1998
DOI: 10.1016/s0015-0282(98)00177-0
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Efficacy of treatment for unexplained infertility

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Cited by 267 publications
(139 citation statements)
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“…Recent studies exploring the efficacy of clomiphene citrate as a treatment for infertile women have provided equivocal results. In 1998 Guzick et al performed a retrospective review of the literature of women receiving clomiphene citrate +/− intrauterine insemination (IUI), and found the pregnancy rate was 6-8 % per cycle, compared to 2-4 % when not treated [26]. On the contrary, a recent large prospective study which randomised 600 women with unexplained infertility to clomiphene citrate, IUI or expectant management showed comparable results for all three arms in terms of delivery rates [27].…”
Section: Ovulation Induction With Clomiphene Citrate and Intrauterinementioning
confidence: 99%
“…Recent studies exploring the efficacy of clomiphene citrate as a treatment for infertile women have provided equivocal results. In 1998 Guzick et al performed a retrospective review of the literature of women receiving clomiphene citrate +/− intrauterine insemination (IUI), and found the pregnancy rate was 6-8 % per cycle, compared to 2-4 % when not treated [26]. On the contrary, a recent large prospective study which randomised 600 women with unexplained infertility to clomiphene citrate, IUI or expectant management showed comparable results for all three arms in terms of delivery rates [27].…”
Section: Ovulation Induction With Clomiphene Citrate and Intrauterinementioning
confidence: 99%
“…Although fertile men as a group have higher mean sperm parameters (concentration, motility, and morphology) than infertile men, there is significant overlap between fertile and infertile men [3]. Approximately 15% of infertile men have a normal spermiogram [4]. Hence routine semen analysis may describe some aspect of the function of testis and sperm but they do not address the functional competence of the sperm attributed DNA integrity.…”
Section: Introductionmentioning
confidence: 99%
“…Stimulated IUI cycles have considerably higher pregnancy rates (PR) than unstimulated cycles (1,2). In IUI cycles stimulated with gonadotropins, higher PR have been reported than in clomiphene stimulated cycles (3)(4)(5).…”
Section: Introductionmentioning
confidence: 99%