Efficacy of Toothpastes on Bacteria Isolated from Oral Cavity

Bhattacharjee, Satabdi; Nath, Soumitra; Bhattacharjee, Prisweta; Chouhan, Manasi; Deb, Bibhas

doi:10.5530/ijmedph.2018.2.19

Cited by 10 publications

(11 citation statements)

References 21 publications

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“…Bhattacharjee evaluated the antibacterial activity of toothpastes with different properties and reported that herbal toothpastes are more effective than fluoride- and triclosan-containing toothpastes [30]. According to the comparison of antibacterial activity of the toothpastes tested, Splat Organic and Splat Biocalcium without essential oil addition showed similar diameter inhibition zones to Colgate Total against S. mutans ( p < 0.05) (Table 3).…”

Section: Discussionmentioning

confidence: 99%

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Antibacterial Activities of Herbal Toothpastes Combined with Essential Oils against Streptococcus mutans

et al. 2019

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In recent years, people have become more conscious about the side-effects of fluoride toothpastes and herbal products have drawn attention as alternatives in the struggle against caries. Studies have focused on the benefits of essential oils obtained from herbs because of their antibacterial effects. The aim of this study was to evaluate and compare the antibacterial activity of Origanum dubium and Cinnamomum cassia oils combined with herbal toothpastes against Streptococcus mutans. The antibacterial activity of the test materials was determined using the agar well diffusion method before and after the addition of essential oils. We tested the efficacy of Splat Organic and Splat Biocalcium against S. mutans (12 mm and 11 mm, respectively) doubled in combination with Origanum dubium (23 mm for both toothpastes) and tripled with Cinnamomum cassia (38 mm and 36 mm, respectively). Jack N’ Jill toothpaste, which did not initially show any antibacterial effect, exhibited the largest inhibition zones after the addition of the essential oils (38 mm for Origanum dubium and 39 mm for Cinnamomum cassia). The results of this study pointed out that herbal toothpastes exhibit statistically higher antibacterial activity against Streptococcus mutans (p < 0.05) than their initial forms after the addition of essential oils.

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Section: Discussionmentioning

confidence: 99%

“…There are some studies in the literature comparing fluoride-containing toothpastes and herbal toothpastes [29,30]. Due to their antimicrobial effects, essential oils may be used to prevent dental caries.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activities of Herbal Toothpastes Combined with Essential Oils against Streptococcus mutans

et al. 2019

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“…Sodium fluoridesodium laurylsulfate and sodium fluoridepotassium nitrate toothpastes did not show inhibitory activity against S. aureus, S. mitis, S. salivarius, but both toothpastes inhibited S. pyogenes. The low inhibition potential of sodium fluoride-sodium laurylsulfate toothpaste compared to other toothpastes is supported by Bhattcharjee et al [37]. All toothpastes contain sodium laurysulfate (SLS) in their constitution, except sodium fluoride-potassium nitrate toothpaste.…”

Section: Discussionmentioning

confidence: 94%

Antibacterial Potentials of some Toothpaste Products against some Oral Bacterial Isolates

