Efficacy of Transcutaneous Electrical Nerve Stimulation in Children with Overactive Bladder Refractory to Pharmacotherapy

Malm‐Buatsi, Elizabeth; Nepple, Kenneth G.; Boyt, Margaret A.; Austin, J. Christopher; Cooper, Christopher S.

doi:10.1016/j.urology.2007.06.1109

Cited by 59 publications

(50 citation statements)

References 17 publications

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“…Earlier uncontrolled studied reported improvement and cure rates of OAB or lower urinary tract dysfunction from 56-100%. 64,65 Two sham-controlled studies showed similar results, 66,67 as has a 2015 uncontrolled study reporting complete and partial response rates of 70 and 22%, respectively. 68 Recently, two groups compared TENS to approved treatment options for OAB in children.…”

Section: Neuromodulationmentioning

confidence: 75%

Overactive bladder in children

Ramsay¹,

Bolduc²

2017

CUAJ

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Overactive bladder (OAB) is a highly prevalent disorder in the pediatric population. This condition is especially troublesome for pediatric patients and their families when associated with incontinence, since it negatively affects self-esteem and impairs children's development. From the patient's perspective, urgency and urge incontinence can have a significant impact, negatively affecting their quality of life. For a therapy to have true benefit, changes must not only be statistically significant, but must also be perceived as meaningful by the patient. A stepwise approach is favoured to treat this pathology, starting with behavioural therapy, followed by medical management, and eventually more invasive procedures.Antimuscarinic agents are the mainstay of medical treatment for OAB. Oxybutynin is the most commonly used antimuscarinic in the pediatric population. However, some patients have a suboptimal response to antimuscarinics and many experience bothersome side effects, which have been documented with all antimuscarinics to a significantly higher degree than placebo. Although there have been reports about the use of tolterodine, fesoterodine, trospium, propiverine, and solifenacin in children, to date, only oxybutynin has been officially approved for pediatric use by medical authorities in North America. This review will address alternative treatment options for pediatric patients presenting with OAB, from conservative measures to more invasive therapies.

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Section: Neuromodulationmentioning

confidence: 75%

Overactive bladder in children

Ramsay¹,

Bolduc²

2017

CUAJ

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“…Bower et al [27] implemented this technique in the suprapubic or sacral anterior roots regions of children with non-neurogenic bladders and reported continence improvement in 73% of cases with an increase in the mean volume voided. Malm-Buatsi et al [28] showed improved daytime continence in 73% of cases in children with nonneurogenic OAB resistant to treatment and disappearance of urgency in all patients treated by transcutaneous PTNS.…”

Section: Discussionmentioning

confidence: 96%

Management of refractory overactive bladder in children by transcutaneous posterior tibial nerve stimulation: A controlled study

Boudaoud¹,

Binet²,

Line³

et al. 2015

Journal of Pediatric Urology

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“…Değişik hasta gruplarında değişik yöntem ve parametrelerle uygulanan çalışmalar mevcuttur (3,6,7,22,23,(27)(28)(29)(30)(31). Omurilik hasarlı 22 hastada yapılan bir çalışmada, akım frekansı 50 Hz, impuls süresi 200 mikrosaniye, akım şiddeti 15-20 mA, stimülasyon süresi 15 dakika olarak ayarlanmış, 30 seans tedavi uygulanmış ve mesane fonksiyonlarında (maksimum sistometrik kapasitede artış, rezidüel idrar miktarında azalma) belirgin iyileşme bildirilmiştir (30 uygulanan SDTENS tedavisi ile mesane kapasitesinde istatistiksel olarak anlamlı artış sağlanırken, aynı süreyle sadece antikolinerjik tedavi alan hastalarda, kapasitedeki artış anlamlılık sınırına ulaşmamıştır, buna karşılık meydana gelen değişim miktarları karşılaştırıldığında, gruplar arasında istatistiksel olarak anlamlı fark olmadığı gözlenmiştir.…”

Section: Discussionunclassified