Efficacy of Regular Exercise During Pregnancy on the Prevention of Postpartum Depression

Coll, Carolina de Vargas Nunes; Domingues, Marlos Rodrigues; Stein, Alan; Silva, Bruna Gonçalves Cordeiro da; Bassani, Diego G.; Hartwig, Fernando Pires; Silva, Inácio Crochemore Mohnsam da; Silveira, Mariângela Freitas da; Silva, Shana Ginar da; Bertoldi, Andréa Dâmaso

doi:10.1001/jamanetworkopen.2018.6861

Cited by 69 publications

(76 citation statements)

References 34 publications

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“…The majority of the reviewed studies found a negative association of PA with MH, and positive for physical inactivity studies. There are two studies [ 30 , 31 ] that found no association of PA with MH, and a third that found association with depression symptoms, but no association for patients with anxiety [ 32 ].…”

Section: Resultsmentioning

confidence: 99%

“…Of the 27 studies included in this review, 14 (51.8%) were cross-sectional studies, 2 RCTs, and 11 follow-ups of a cohort. Different PA measures were assessed: 6 programmes of PA reporting an objective measure of PA [ 30 , 31 , 36 , 44 , 46 , 47 ], and the remaining 21 offering conclusions from studies based on self-reported PA. The included studies were critically assessed and their main focus was on finding an association of different types of PA with objective/clinically relevant symptoms for MH [ 31 , 39 , 41 , 46 , 47 ].…”

Section: Resultsmentioning

confidence: 99%

“…Finally, 1 study found a beneficial but only for women [ 31 ]. Two studies did not find an association of PA with MH [ 30 , 31 ].…”

Section: Resultsmentioning

confidence: 99%

“…3.3.3. Differences in the Association of PA with MH for Self-Reported and Objective Types of PA Among the 27 studies reviewed and analysed, four assessed impact on MH with an objective measure of PA [30,31,36,46]. Objective measures of PA included supervised exercise programmes, accelerometer/activity monitor, and bouldering psychotherapy.…”

Section: Differences In the Association Of Pa With Mh Between Self-reported And Objectivementioning

confidence: 99%

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The Association of Physical (in)Activity with Mental Health. Differences between Elder and Younger Populations: A Systematic Literature Review

Maynou

Hernández-Pizarro

Rodríguez³

2021

IJERPH

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Background: Physical activity is associated with mental health benefits. This systematic literature review summarises extant evidence regarding this association, and explores differences observed between populations over sixty-five years and those younger than sixty-five. Methods: We reviewed articles and grey literature reporting at least one measure of physical activity and at least one mental disorder, in people of all ages. Results: From the 2263 abstracts screened, we extracted twenty-seven articles and synthesized the evidence regarding the association between physical (in)activity and one or more mental health outcome measures. We confirmed that physical activity is beneficial for mental health. However, the evidence was mostly based on self-reported physical activity and mental health measures. Only one study compared younger and elder populations, finding that increasing the level of physical activity improved mental health for middle aged and elder women (no association was observed for younger women). Studies including only the elderly found a restricted mental health improvement due to physical activity. Conclusions: We found inverse associations between levels of physical activity and mental health problems. However, more evidence regarding the effect of ageing when measuring associations between physical activity and mental health is needed. By doing so, prescription of physical activity could be more accurately targeted.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Finally, 1 study found a beneficial but only for women [ 31 ]. Two studies did not find an association of PA with MH [ 30 , 31 ].…”

Section: Resultsmentioning

confidence: 99%

Section: Differences In the Association Of Pa With Mh Between Self-reported And Objectivementioning

confidence: 99%

See 2 more Smart Citations

The Association of Physical (in)Activity with Mental Health. Differences between Elder and Younger Populations: A Systematic Literature Review

Maynou

Hernández-Pizarro

Rodríguez³

2021

IJERPH

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“…As both breastfeeding and physical activity are beneficial it would be reasonable to expect that mothers might want to do both [12]. There is some evidence for associations between physical activity during pregnancy and longer-term postpartum weight loss, lower rates of depression, improved quality of life, and longer breastfeeding [13,14,15]. Although there has been extensive research on the independent benefits of physical activity and breastfeeding for both mothers and infants, the association between these important issues has only rarely been studied [12,15].…”

Section: Introductionmentioning

confidence: 99%

Physical Activity During Pregnancy is Associated with Improved Breastfeeding Outcomes: A Prospective Cohort Study

