MSeB 6 10 respectively. No specific biological process was associated with MSeB 6 10 vs CONT. However, for OSeB 6 10 vs CONT, upregulated genes were related with global protein synthesis but not to selenoproteins. The stimulation of some genes related with monooxygenase and thioredoxin families was confirmed by quantitative real-time RT-PCR. In conclusion, OSeB 6 10 affects PEB metabolism more markedly than MSeB 6 10. Neither Se sources with pyridoxine influenced the Se-glutathione peroxidase metabolic pathway in the PEB, but OSeB 6 10 selectively stimulated genes involved with antioxidant defense.

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Section: Discussionsupporting

confidence: 89%

Gene expression of porcine blastocysts from gilts fed organic or inorganic selenium and pyridoxine

Dalto¹,

Tsoi²,

Audet³

et al. 2015

Reproduction

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“…In our study, the average daily growth of piglets was greatly increased in the selenomethionine-treated group. However, many literatures reported that maternal Se-enriched yeast intake showed little effect to improve the growth performance of its offspring when compared with inorganic Se resource [9,10,21,22]. We concluded that selenomethionine exhibited higher efficiency on absorption and utilization efficiency than Se-enriched yeast and sodium selenite, and could provide one of the effective additives for sows to improve the growth performance of piglets before weaning.…”

Section: Discussionmentioning

confidence: 83%

“…1). Some studies indicated that serum GSH-Px activity of piglets was not affected by the supplemental maternal Se source, although greater transfer of Se to their progeny was observed [8,10,21], while Gunter et al [22] reported that feeding seleno-yeast in cows significantly increased the GSH-Px activity in calves at birth than sodium selenite, and GSH-Px activity in calves nursing cows fed seleno-yeast does not seem to significantly differ from calves nursing cows fed sodium selenite. In the present study, selenomethionine greatly improved the antioxidant status in the organs of piglets.…”

Section: Discussionmentioning

confidence: 99%

Selenomethionine: an Effective Selenium Source for Sow to Improve Se Distribution, Antioxidant Status, and Growth Performance of Pig Offspring

Zhan

YanZhao

Wang

et al. 2010

Biol Trace Elem Res

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The present study was to investigate the efficiency of maternal selenomethionine intake on growth performance, Se distribution, and antioxidant status of pig offspring by comparing with sodium selenite. A total of 12 sows (Landrace × Yorkshire) with same pregnancy were randomly divided into two groups; each group was replicated six times. These two groups received the same basal gestation and lactation diets containing 0.04 mg Se/kg, supplemented with 0.3 mg Se/kg sodium selenite and selenomethionine (i.e., seneno-DL: -methylseleno), respectively. The feeding trial lasted for 60 days, with 32 and 28 days for gestation and lactation period, respectively. Compared with sodium selenite, maternal selenomethionine intake significantly (p < 0.05) increased the daily weight gain of piglet from birth to weaning. The Se concentration in the colostrum and milk and tissue Se content of piglets were significantly higher (p < 0.05) in the selenomethionine-treated group. The antioxidant status was greatly improved in piglets of selenomethionine-treated group and was illuminated by the increased total antioxidant capability, glutathione peroxidase, superoxide dismutase, and glutathione, and decreased the malondialdehyde level in the organs of piglets. The increased (p < 0.05) triiodothyronine (T(3)) and decreased (p < 0.05) thyroxine (T(4)) concentration indicated the improved protein synthesis and energy production in the selenomethionine-treated group. The increased (p < 0.05) pancreatic digestive enzymes of protease, amylase, and lipase activities indicated that maternal selenomethionine intake may have a positive effect on the degradation and absorption of nutrients in its piglets. In summary, we concluded that maternal selenomethionine intake increased Se deposition, antioxidant status, and nutrient use efficiency, thus providing an effective way to improve the growth performance of piglets from birth to weaning.

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“…Prenatal Se supplementation provides an effective antioxidant system that is already in place at the time of birth, while postnatal Se supplementation becomes the main determinant of progeny Se status after the first few days of progeny life [24]. Many literatures reported that maternal Se-enriched yeast intake showed little effect to improve the growth performance of its pig offspring, when compared with inorganic Se resource [14,25,26]. Wang [27] Se concentration (µg/ml) suggested Se from organic sources was more available than inorganic selenium for growth.…”

Section: Discussionmentioning

confidence: 99%

Effect of Different Selenium Sources on Productive Performance, Serum and Milk Se Concentrations, and Antioxidant Status of Sows

Wang

Zhan

et al. 2010

Biol Trace Elem Res

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The experiment was conducted to study the effects of different selenium (Se) sources on productive performance, serum and milk Se concentrations, and antioxidant status of sows. A total of 12 sows (Landrace×Yorkshire) with same pregnancy were randomly divided into two groups; each group was replicated six times. These two groups received the same basal gestation and lactation diets containing 0.042 mg Se/kg, supplemented with 0.3 mg Se/kg sodium selenite or selenomethionine (i.e., seneno-DL: -methylseleno), respectively. The feeding trial lasted for 60 days, with 32 and 28 days for gestation and lactation period, respectively. Compared with sodium selenite, maternal selenomethionine intake significantly increased (P < 0.05) the weaning litter weight and average weight of piglet. The Se concentration in the serum, colostrum, and milk of sows were significantly higher (p < 0.05) in the selenomethionine-treated group. The antioxidant status was greatly improved in sows of selenomethionine-treated group and was illuminated by the increased total antioxidant capability (T-AOC; P < 0.05) and decreased malondialdehyde (MDA; P < 0.01) level in the serum of sows, increased T-AOC (P < 0.05), glutathione (GSH) peroxidase (P < 0.05), superoxide dismutase (P < 0.05) and GSH (P < 0.05), and MDA (P < 0.05) level in the colostrum and milk of sows. These results suggested that maternal selenomethionine intake improved Se concentration and antioxidant status of sows, thus maintain maternal health and increase productive performance after Se was transferred to its offspring.

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Efficacy of Organic Selenium from Se-Enriched Yeast on Selenium Transfer from Sows to Piglets

Cited by 25 publications

References 17 publications

Gene expression of porcine blastocysts from gilts fed organic or inorganic selenium and pyridoxine

Gene expression of porcine blastocysts from gilts fed organic or inorganic selenium and pyridoxine

Selenomethionine: an Effective Selenium Source for Sow to Improve Se Distribution, Antioxidant Status, and Growth Performance of Pig Offspring

Effect of Different Selenium Sources on Productive Performance, Serum and Milk Se Concentrations, and Antioxidant Status of Sows

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