Efficacy of two extra-label anthelmintic formulations against equine strongyles in Cuba

Salas-Romero, Josmel; Gómez-Cabrera, Karel; Molento, Marcelo Beltrão; Lyons, E. T.; Delgado, Anay; González, Luis Gustavo Martínez; Arenal, Amílcar; Nielsen, Martin K.

doi:10.1016/j.vprsr.2017.01.010

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…An extra-label pellet formulation of ABZ licensed for ruminants and administered to horses at a dose of 7.5 mg kg −1 BW showed a reduced efficacy against small strongyles. However, considering that there are no precise indications on the evaluation of the formulation used, it is not possible to state the certain presence of AR (Salas-Romero et al ., 2017 ). ABZ suspension (25 mg mL −1 ) was administered in a single oral dose at 10 mg kg −1 BW and 2 oral doses 14 days apart at 10 mg kg −1 BW in donkeys and both doses showed high efficacy against adult stages of large and small strongyles until the end of the study period (Imam et al ., 2010 ).…”

Section: Anthelmintics In Horses and Donkeysmentioning

confidence: 99%

Horse and donkey parasitology: differences and analogies for a correct diagnostic and management of major helminth infections

et al. 2023

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In June 2022, at the XXXII Conference of the Italian Society of Parasitology, the parallels of the main endoparasitic infections of horses and donkeys were discussed. Although these 2 species are genetically different, they can be challenged by a similar range of parasites (i.e. small and large strongyles, and Parascaris spp.). Although equids can demonstrate some level of resilience to parasites, they have quite distinct helminth biodiversity, distribution and intensity among different geographical locations and breeds. Heavily infected donkeys may show fewer clinical signs than horses. Although parasite control is primarily provided to horses, we consider that there may be a risk of drug-resistance parasitic infection through passive infection in donkeys when sharing the same pasture areas. Knowing the possible lack of drug efficacy (<90 or 80%), it is advocated the use of selective treatment for both species based on fecal egg counts. Adult horses should receive treatment when the threshold exceeds 200–500 eggs per gram (EPG) of small strongyles. Moreover, considering that there are no precise indications in donkeys, a value >300 EPG may be a safe recommendation. We have highlighted the main points of the discussion including the dynamics of helminth infections between the 2 species.

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Section: Anthelmintics In Horses and Donkeysmentioning

confidence: 99%

Horse and donkey parasitology: differences and analogies for a correct diagnostic and management of major helminth infections

et al. 2023

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Eficacia de antiparasitarios orales en el tratamiento y control de nematodos gastrointestinales en equinos

Santillan

León-Gallardo

Gutiérrez

et al. 2021

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El estudio tuvo como objetivo determinar la eficacia de dos antiparasitarios orales en el control de nematodos gastrointestinales en equinos. Se utilizaron 45 yeguas de 2 a 4 años distribuidas aleatoriamente en tres grupos: I: grupo control, II: tratamiento con antiparasitario. doramectina en dosis de 11,4 mg/kg de peso vivo y III: tratamiento con antiparasitario fenbendazole en dosis de 7,5 mg /kg de peso vivo, con 15 repeticiones cada uno. Se colectaron muestras de heces previas a la dosificación y a los 30 días post tratamiento. Las muestras fecales fueron analizadas mediante la técnica de Baermann modificada en copa, Kato-Katz y la prueba de Graham. Los datos de pre y post tratamiento se analizaron con pruebas paramétricas y no paramétricas. La eficacia de los tratamientos se determinó mediante el método de porcentaje de reducción de huevos por gramo de heces (hpg). Todas las yeguas resultaron positivas a nematodos, identificándose Strongylus sp, Parascaris sp y Oxyuris sp. La eficacia de la doramectina fue de 97% y del fenbendazole 51% (p<0.05).

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Efficacy of two extra-label anthelmintic formulations against equine strongyles in Cuba

Cited by 2 publications

References 22 publications

Horse and donkey parasitology: differences and analogies for a correct diagnostic and management of major helminth infections

Horse and donkey parasitology: differences and analogies for a correct diagnostic and management of major helminth infections

Eficacia de antiparasitarios orales en el tratamiento y control de nematodos gastrointestinales en equinos

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