Efficacy of WeChat-based online smoking cessation intervention (‘WeChat WeQuit’) in China: a randomised controlled trial

Tang, Jinsong; Yang, Jie; Liu, Yi; Liu, Xiaocong; Li, Ling; Sun, Yuan; Jin, Jiyuan; Fang, Yehong; Zitang, Zhou,; Wang, Yunfei; Liu, Yueheng; Chen, Wei; McNeill, Ann; Kelly, Brian C.; Cohen, Joanna E.; Liao, Yanhui

doi:10.1016/j.eclinm.2023.102009

Cited by 16 publications

(3 citation statements)

References 34 publications

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“…Compared with previous studies involving IM-based interventions [ 7 - 10 , 13 ], we have enhanced our approach by developing 3 sets of messages tailored to the planned quit date. Additionally, we have personalized the messages based on participants’ sociodemographic characteristics and smoking behaviors.…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, we have personalized the messages based on participants’ sociodemographic characteristics and smoking behaviors. In contrast to previous studies where the control group typically received minimal treatment [ 7 , 10 , 13 ], we took a proactive approach by referring all participants in this study to free and effective local SC services. This design was chosen because AR is locally recommended, such as through an online training course funded by the Department of Health for general practitioners, backed by evidence from our prior trials in community smokers [ 29 - 31 ].…”

Section: Discussionmentioning

confidence: 99%

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Effect of Adding Personalized Instant Messaging Apps to a Brief Smoking Cessation Model in Community Smokers in Hong Kong: Pragmatic Randomized Clinical Trial

Wu,

Cheung,

Lee

et al. 2024

J Med Internet Res

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Background While text messaging has proven effective for smoking cessation (SC), engagement in the intervention remains suboptimal. Objective This study aims to evaluate whether using more interactive and adaptive instant messaging (IM) apps on smartphones, which enable personalization and chatting with SC advisors, can enhance SC outcomes beyond the provision of brief SC advice and active referral (AR) to SC services. Methods From December 2018 to November 2019, we proactively recruited 700 adult Chinese daily cigarette users in Hong Kong. Participants were randomized in a 1:1 ratio. At baseline, all participants received face-to-face brief advice on SC. Additionally, they were introduced to local SC services and assisted in selecting one. The intervention group received an additional 26 personalized regular messages and access to interactive chatting through IM apps for 3 months. The regular messages aimed to enhance self-efficacy, social support, and behavioral capacity for quitting, as well as to clarify outcome expectations related to cessation. We developed 3 sets of messages tailored to the planned quit date (within 30 days, 60 days, and undecided). Participants in the intervention group could initiate chatting with SC advisors on IM themselves or through prompts from regular messages or proactive inquiries from SC advisors. The control group received 26 SMS text messages focusing on general health. The primary outcomes were smoking abstinence validated by carbon monoxide levels of <4 parts per million at 6 and 12 months after the start of the intervention. Results Of the participants, 505/700 (72.1%) were male, and 450/648 (69.4%) were aged 40 or above. Planning to quit within 30 days was reported by 500/648 (77.2%) participants, with fewer intervention group members (124/332, 37.3%) reporting previous quit attempts compared with the control group (152/335, 45.4%; P=.04). At the 6- and 12-month follow-ups (with retention rates of 456/700, 65.1%, and 446/700, 63.7%, respectively), validated abstinence rates were comparable between the intervention (14/350, 4.0%, and 19/350, 5.4%) and control (11/350, 3.1% and 21/350, 6.0%) groups. Compared with the control group, the intervention group reported greater utilization of SC services at 12 months (RR 1.26, 95% CI 1.01-1.56). Within the intervention group, engaging in chat sessions with SC advisors predicted better validated abstinence at 6 months (RR 3.29, 95% CI 1.13-9.63) and any use of SC services (RR 1.66, 95% CI 1.14-2.43 at 6 months; RR 1.67, 95% CI 1.26-2.23 at 12 months). Conclusions An IM-based intervention, providing support and assistance alongside brief SC advice and AR, did not yield further increases in quitting rates but did encourage the utilization of SC services. Future research could explore whether enhanced SC service utilization leads to improved long-term SC outcomes. Trial Registration ClinicalTrials.gov NCT03800719; https://clinicaltrials.gov/ct2/show/NCT03800719

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effect of Adding Personalized Instant Messaging Apps to a Brief Smoking Cessation Model in Community Smokers in Hong Kong: Pragmatic Randomized Clinical Trial

Wu,

Cheung,

Lee

et al. 2024

J Med Internet Res

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“…Smoking/Drinking craving will be measured with the Visual Analogue Scale (VAS) and the Penn Alcohol Craving Scale (for smoking, with replacement of “alcohol” by “smoking”) [ 50 ]. Self-reported smoking or alcohol consumption uses the past seven days as reference period.…”

Section: Methodsmentioning

confidence: 99%

Effectiveness of a socioecological model-guided, smart device-based, self-management-oriented lifestyle intervention in community residents: protocol for a cluster-randomized controlled trial

