Efficacy of Tokishakuyakusan add‐on therapy with low‐dose oral contraceptive pills on endometriosis patients with dysmenorrhea

Taniguchi, Fuminori; Tokita, Yohei; Ota, Ikuko; Yamane, Emiko; Komatsu, Hiroaki; Azuma, Yukihiro; Sato, Eri; Endo, Yusuke; Sunada, Hiroshi; Harada, Tasuku

doi:10.1111/jog.14424

Cited by 5 publications

(2 citation statements)

References 17 publications

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“…The MSQ is a generic women-health PROM tool and not endometriosis-specific. Two observational studies have been published using this tool [ 35 , 36 ]; however, none have validated this questionnaire for endometriosis.…”

Section: Resultsmentioning

confidence: 99%

Patient-Reported Outcome Measures in Endometriosis

Nicolas‐Boluda¹,

Oppenheimer

Bouaziz³

2021

JCM

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Patient Reported Outcome Measures (PROM) evoke measurements that allow capturing patients’ perspectives on their condition. In endometriosis care, physicians’ understanding of the effect of the disease and the treatment on patients is often poor. The use of PROMs in endometriosis clinical practice can facilitate patient-provider communication and the implementation of patient-centered care, improve patients’ quality of life, as well as provide a tool for patients’ self-management of the disease. Today, PROMs are extensively used in research and clinical trials, however they are barely used in clinical practice. The development of digital tools facilitating capturing PROMs can contribute to their use by physicians in routine endometriosis care. However, all PROMs are not adapted to be used in routine care in the context of endometriosis. The objective of this study was to present a catalogue of available PROMs for routine endometriosis care and evaluate them according to selected criteria. To do so, we explored the different PROMs currently in the literature. Consequently, 48 PROM were identified as tools used to evaluate various dimensions of the impact of endometriosis on patients. The selected PROMs were evaluated for their potential to be used as a standard in clinical practice in endometriosis. The selected catalogue of PROMs is the starting point for the integration of digital tools to capture PROMs and the development of patient-centered dashboards to be used by patients and clinicians in endometriosis care and self-management to improve care processes, patient satisfaction, quality of life, and outcomes.

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Section: Resultsmentioning

confidence: 99%

Patient-Reported Outcome Measures in Endometriosis

Nicolas‐Boluda¹,

Oppenheimer

Bouaziz³

2021

JCM

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“…Kampo medicines, such as tokishakuyakusan, kamishoyosan, and keishibukuryogan, are commonly prescribed for Japanese women ( 4 ). Tokishakuyakusan in particular has been shown to be effective for dysmenorrhea ( 9 , 10 ). In addition, Kampo medicines, including tokishakuyakusan and saireito, may improve live birth rate among women with recurrent pregnancy loss ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database

et al. 2021

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Introduction: Traditional Japanese (Kampo) medicines are often prescribed for women in Japan before, during, and after pregnancy. However, detailed information on the actual frequency of use and safety of Kampo preparations during pregnancy is lacking.Aim: To investigate the frequency of prescription of Kampo medicines for pregnant women in Japan.Methods: Information on Kampo medicines prescribed during outpatient care and hospitalization of selected mothers from January 2005 to August 2016 were extracted from the Japan Medical Data Center (Tokyo, Japan), which is a large claims database.Results: Of the 33,941 subscribers identified from the database, 16,294 (48%) received at least one prescription of a Kampo medicine. Kakkonto was the formula most prescribed during the study period, followed by shoseiryuto and tokishakuyakusan. In the 180 days before pregnancy, the most prescribed medicine was tokishakuyakusan, followed by kakkonto and shoseiryuto. Shoseiryuto, tokishakuyakusan, and kakkonnto were the formulae most prescribed during pregnancy. The most prescribed medicines during the 180 days postpartum were kakkonto, shoseiryuto, and saireito.Conclusions: Information in the Japanese insurance system shows that Kampo medicines are often prescribed during pregnancy. Most of these prescriptions are generally used for the treatment of common cold. Tokishakuyakusan in particular is usually used in the treatment of various symptoms of pregnancy. Further research is needed to clarify the relationship between the use of Kampo medicines during pregnancy and adverse events in infants in Japan.

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