Efficacy of Ozonised Water and 0.2% Chlorhexidine Gluconate in the Management of Chronic Periodontitis when Used as an Irrigant in Conjugation with Phase I Therapy

Abstract

Aim:To evaluate the efficacy of irrigation of periodontal pockets by using ozonated water and 0.2% chlorhexidine (CHX) gluconate as adjuncts to scaling and root planing in the management of chronic periodontitis. Materials and methods:For the present study, 20 patients in the age group of 30-60 years, suffering from chronic periodontitis presenting with at least one site with an almost similar pocket depth of 4-6 mm in both the quadrants of maxillary arch was taken. Irrigation was done after 2 weeks of scaling and root planning on the same day with ozonated water and 0.2% chlorhexidine gluconate for two and half minutes. The clinical parameters like gingival index, probing pocket depth (PPD) and clinical attachment level (CAL) were recorded for both the groups at the baseline visit.They were subsequently recalled after 4 weeks and 3 months interval from the baseline visit. Data thus collected was compiled and put to statistical analysis.

Effectiveness of ozone therapy in the treatment of periodontal diseases: a systematic review

“…Samples were analyzed using the BANA-Zyme™ processor to assess periodontal pathogens of the "red complex". time varied widely from seconds (20-45) to minutes (1)(2)(3)(4)(5)(6)(7)(8)(9)(10). Only in the study by Isler et al [29], surgical treatment for peri-implantitis was performed, and Amoxicillin (500mg) and Metronidazole (500mg) every 8 hours for 7 days were prescribed.…”

“…Subgingival irrigation with antiseptics is described in literature mainly with the use of water, saline solution, povidone iodine, hydrogen peroxide, and chlorhexidine gluconate. The latter is the substance most used for this purpose, as it is an antiseptic with broad bactericidal spectrum, with bacteriostatic and antifungal function, and is also effective against gram-positive and -negative aerobic and anaerobic bacteria, [9,10]. However, it also causes mucosal desquamation, damage to the healing of lesions, fixation of fibroblasts on root surfaces, changes in taste and tooth color [7].…”

Revisiting Oral Antiseptics, Microorganism Targets and Effectiveness

“…In periodontitis patients, despite the combination of CHX mouthwashes and mechanical debridement, it is possible that subgingival biofilm and calculus remain in the deep pockets [ 113 , 122 ]. A solution to this problem might be a new developing method that consists of the local delivery of antibacterial agents into periodontal pockets [ 123 , 124 ]. However, there are still no significant improvements with this procedure when added to non-surgical periodontal treatment [ 122 ].…”

Use of Ozone in Veterinary Dentistry as an Alternative to Conventional Antibiotics and Antiseptics

“…Depending on the concentration and the exposure time (>1 min), it is productive against pathogenic microorganisms, such as P. gingivalis and Streptococcus mutans [21,22]. The induction of initial chemical-physical damage of the components of the cell wall, pursued in the sensitive species and not provided with an endogenous antioxidant system, may inactivate the microorganism by the oxidation of all the essential components (enzymes, proteins, DNA, RNA) [26][27][28].…”