Efficacy of Sciatic Nerve Mobilization in Lumbar Radiculopathy due to Prolapsed Intervertebral Disc

Yamin, Faisal; Musharraf, Hira; Rehman, Atiq Ur; Aziz, Saima

doi:10.5958/0973-5674.2016.00009.5

Cited by 4 publications

(4 citation statements)

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“…The repeated and selective nerve tensioning or flossing techniques, of which NDT consists, are non-pharmacological treatments able to modulate pain and, in particular, mechanical neuropathic pain in humans and animals [ 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. NDT has been demonstrated to induce pro-regenerative effects by promoting the neuritis outgrowth and cell differentiation in sensory and motor neurons in vitro in a dose-dependent manner and preventing apoptosis only in sensory neurons [ 44 ].…”

Section: Discussionmentioning

confidence: 99%

“…The selective repeated administration of uniaxial tensions to somatic nerves, also known as neurodynamic treatment (NDT), has shown to be effective in pain modulation and nerve conduction improvements detected by electrophysiological assessment in long term neuropathic pain patients suffering from carpal tunnel syndrome [ 28 , 29 , 30 , 31 ] and radiculopathies of somatic nerves in the upper or lower limbs [ 32 , 33 , 34 , 35 , 36 , 37 ]. NDT significantly reduces pain and disability with long-term effects in neuropathic pain patients.…”

Section: Introductionmentioning

confidence: 99%

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Neurodynamic Treatment Promotes Mechanical Pain Modulation in Sensory Neurons and Nerve Regeneration in Rats

et al. 2022

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Background: Somatic nerve injuries are a rising problem leading to disability associated with neuropathic pain commonly reported as mechanical allodynia (MA) and hyperalgesia. These symptoms are strongly dependent on specific processes in the dorsal root ganglia (DRG). Neurodynamic treatment (NDT), consisting of selective uniaxial nerve repeated tension protocols, effectively reduces pain and disability in neuropathic pain patients even though the biological mechanisms remain poorly characterized. We aimed to define, both in vivo and ex vivo, how NDT could promote nerve regeneration and modulate some processes in the DRG linked to MA and hyperalgesia. Methods: We examined in Wistar rats, after unilateral median and ulnar nerve crush, the therapeutic effects of NDT and the possible protective effects of NDT administered for 10 days before the injury. We adopted an ex vivo model of DRG organotypic explant subjected to NDT to explore the selective effects on DRG cells. Results: Behavioural tests, morphological and morphometrical analyses, and gene and protein expression analyses were performed, and these tests revealed that NDT promotes nerve regeneration processes, speeds up sensory motor recovery, and modulates mechanical pain by affecting, in the DRG, the expression of TACAN, a mechanosensitive receptor shared between humans and rats responsible for MA and hyperalgesia. The ex vivo experiments have shown that NDT increases neurite regrowth and confirmed the modulation of TACAN. Conclusions: The results obtained in this study on the biological and molecular mechanisms induced by NDT will allow the exploration, in future clinical trials, of its efficacy in different conditions of neuropathic pain.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Neurodynamic Treatment Promotes Mechanical Pain Modulation in Sensory Neurons and Nerve Regeneration in Rats

et al. 2022

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“…The study also showed that mobilization of nerve was really effective in enhancing the mobility of nerve and improving SLR range. 20 Hanney et al reported that use of an neural mobilization through oscillating SLR help in increasing pain-free range of hip flexion. 21 Another study conducted by Adel et al also reported that neural mobilization is helpful in the reduction of disability, improving discomfort, and centralization of symptom.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of bent leg raise technique and neurodynamics in patients with radiating low back pain