Oluboyo

Charles

Akele

et al. 2021

BDS

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Objetive: Manufacturers of toothpastes claim that their products are active against oral microbiome capable of causing tooth decay. The objective of this study was to investigate the manufacturers’ claim using some of the toothpaste products sold in Ado-Ekiti, Nigeria. Material and methods: The antibacterial potentials of five commercialized toothpaste products (designated sodium fluoride-zinc sulphate, benzyl alcohol-sodium fluorophosphate, sodium fluoride-eugenol, sodium fluoridesodium laurylsulfate and sodium fluoridepotassium nitrate) were tested against six oral isolates of dental caries and periodontal origin – Staphylococcus aureus, Streptococcus mitis, Streptococcus salivarius, Streptococcus pyogenes and Pseudomonas aeruginosa. The antimicrobial potentials were evaluated using modified agar well diffusion method. Various dilutions of the toothpaste products from 1:1 to 1:16 were tested against each test microorganism. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the toothpastes were determined. Results: sodium fluoride-zinc sulphate, benzyl alcoholsodium fluorophosphate and sodium fluorideeugenol toothpastes showed inhibitory effects on S. aureus, S. mitis and S. salivarius. Sodium fluoride-sodium laurylsulfate and sodium fluoride-potassium nitrate toothpastes showed no inhibitory effect on the organisms except S. pyogenes. Only sodium fluoride-potassium nitrate toothpaste inhibited E. coli while none of the toothpastes inhibited P. aeruginosa. The MIC and MBC of sodium fluoride-zinc sulphate, benzyl alcohol-sodium fluorophosphate, and sodium fluoride-eugenol toothpastes showed bacteriostatic and bactericidal effects on the organisms. Sodium fluoride-zinc sulphate, benzyl alcohol-sodium fluorophosphate, and sodium fluoride-eugenol toothpastes showed comparable effects on S. aureus, S. mitis and S. salivarius. Sodium fluoride-eugenol toothpaste was strongest against S. mitis, benzyl alcoholsodium fluorophosphates toothpaste was strongest against S. pyogenes, sodium fluoridezinc sulphate toothpaste was strongest against S. salivarius and only sodium fluoride-potassium nitrate toothpaste inhibited E. coli. Conclusion: The manufacturer’s claim is upheld by this study for sodium fluoride-zinc sulphate, benzyl alcohol-sodium fluorophosphate and sodium fluoride-eugenol toothpastes. However, sodium fluoride-sodium laurylsulfate and sodium fluoride-potassium nitrate toothpastes showed limited inhibitory potentials. Keywords Antibacterial; Caries; Oral isolates; Periodontitis; Toothpastes.

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“…Similarly, Unani formulations like Sunoon Zard , Sunoon Mulook, Sunoon Mujalli etc. have been shown effective anti-bacterial, anti-inflammatory and analgesic effect and are prescribed in the treatment of oro-facial diseases [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…In sight of above some novel phototherapeutic compounds have been developed and investigated for its efficacy [ 3 , 4 ]. Herbal toothpastes are reported to have a good antibacterial activity and are safer as compared to fluoride - and triclosan-containing toothpastes [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Study of antimicrobial activity of Unani poly herbal toothpaste “Sunoon Zard”

Parveen

Ahmad

Rashid

et al. 2021

Heliyon

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Objective The present study was envisioned to develop Sunoon Zard a traditional Unani toothpowder into toothpaste form along with its physicochemical standardization and evaluation of anti microbial activity against oral pathogens by in vitro study. Materials and methods Herbal extracts based powder was redesigned to toothpaste as per the Pharmacopoeial guidelines and its pharmaceutical evaluation was conceded as per the Indian Government Tooth Paste Specifications. In vitro study was done to evaluate the antibacterial activity by using agar well diffusion method against dental pathogens. Zone of Inhibition was taken as the end parameter against the test pathogens after appropriate incubation period. It was compared with Dimethyl sulphoxide (DMSO) used as solvent (0.01%) as Negative control whereas Ciprofloxacin 5μg/disk (standard antibiotic for gram positive) and Gentamicin 10μg/disk (standard antibiotic for gram negative) were used as Positive control. All the experiment was done as per the Clinical and Laboratory Standards Institute (CLSI) Guidelines in triplicates. Results Sunoon Zard was developed into toothpaste form and its physicochemical values were found to in consonance with the optimum values as mentioned in Bureau of Indian Standard. In vitro study of the Sunoon Zard toothpaste was found to be effective against various dental pathogens with specific sensitivity with good zone of inhibition towards gram negative bacterial strains viz. P.aeruginosa and K.pneuomoniae while among gram positive a significant inhibition was found against C.xerosis and S.viridans . Conclusion The developed toothpaste from classical Unani herbal tooth powder will provide the better patient compliance. Moreover its scientific screening which exhibited potential antibacterial activity in controlling pathogenic oral microflora compared to the standard drugs also revalidated the claim of Unani Physicians that the Sunoon Zard is quite effective in various oro-dental disorders.

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Efficacy of Toothpastes on Bacteria Isolated from Oral Cavity

Cited by 10 publications

References 21 publications

Antibacterial Activities of Herbal Toothpastes Combined with Essential Oils against Streptococcus mutans

Antibacterial Activities of Herbal Toothpastes Combined with Essential Oils against Streptococcus mutans

Antibacterial Potentials of some Toothpaste Products against some Oral Bacterial Isolates

Study of antimicrobial activity of Unani poly herbal toothpaste “Sunoon Zard”

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