Efficacy of Vaccination against Infection with Velogenic Newcastle Disease Virus Genotypes VI and VII 1.1 Strains in Japanese Quails

Abd-Ellatieff, Hoda A.; Aziem, Alaa N. Abd El; Elbestawy, Ahmed R.; Goda, Wael; Belih, Soaad; Ellakany, Hany F.; El-Hamid, Hatem S. Abd; Yanai, Tokuma; Abou-Rawash, Abdel-Rahman; El‐Habashi, Nagwan

doi:10.1016/j.jcpa.2021.05.003

Cited by 6 publications

(5 citation statements)

References 48 publications

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“…The virus shedding in the control or vaccinated chickens was mostly noted during the first post-challenge days. These results were aligned with previous findings demonstrating the highest percentage of shedder birds on the third post-challenge days ( Sultan et al, 2020 ), and also were in agreement with the results showing the ability of mismatched vaccines to prevent virus transmission ( Abd-Ellatieff et al, 2021 ; Miller et al, 2013 ; Van Boven et al, 2008 ). However, Miller et al (2007) and Bello et al (2020) suggest that challenge vNDV matched vaccines significantly reduce oral shedding compared to mismatched vaccines.…”

Section: Discussionsupporting

confidence: 92%

“…This also may explain the observed longer survivability time and higher odds ratio for protection in La Sota and Colne12.IR compared to the B1 vaccinal strains. Studies have consistently shown genotype II-based vaccines confer high protection against virulent NDV genotype VII strains ( Abd-Ellatieff et al, 2021 ; Roohani et al, 2015 ; Mahmoud et al, 2019 ). Dewidar et al (2022) also demonstrated that the protection level in birds that received two doses of the La Sota live vaccine at 7 and 21 days of age was 93.3 % after the challenge, which was comparable to the group that received the genotype VII recombinant live vaccine.…”

Section: Discussionmentioning

confidence: 99%

“…Phylogenetic analysis of the fusion protein (F) gene sequence categorizes NDV strains into two classes: class I and class II ( Miller et al, 2013 ). Notably, within the class II NDVs, genotype VII strains have been pivotal in the fourth major panzootic of ND, widely circulating across Asia, Europe, the Middle East, and Africa, establishing themselves as one of the predominant and crucial global genotypes ( Abd-Ellatieff et al, 2021 ; Miller et al, 2015 ). Genotype VII NDV strains have been prevalent in Iranian poultry farms since 2011, emerging as the dominant circulating genotype in various avian species within the country ( Goudarzi et al, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the Newcastle disease virus genotype VII–mismatched vaccines in SPF chickens: A challenge efficacy study

Hassanzadeh,

Abedi,

Bashashati

et al. 2024

Veterinary and Animal Science

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of the Newcastle disease virus genotype VII–mismatched vaccines in SPF chickens: A challenge efficacy study

Hassanzadeh,

Abedi,

Bashashati

et al. 2024

Veterinary and Animal Science

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“…Vaccination using La-Sota vaccine strain has successfully protected the birds against the mortality caused by Newcastle disease and decreased expressiveness of the clinical signs, pathological changes and cloacal isolation of the virus (Abd-Ellatieff et al, 2021). Lentogenic La-Sota strain for the vaccination of newborn single day chickens provided protection of broiler chickens throughout the life cycle (Cvetić et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

Immunological evaluation of inactivated Newcastle disease vaccine depending on adjuvant composition

Chegrynets

Saliy

Sobko

et al. 2021

Regul. Mech. Biosyst.