et al. 2021

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Objective: To compare the effectiveness of bent leg raise technique and neurodynamics in patients with low back pain that radiates up to the knee. Methods: The pre-test post-test control group study was conducted at Department of Physical therapy, Maqsood Medical Complex and General Hospital Peshawar from February to July 2019. Patients with radiating low back pain of both genders aged 18-60 years were included in the study. Patients were divided into Group-A and Group-B. Group-A patients received Mulligan bent leg raise technique while Group-B patients received neurodynamics. Both groups received five sessions per week, for four weeks. Numeric pain rating scale, Oswestry disability index and goniometer was used to assess pain, functional disability and straight leg raise range before and after the interventions. Data was analyzed using SPSS version 20. Results: Thirty-two participants with mean age of 38.81±9.94 years, participated in the study. There were no significant differences (P-value >0.05) between the two groups at baseline. Post-treatment, within Group-Analysis showed that all three variables (pain, functional disability and straight leg raise range) significantly (P<0.05) improved in both groups. However, post treatment between Group-Analysis showed that there were no significant differences (P>0.05) between the two groups. Conclusion: Both neurodynamics and bent leg raise technique significantly improved pain, functional disability and straight leg raise range in patients with low back pain that radiates up to the knee. However, there were no significant differences between the groups who received either neurodynamics or bent leg raise technique. doi: https://doi.org/10.12669/pjms.38.1.4010 How to cite this:Adnan M, Arsh A, Ali B, Ahmad S. Effectiveness of bent leg raise technique and neurodynamics in patients with radiating low back pain. Pak J Med Sci. 2022;38(1):---------. doi: https://doi.org/10.12669/pjms.38.1.4010 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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“…Neurodynamic mobilization is very effective in reducing symptoms and limitations in discogenic sciatica (19). It signi cantly reduced sciatic pain and restored sciatic nerve mobility (20,21). The current work took a step in getting an evidence of the best treatment modalities in the management of sciatica and its related disabilities.…”

Section: Introductionmentioning

confidence: 99%

Effects of Slider, Tensioner Neurodynamic Mobilization Techniques and Stretching Exercises in patient with Chronic Discogenic Sciatica: A randomized, single blinded Comparative Study

Morsi

Nahass

Ibrahim

2022

Preprint

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Objective: To compare the effectiveness of the slider, tensioner neurodynamic mobilization techniques and stretching exercises on pain, ROM, and functional disability in patients with chronic discogenic sciatica.Design: A pre-test post-test three-armed comparative study designSetting: Outpatient clinics, faculty of physical therapy, Kafrelsheikh UniversityParticipants: 36 patients with unilateral chronic discogenic sciatica were randomly allocated into three equal groups: Group (A) slider neurodynamic mobilization Group (B) tensioner neurodynamic mobilizationGroup (C) stretching exercises of back extensors, hamstrings, and gastrocnemius musclesTreatment was given three sessions per week for two weeks.Outcome measures: all patients were examined by Visual Analogue scale (VAS) for pain intensity, Modified-Modified Schober test (MMST) for lumbar flexion ROM, Goniometer for hip flexion and knee extension ROM, and Oswestry Disability Index (ODI) for functional assessment. Results: there were no statistically significant differences between groups at baseline (p<0.05). There were statistically significant differences in the slider and tensioner groups compared to the stretching group for all variables. Furthermore, statistically significant differences were found in the slider technique as compared to the tensioner technique regarding ROM of lumbar flexion (p = 0.03), hip flexion (p = 0.004), and knee extension (p = 0.005). Conclusion: Slider and tensioner neurodynamic mobilization techniques are more effective than stretching exercises in terms of reducing pain, increasing ROM, and improving function. Slider technique is more effective in ROM improvement.

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Efficacy of Sciatic Nerve Mobilization in Lumbar Radiculopathy due to Prolapsed Intervertebral Disc

Cited by 4 publications

References 0 publications

Neurodynamic Treatment Promotes Mechanical Pain Modulation in Sensory Neurons and Nerve Regeneration in Rats

Neurodynamic Treatment Promotes Mechanical Pain Modulation in Sensory Neurons and Nerve Regeneration in Rats

Effectiveness of bent leg raise technique and neurodynamics in patients with radiating low back pain

Effects of Slider, Tensioner Neurodynamic Mobilization Techniques and Stretching Exercises in patient with Chronic Discogenic Sciatica: A randomized, single blinded Comparative Study

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