2014
DOI: 10.1158/1535-7163.mct-13-0819
|View full text |Cite
|
Sign up to set email alerts
|

Efficacy of Zibotentan in Colorectal Cancer—Letter

Abstract: In their study, Haque and colleagues evaluate the specific endothelin A receptor (ETAR) antagonist zibotentan in colorectal cancer cellular models with relevance to proliferation and migration potential of tumor cells and stromal fibroblasts. Interestingly, they demonstrate that ETAR is the principal receptor used by ET-1 and provide evidence for involvement of stromal fibroblasts in cancer progression as targets of ET-1 signaling. Given zibotentan had the greatest inhibitory effect on ET-1 signaling, the auth… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 7 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?