Efficacy of Prophylactic use of Antibiotics to Avoid Flare up During Root Canal Treatment of Nonvital Teeth: A Randomized Clinical Trial

Akbar, Iftikhar

doi:10.7860/jcdr/2015/12046.5620

Cited by 10 publications

(19 citation statements)

References 31 publications

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“…[31] To prevent flare-ups: The precautionary measures for root canal flare-up comprise of choosing instrumentation technique with the minimal extrusion of periapical debris, completion of the biomechanical preparation in a single visit, sealing of the access cavity between visits, and maintaining aseptic environment during RCT. [32] However, some studies recommended the systemic use of antibiotics to prevent flare up during or after RCT. [2833] Some consider that instituting antibiotics before the commencement of RCT in teeth with necrotic pulps is therapeutic rather than prophylactic.…”

Section: Discussionmentioning

confidence: 99%

“…[35] However, studies show that prophylactic use of amoxicillin in asymptomatic nonvital teeth before RCT has no effect on the incidence of flare-up. [3236] Prophylaxis for patients at risk: The AAE guidelines recommend that prophylactic antibiotics should be given for immunocompromised patients, or with a history of infective endocarditis or placement of a prosthetic joint in previous 2 years, and patients with congenital heart disease. [37] Antibiotic prophylaxis is not right for everyone and should only be used when the potential benefits outweigh the risks of taking them.…”

Section: Discussionmentioning

confidence: 99%

“…[35] However, studies show that prophylactic use of amoxicillin in asymptomatic nonvital teeth before RCT has no effect on the incidence of flare-up. [3236]…”

Section: Discussionmentioning

confidence: 99%

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Antibiotic abuse during endodontic treatment: A contributing factor to antibiotic resistance

Bansal

Jain

Goyal

et al. 2019

J Family Med Prim Care

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Antibiotic resistance is one of our most serious global health threats. The adverse effects of overusing and misusing antibiotics are highly publicized in the health professional literature. Antibiotic abuse occurs during routine endodontic treatment and there are deficiencies in knowledge regarding prescribing antibiotic and appropriate prophylactic antibiotic use. Multidisciplinary coordination and cooperation among dentists, pharmacists, and patients is needed to curb antibiotic abuse. As endodontists, we can become part of the solution to the antibiotic resistance crisis and deal with it conclusively. This review article discusses antibiotic resistance resulting from antibiotic abuse during endodontic treatment, various factors contributing to it, and measures required for stopping antibiotic abuse in endodontic treatment. A web-based research on MedLine was performed with terms Review Articles published in the last 10 year's dental journals in English for literature researching, extracting, and synthesizing data. Relevant articles were shortlisted. Important cross-reference articles were also reviewed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Antibiotic abuse during endodontic treatment: A contributing factor to antibiotic resistance

Bansal

Jain

Goyal

et al. 2019

J Family Med Prim Care

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“…In cases of trauma, there is presence of internal resorption with abscess formation. (Akbar, 2015).Trauma to the anterior teeth with the underlying esthetic, psychosocial, functional, and therapeutic problems adversely affect an individual's quality of life. (Andreasen, Andreasen and Andersson, 2018) Diagnosis for a non vital tooth is done by clinical and radiographic examination.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of non-vital teeth with various endodontic pathologies-a retrospective study

Prashaanthi¹,

Nasim²,

.K.K³

2021

cibg

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Most of the time non-vital teeth are associated with various pathologies. The early intervention would save the teeth from its loss. Depending on the etiology and the duration, the pathology differs among the non-vital teeth. The aim of this study was to evaluate non-vital teeth with various endodontic pathologies. This retrospective study included patients who were diagnosed with non-vital teeth from July 2019 to March 2020 in a dental hospital. The case records of all patients were retrieved which included the clinical , radiographic examination and treatment done for the patients. Variables such as age, gender, any associated endodontic pathologies were retrieved from the case sheets. Data was tabulated and was subjected to statistical package IBM SPSS version 20.0.Around 80,000 patients were reviewed and 238 patients met the inclusion criteria.Out of 238 patients, 71.8% were males and 28.2% were females.On analysing the prevalence of non vital teeth among different age groups, 21-30 years age group (32.8%) were more affected. On comparing the non vital teeth with endodontic pathology ,non-vital teeth without periapical lesion (74.4%) were found to be in a higher prevalence. Among non-vital teeth with endodontic pathology, periapical abscess (14.3%) was found to have higher prevalence followed by periapical cyst (2.9%) and calcified canal (2.9%).On analysing the prevalence of non vital teeth among gender , males (71.8%) were more affected. No statistically significant association was found between age, gender and non vital teeth. (p>0.05).Within the limitation of the study, the prevalence of non-vital teeth without periapical lesion were found to be higher. Among non-vital teeth with endodontic pathology, the most common pathology was chronic periapical abscess.Males were more affected with non vital teeth and had higher prevalence among the 21-30 years age group.

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“…4,16 Gram negative anaerobic bacterias are commonly responsible for the development of post-operative symptoms. 17 Amoxicillin was used in this study because it is effective against bacteria commonly present in the root canal system. It provides high serum level initially and is maintained for 10 to 12 hours thus making it excellent choice for single dose regime.…”

Section: Introductionmentioning

confidence: 99%

Comparing the effect of Placebo and Prophylactic Antibiotics on asymptomatic Necrotic teeth.

Qasim

Anjum

Yousaf

et al. 2019

TPMJ

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Objectives: Treatment of asymptomatic necrotic teeth is a common type of occurrence in endodontic practice. Root canal treatment of these teeth sometimes results in pain and /or swelling of varying degree. These severe symptoms upset both the patient and dentist. This study was to compare the effect of prophylactic amoxicillin and placebo in endodontic flare-up in asymptomatic necrotic teeth requiring root canal treatment. This was evaluated by using flare-up index. The influence of age, sex, was compared between flare-up and non-flare-up groups. Using a standardized technique and the same materials eliminated the variability of operator. Study Design: Quasi experimental study. Setting: Department of Operative Dentistry, Lahore Medical and Dental College, Lahore. Period: From January 2018 to December 2018. Material & Methods: 102 patients with asymptomatic necrotic teeth with periapical radiolucency were selected from the Operative Dentistry Department of Lahore Medical and Dental College. Patients were divided into two groups experimental and control, by convenient sampling. One half of the patients were given prophylactic amoxicillin and other half was given placebo one hour before treatment. Results: Flare-up occurred in four of the experimental and seven of the control group patients. Statistical analysis revealed no significant differences between flare-up and non- flare- up patients for age and sex. The data outcome was of qualitative in nature i.e. pain and swelling, they were subjected to Chi-Square test of significance with P value of £0.05. The results demonstrated that 10.8% of the 102 patients had a flare-up. No side effects were observed in the patients who were prescribed amoxicillin. Conclusion: The occurrence of flare-up did not significantly influence by Prophylactic amoxicillin (P= .33).

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Efficacy of Prophylactic use of Antibiotics to Avoid Flare up During Root Canal Treatment of Nonvital Teeth: A Randomized Clinical Trial

Cited by 10 publications

References 31 publications

Antibiotic abuse during endodontic treatment: A contributing factor to antibiotic resistance

Antibiotic abuse during endodontic treatment: A contributing factor to antibiotic resistance

Evaluation of non-vital teeth with various endodontic pathologies-a retrospective study

Comparing the effect of Placebo and Prophylactic Antibiotics on asymptomatic Necrotic teeth.

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