Yang,

Yu,

Liao

et al. 2024

BMC Public Health

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Background Healthy lifestyles are crucial for preventing chronic diseases. Nonetheless, approximately 90% of Chinese community residents regularly engage in at least one unhealthy lifestyle. Mobile smart devices-based health interventions (mHealth) that incorporate theoretical frameworks regarding behavioral change in interaction with the environment may provide an appealing and cost-effective approach for promoting sustainable adaptations of healthier lifestyles. We designed a randomized controlled trial (RCT) to evaluate the effectiveness of a socioecological model-guided, smart device-based, and self-management-oriented lifestyles (3SLIFE) intervention, to promote healthy lifestyles among Chinese community residents. Methods This two-arm, parallel, cluster-RCT with a 6-month intervention and 6-month follow-up period foresees to randomize a total of 20 communities/villages from 4 townships in a 1:1 ratio to either intervention or control. Within these communities, a total of at least 256 community residents will be enrolled. The experimental group will receive a multi-level intervention based on the socioecological model supplemented with a multi-dimensional empowerment approach. The control group will receive information only. The primary outcome is the reduction of modifiable unhealthy lifestyles at six months, including smoking, excess alcohol consumption, physical inactivity, unbalanced diet, and overweight/obesity. A reduction by one unhealthy behavior measured with the Healthy Lifestyle Index Score (HLIS) will be considered favorable. Secondary outcomes include reduction of specific unhealthy lifestyles at 3 months, 9 months, and 12 months, and mental health outcomes such as depression measured with PHQ-9, social outcomes such as social support measured with the modified Multidimensional Scale of Perceived Social Support, clinical outcomes such as obesity, and biomedical outcomes such as the development of gut microbiota. Data will be analyzed with mixed effects generalized linear models with family and link function determined by outcome distribution and accounting for clustering of participants in communities. Discussion This study will provide evidence concerning the effect of a mHealth intervention that incorporates a behavioral change theoretical framework on cultivating and maintaining healthy lifestyles in community residents. The study will provide insights into research on and application of similar mHealth intervention strategies to promote healthy lifestyles in community populations and settings. Trial registration number ChiCTR2300070575. Date of registration: April 17, 2023. https://www.chictr.org.cn/index.aspx.

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Pharmacist-Led Management Model and Medication Adherence Among Patients With Chronic Heart Failure

Wang,

Zhao,

Han

et al. 2024

JAMA Netw Open

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ImportancePoor medication adherence is associated with high morbidity and mortality among patients with chronic heart failure (CHF), which is particularly concerning in China.ObjectiveTo assess the effect of a pharmacist-led management model incorporating a social media platform vs usual care on medication adherence in patients with CHF.Design, Setting, and ParticipantsThis prospective, multicenter randomized clinical trial was conducted from March 2021 to May 2023, with a follow-up duration of 52 weeks. The trial was conducted in the cardiology wards of 5 hospitals in China. Participants were 18 years or older, had a CHF diagnosis, and were receiving stable medication. They were randomly assigned to either the intervention group (pharmacist-led management) or the control group (usual care) in a 1:1 ratio using a computer-generated random number table with concealed allocation via opaque envelopes. Intention-to-treat data analysis was performed from June 2023 to July 2024.InterventionThe intervention group received a multimodal pharmaceutical intervention, including WeChat application–based communication and education, and a standardized follow-up visit from a pharmacist every month. The control group received the standardized follow-up visit from nurses every month.Main Outcomes and MeasuresThe primary outcome was the proportion of days covered (PDC) by heart failure medication at 52 weeks.ResultsAmong the 445 participants analyzed, 223 were assigned to the intervention group and 222 to the control group. These patients had a mean (SD) age of 63.2 (13.3) years and included 263 males (59.1%). A total of 333 patients (74.8%) had a New York Heart Association class III or IV heart failure, indicating severe limitations in physical activity. At 52 weeks, the intervention group had a significantly higher PDC for heart failure medication (8.1%; 95% CI, 5.5%-10.7%; P &lt; .001) and a greater proportion of patients with PDC of 80% or greater (odds ratio, 0.34; 95% CI, 0.21-0.54; P &lt; .001) compared with the control group.Conclusions and RelevanceThis randomized clinical trial found a modest improvement in medication adherence among patients with CHF who received the pharmacist-led management intervention vs usual care.Trial RegistrationChinese Clinical Trial Registry Identifier: ChiCTR2000040232

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Efficacy of WeChat-based online smoking cessation intervention (‘WeChat WeQuit’) in China: a randomised controlled trial

Cited by 16 publications

References 34 publications

Effect of Adding Personalized Instant Messaging Apps to a Brief Smoking Cessation Model in Community Smokers in Hong Kong: Pragmatic Randomized Clinical Trial

Effect of Adding Personalized Instant Messaging Apps to a Brief Smoking Cessation Model in Community Smokers in Hong Kong: Pragmatic Randomized Clinical Trial

Effectiveness of a socioecological model-guided, smart device-based, self-management-oriented lifestyle intervention in community residents: protocol for a cluster-randomized controlled trial

Pharmacist-Led Management Model and Medication Adherence Among Patients With Chronic Heart Failure

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