2020
DOI: 10.1038/s41598-020-63299-8
|View full text |Cite
|
Sign up to set email alerts
|

Efficacy of Ultrasound-guided Radiofrequency Ablation of Parathyroid Hyperplasia: Single Session vs. Two-Session for Effect on Hypocalcemia

Abstract: To evaluate safety and efficacy of one-vs. two-session radiofrequency ablation (RFA) of parathyroid hyperplasia for patients with secondary hyperparathyroidism (SHPT) and to compare the outcome of both methods on hypocalcemia. Patients with secondary hyperparathyroidism underwent ultrasound guided RFA of parathyroid hyperplasia. Patients were alternately assigned to either group 1 (n = 28) with RFA of all 4 glands in one session or group 2 (n = 28) with RFA of 2 glands in a first session and other 2 glands in … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
30
0

Year Published

2020
2020
2024
2024

Publication Types

Select...
5
3
2

Relationship

1
9

Authors

Journals

citations
Cited by 35 publications
(30 citation statements)
references
References 45 publications
(36 reference statements)
0
30
0
Order By: Relevance
“…As TPTX removes all four parathyroid glands to reduce the risk of secondary resection, ultrasound-guided MWA for SHPT completely inactivates the hyperplastic glands which can be displayed on ultrasound. Since the two surgical methods and treatment strategies are completely different, MWA sometimes requires multiple sessions to achieve the treatment purpose [23]; the level of PTH may fluctuate during the follow-up, resulting in postoperative serum calcium value fluctuation. Persistence and/or recurrence SHPT was more common in thermal ablation [9].…”
Section: Discussionmentioning
confidence: 99%
“…As TPTX removes all four parathyroid glands to reduce the risk of secondary resection, ultrasound-guided MWA for SHPT completely inactivates the hyperplastic glands which can be displayed on ultrasound. Since the two surgical methods and treatment strategies are completely different, MWA sometimes requires multiple sessions to achieve the treatment purpose [23]; the level of PTH may fluctuate during the follow-up, resulting in postoperative serum calcium value fluctuation. Persistence and/or recurrence SHPT was more common in thermal ablation [9].…”
Section: Discussionmentioning
confidence: 99%
“…US-guided RFA was performed using grey-scale imaging with a iU22 US scanner and a highfrequency linear probe (L12-5) (Philips, The Netherlands), while contrast-enhanced ultrasound (CEUS) with a high-frequency linear probe (L9-3) was used to monitor the RFA procedures ( Fig. 2A, 2D), as well as the initial diagnostic evaluation and the follow-up 11 . All patients were studied with US before the treatment by one of two radiologists (Kefei Cui and Yuanjing Huang) enrolled in the study, with 35 and 20 years of thyroid US experience, respectively.…”
Section: Methodsmentioning
confidence: 99%
“…Therefore, a less invasive therapeutic intervention with greater efficacy and shorter recovery period is required for patients with refractory SHPT. Radiofrequency ablation (RFA) is a minimally invasive, non-surgical procedure that increasingly being used to treat refractory hyperparathyroidism and achieve clinical affirmation [7,8] . However, no study so far has compared the clinical efficacy and safety of surgery and RFA for the treatment of refractory SHPT.…”
Section: Introductionmentioning
confidence: 99%