“…Numerous methods have been tried to control medfly populations, including chemical products, such as malathion and other organophosphate insecticides (4,8), classic biological control programs based on the release of some of parasitoids and predators (38,41,44), toxic baits (2,13,31,32,35,56), mass trapping systems (24,51), the sterile insect technique (7,34,61,63,72,73), and development of integrated strategies of management (71). In spite of all of these attempts, control of Mediterranean fruit fly populations has been ineffective, and losses associated with this pest worldwide are constantly increasing (21,46).…”