Efficacy of transcutaneous electrical nerve stimulation versus biofeedback training on bladder and erectile dysfunction in patients with spinal cord injury

Shendy, Wael; Semary, Moataz; Battecha, Kadrya H.; Abdel-Azim, Mohamed; Mourad, Husam S; Gohary, Amira M. El

doi:10.4103/1110-1083.162044

Cited by 13 publications

(21 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of these, six RCTs met the inclusion criteria. A total of 353 individuals, 165 in TENS groups and 188 controls were included in these RCTs as shown in Table 1 (15)(16)(17)(18)(19)(20). There were 60 females (17%) and 293 males (83%).…”

Section: Search Resultsmentioning

confidence: 99%

Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials

Parittotokkaporn

Varghese

O’Grady

et al. 2021

Neuromodulation: Technology at the Neural Interface

View full text Add to dashboard Cite

Section: Search Resultsmentioning

confidence: 99%

Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials

Parittotokkaporn

Varghese

O’Grady

et al. 2021

Neuromodulation: Technology at the Neural Interface

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

“…Electrodes could be placed adjacent to the sacral region (S3), tibial region, clitoral or penile region, or into the vagina or rectum. The sacral or tibial region was likely the most logical site since it directly or indirectly targets the medullar root S3, and the latter was often be preferred as a minimally invasive modality due to the poor tolerability of intra-vaginal and intraanal electrodes resulting from pain or discomfort (37,(41)(42)(43). In 3 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 4 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 5 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) (2.1%) 3 (7.7%) 0 (0%) 3 (7.7%) 0 (0%) 0 (0%) 3 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 4 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 5 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 3 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 4 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 5 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 4 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 5 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) ) 0 (0%) 0 (0%) 0 (0%) 1 (2.7%) 4 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 5 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) EQ-5D score 0.975 ± 0.11 0.940 ± 0.12 0.32 1.000 ± 0.05 1.000 ± 0.09 0.14 1.000 ± 0.00 1.000 ± 0.06 0.01…”

Section: Discussionmentioning

confidence: 99%

Long-Term Effect of Early Post-operative Transcutaneous Electrical Stimulation on Voiding Function After Radical Hysterectomy: A Multicenter, Randomized, Controlled Trial

Gao

Wang

et al. 2021

Front. Med.

View full text Add to dashboard Cite

Introduction: Post-radical-hysterectomy (RH) patients suffer from a series of problems resulting from neurovascular injury, such as bladder dysfunction, which reduce their quality of life. We have designed this study to evaluate the efficacy of transcutaneous electrical stimulation (TENS) on patient rehabilitation after RH for early cervical cancer.Materials and methods: A total of 97 patients were enrolled in a randomized-controlled trial (from January 2015 to December 2019) involving 7 medical centers nationwide. Patients were assigned to either the intervention group (n = 46), or the control group (n = 51). TENS was given to patients in the intervention group from the 7th day after surgery for a total of 14–21 days. The control group received no TENS. Primary outcomes were measured for residual urine volume and recovery of urination function. Secondary outcomes were measures for urodynamics (UDS), pelvic floor electromyography function examination (PFEmF), and quality of life (QoL).Results: Residual urine volume and improvement in the rate of urination were found to show no significant differences on the 14th, 21st, and 28th days after surgery. The maximum flow rate (Qmax) in the intervention group was significantly higher than that in the control group on the 28th day, but there were no significant differences in average flow rate, voiding time, time to Qmax, muscle fiber strength, muscle fiber fatigue, and the abnormal rate of A3 reflection on the 28th day and the 3rd mo., as well as in the QoL at 3rd mo., 6th mo., and 12th mo. after surgery.Conclusion: Our study showed no sufficient evidence to prove that TENS under the trialed parameters could improve the subject's voiding function, PFEmF, and QOL after RH. This has provided valuable data for rehabilitation after RH.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT02492542.

show abstract

“…The authors concluded that TENS of pelvic floor muscles was a promising, safe, effective, and inexpensive physical therapy technique to improve urinary and erectile function in patients with partial suprasacral SCI (26). No undesirable effects were reported for TENS 45 …”

Section: Performance and Safety Of Treatments Available For Sci Patientsmentioning

confidence: 99%

“…No undesirable effects were reported for TENS. 45 Another drug-based option is the intraurethral insertion of an Alprostadil pellet before sexual intercourse. The compound is absorbed through the urethra into the corpora cavernosa, thus increasing the intracellular levels of cAMP, that leads to a reduction in intracellular Ca 2+ levels, finally inducing smooth muscle relaxation and consequent tumescence.…”

Section: Other Treatmentsmentioning

confidence: 99%

Performance and safety of treatment options for erectile dysfunction in patients with spinal cord injury: A review of the literature

et al. 2020

View full text Add to dashboard Cite

Background For a large proportion of patients with spinal cord injury, sexuality and reproduction are important issues. However, sparse data exist regarding available treatment options for this patient population. Objectives We sought to review performance and safety rates of all currently available treatment options for erectile dysfunction in spinal cord injury men. Materials and methods A systematic literature review without time restrictions was performed using PubMed/EMBASE database for English‐, Italian‐, German‐, and Spanish‐language articles. Articles' selection was performed according to the PRISMA guidelines. Relevant papers on erectile dysfunction in spinal cord injury patients were included in the final analyses. Results and Discussion Overall, 47 studies were eligible for inclusion in this review. Of these, most evidence dealt with phosphodiesterase 5‐inhibitors and intracavernous drug injection. Both treatment options are associated with high levels of performance and with patients/partners' satisfaction; side effects are acceptable. Overall, penile prostheses and vacuum erection devices are in general less approved by spinal cord injury patients and are correlated with increased rates of complications in comparison with phosphodiesterase 5‐inhibitors and intracavernous drug injection. Sacral neuromodulation, transcutaneous electrical nerve stimulation, and intraurethral suppositories have been poorly studied, but preliminary studies did not show convincing results. Conclusion The best treatment options for erectile dysfunction in spinal cord injury patients emerged to be phosphodiesterase 5‐inhibitors and intracavernous drug injection. The choice of erectile dysfunction treatment should be based on several aspects, including residual erectile function, spinal cord injury location, and patients' comorbidities. Future studies assessing the applicability of less well‐studied treatments, as well as evaluating innovative options, are needed in this specific population.

show abstract

Efficacy of transcutaneous electrical nerve stimulation versus biofeedback training on bladder and erectile dysfunction in patients with spinal cord injury

Cited by 13 publications

References 3 publications

Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials

Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials

Long-Term Effect of Early Post-operative Transcutaneous Electrical Stimulation on Voiding Function After Radical Hysterectomy: A Multicenter, Randomized, Controlled Trial

Performance and safety of treatment options for erectile dysfunction in patients with spinal cord injury: A review of the literature

Contact Info

Product

Resources

About