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Newcastle disease is a global problem that is being recorded in most countries and also a serious obstacle to exchange of genetic material of poultry in various countries of the world. Control of the Newcastle disease comprises correct injection of efficacious vaccines so as to decrease or eliminate the clinical disease. Our goal was to perform comparative studies of the vaccines against Newcastle disease of water in oil type, the adjuvant being mineral oil mixed with emulsifiers (Span-80 and Tween-80) and ready-to-use adjuvant system (Montanide ISA 70), and study the impact of composition of adjuvant constituent on physical-chemical and immunogenic properties of inactivated vaccines. To reproduce virus-containing material and carried out titration of the viruses, we used chicken embryos free of pathogenic microflora. Aqueous phase for the preparation of emulsion-based vaccines of water in oil type consisted of antigen to Newcastle disease of La-Sota strain, manufactured by Biotestlab Ltd, and phosphate-saline buffer. To evaluate the effectiveness of the vaccine and induce immune response, we used 1-day old pathogen-free chickens, which were obtained from chicken embryos free of pathogenic microflora. As the positive control in the experiment, we used commercial vaccine. One-day chickens were divided into 3 groups (I, II, III) comprising 12 individuals each and one group (IV) consisting of 8 individuals as the control group with individual numeration. Chickens in groups I, II and III were divided into two subgroups (n = 8 and n = 4) to determine immunogenic efficiency and safety of the vaccine. Immunization was carried out through single subcutaneous injections in the region of the neck. To study immunogenic efficiency, the chickens were immunized with the dose of 0.1 mL (1 dose), and 0.2 mL (2 doses) to determine safety. After the immunization of 1-day old pathogen-free chickens with 0.1 mL dose, the obtained level of antibodies in the serum of vaccinated chickens on days 14, 21, 28, 35 and 42 after the vaccination indicated the ability of provoking the immune response to Newcastle disease at high level and safety of the vaccination for chickens. All the recipes of the examined series of the vaccines and the commercial vaccine produced appropriate level of viscosity according to the criterion equaling ≤ 200 mm2/s at Р <0.05, promoting fluidity of the vaccine and providing easier passage through the needle during the application. Both of the studied vaccines may be used in poultry farming for prophylaxis of Newcastle disease among chickens.

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“…However, class II includes virulent and non-virulent strains and consists of at least 20 genotypes (I-XXI) and multiple sub-genotypes following the exclusion of genotype XV, which contains recombinant sequences [5,6]. Genotype VII.1.1 of NDV is now regarded as the predominant circulating genotype in various poultry species in Egypt, as well as several African, Middle East, Asian, and European countries [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Superior Efficacy of Apathogenic Genotype I (V4) over Lentogenic Genotype II (LaSota) Live Vaccines against Newcastle Disease Virus Genotype VII.1.1 in Pathogen-Associated Molecular Pattern-H9N2 Vaccinated Broiler Chickens

Elbestawy,

Ellakany,

Sedeik

et al. 2023

Vaccines

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A comparison of the efficacy of apathogenic genotype I (V4) and lentogenic genotype II (LaSota) strains of live Newcastle disease virus (NDV) vaccines was performed following vaccination with pathogen-associated molecular pattern (PAMP) H9N2 avian influenza vaccine and challenge with velogenic NDV genotype VII.1.1 (vNDV-VII.1.1). Eight groups (Gs) of day-old chicks were used (n = 25). Groups 1–4 received a single dose of PAMP-H9N2 subcutaneously, while Gs (1, 5) and (2, 6) received eye drops of V4 and LaSota, respectively, as two doses. All Gs, except for 4 and 8, were intramuscularly challenged with vNDV-VII.1.1 at 28 days of age. No signs were detected in Gs 1, 5, 4, and 8. The mortality rates were 0% in Gs 1, 4, 5, and 8; 40% in G2; 46.66% in G6; and 100% in Gs 3 and 7. Lesions were recorded as minimal in Gs 1 and 5, but mild to moderate in Gs 2 and 6. The lowest significant viral shedding was detected in Gs 1, 2, and 5. In conclusion, two successive vaccinations of broilers with a live V4 NDV vaccine provided higher protection against vNDV-VII.1.1 challenge than LaSota. PAMP-H9N2 with live NDV vaccines induced more protection than the live vaccine alone.

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Efficacy of Vaccination against Infection with Velogenic Newcastle Disease Virus Genotypes VI and VII 1.1 Strains in Japanese Quails

Cited by 6 publications

References 48 publications

Evaluation of the Newcastle disease virus genotype VII–mismatched vaccines in SPF chickens: A challenge efficacy study

Evaluation of the Newcastle disease virus genotype VII–mismatched vaccines in SPF chickens: A challenge efficacy study

Immunological evaluation of inactivated Newcastle disease vaccine depending on adjuvant composition

Superior Efficacy of Apathogenic Genotype I (V4) over Lentogenic Genotype II (LaSota) Live Vaccines against Newcastle Disease Virus Genotype VII.1.1 in Pathogen-Associated Molecular Pattern-H9N2 Vaccinated Broiler Chickens

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