Nguyen

Binns

Nguyen

et al. 2019

IJERPH

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Physical activity is important for health, but little is known about associations between physical activity during pregnancy and breastfeeding. The aim of this study was to investigate any association between antenatal physical activity and breastfeeding duration. A prospective cohort of 2030 Vietnamese women, recruited between 24 and 28 week-gestation was followed up to twelve months postpartum. Physical activity was determined using the pregnancy physical activity questionnaire at baseline interview. Data was available for 1715 participants at 12 months, a 15.5% attrition rate. At 12 months 71.8% of mothers were still breastfeeding. A total of 20.9% women met physical activity targets and those mothers undertaking higher levels of physical activity had a lower risk of breastfeeding cessation by twelve months [hazard ratios HR = 0.59 (95% CI 0.47–0.74), p < 0.001, and HR = 0.74 (0.60–0.92), p = 0.006; respectively] when compared to the lowest tertile. Similarly, women with increased levels of physical activity have higher rates of breastfeeding at twelve months, compared to the lowest level [odds ratio OR = 1.71 (95% CI 1.29–2.25) and 1.38 (1.06–1.79)]. Higher levels of physical activity by pregnant women are associated with improved breastfeeding outcomes.

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Perioperative Adjunctive Esketamine for Postpartum Depression Among Women Undergoing Elective Cesarean Delivery

Chen,

Guo,

et al. 2024

JAMA Netw Open

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ImportancePostpartum depression (PPD) is one of the most common mental health conditions during the perinatal and postpartum periods, which can have adverse effects on both mother and infant.ObjectiveTo investigate the efficacy of perioperative adjunctive esketamine administration after cesarean deliveries in the prevention of PPD.Design, Setting, and ParticipantsA single-center, double-blind, placebo-controlled, randomized clinical trial was conducted from January 1, 2022, to January 1, 2023, at Fujian Provincial Hospital among 298 women aged 18 to 40 years, with an American Society of Anesthesiologists grade I to III classification and singleton full-term pregnancies who were scheduled for elective cesarean deliveries. Primary analyses were performed on a modified intention-to-treat basis.InterventionsPatients were randomly assigned to the esketamine (n = 148) and control (n = 150) groups. Those in the esketamine group received a single intravenous injection of 0.25 mg/kg of esketamine immediately after fetal delivery, followed by 50 mg of esketamine as an adjuvant in patient-controlled intravenous analgesia for 48 hours after surgery. Saline was given to the control group of patients.Main Outcomes and MeasuresThe primary outcome was assessments of PPD symptoms by using the Edinburgh Postnatal Depression Scale (EPDS) at postpartum day 7. Positive screening for PPD was defined as a score of 10 or more points on the EPDS. In addition, the EPDS was analyzed as a continuous variable to evaluate depressive symptoms. Secondary outcomes included the Numeric Rating Scale (NRS) of postoperative pain, along with safety evaluations including adverse events and clinical assessments at postpartum days 14, 28, and 42.ResultsA total of 298 pregnant women were included, with 150 in the control group (median age, 31.0 years [IQR, 29.0-34.0 years]) and 148 in the esketamine group (median age, 31.0 years [IQR, 28.0-34.0 years]). The prevalence of depression symptoms was significantly lower among patients given esketamine compared with controls (23.0% [34 of 148] vs 35.3% [53 of 150]; odds ratio, 0.55; 95% CI, 0.33-0.91; P = .02) on postpartum day 7. In addition, the esketamine group also showed a significantly lower change in EPDS scores (difference of least-squares means [SE], −1.17 [0.44]; 95% CI, −2.04 to −0.31; effect size, 0.74; P = .008). However, there were no differences between the groups in the incidence of positive screening results for PPD or in changes from the baseline EPDS scores at postpartum days 14, 28, and 42. There were no differences in NRS scores at rest and on movement except on movement at 72 hours postoperatively, when scores were significantly lower in the esketamine group (median, 3.0 [IQR, 2.0-3.0] vs 3.0 [IQR, 3.0-3.5]; median difference, 0 [95% CI, 0-0]; P = .03).Conclusions and RelevanceThese results suggest that intravenous administration of esketamine during the perioperative period of elective cesarean delivery can improve depression symptoms during the early postpartum period. However, this antidepression effect may not be universally applicable to patients with low EPDS scores.Trial RegistrationChinese Clinical Trial Registry Identifier: ChiCTR2100054199

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Efficacy of Regular Exercise During Pregnancy on the Prevention of Postpartum Depression

Cited by 69 publications

References 34 publications

The Association of Physical (in)Activity with Mental Health. Differences between Elder and Younger Populations: A Systematic Literature Review

The Association of Physical (in)Activity with Mental Health. Differences between Elder and Younger Populations: A Systematic Literature Review

Physical Activity During Pregnancy is Associated with Improved Breastfeeding Outcomes: A Prospective Cohort Study

Perioperative Adjunctive Esketamine for Postpartum Depression Among Women Undergoing Elective Cesarean Delivery

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