Efficacy of Zinc Sulfate as an Add-on Therapy to Risperidone versus Risperidone Alone in Patients With Schizophrenia: A Double-Blind Randomized Placebo-Controlled Trial

Purpose: Unhealthy lifestyle factors make up a significant proportion of the factors that cause high morbidity and mortality risk. The life span of patients with schizophrenia is 10–20 years less than that of the general population due to lifestyle-related diseases. The aim of this study is to compare with healthy individuals the nutritional habits, nutritional status, and physical activity levels of schizophrenic patients. Materials and Methods: The study was conducted on 25–55-year-old 40 patients diagnosed with schizophrenia or schizoaffective disorders and 30 healthy controls matched for age and gender. Data on sociodemographic characteristics and nutritional habits, three-day food consumption and a 24-hour retrospective physical activity records were collected. Results: Dietary energy, protein, total fat, cholesterol, and fiber intakes were found to be lower only in female schizophrenia patients than in their healthy counterparts. Patients with schizophrenia presented with lower intakes of dietary thiamine, niacin, iron, and zinc compared to healthy controls. Patients with schizophrenia recorded lower physical activity levels compared to healthy controls (1.59±0.22 and 1.77±0.17 respectively ). Conclusion: Unhealthy diet and sedentary life observed in patients with schizophrenia can lead to the development of serious medical comorbidities and to an increase in the side effects of antipsychotic medications. Therefore, patients with schizophrenia should be encouraged to consume healthy diets and undertake more physical activities requires the multidisciplinary approach of specialized professionals.

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Crime and Nourishment: A Narrative Review Examining Ultra-Processed Foods, Brain, and Behavior

Prescott,

Logan,

LaFata

et al. 2024

Dietetics

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Recently, there has been increased scientific and clinical interest in the potential harms associated with ultra-processed foods, including poor mental health, aggression, and antisocial behavior. Research spanning epidemiology, mechanistic pre-clinical work, addiction science, microbiome and exposome science, and human intervention trials has underscored that nutrition is of relevance along the criminal justice continuum. As such, the emerging dietetics research is salient to the thousands of international psychologists and allied mental health professionals that are engaged in justice work, including forensics, prevention, and intervention. In addition, relationships between nutrition and behavior relate to “food crime”, an emergent area unifying criminal justice researchers with psychology, public health, and other interdisciplinary sectors. Food crime scrutinizes the vast harms, including non-communicable diseases and adverse behavioral outcomes, as influenced by the distribution of addictive ultra-processed food products. Here, we examine the emergent research, including biophysiological mechanisms, and evidence indicating that dietary patterns/components intersect with psychosocial vulnerabilities linked with risks of antisocial behavior and justice involvement. Viewed through a prevention lens, the study of nutrition and aggressive behavior should be prioritized, especially if the outcomes emerge as externalities of the global consumption of ultra-processed food. In the context of criminal justice and behavior, there is a need for forensic examination of how industry influence and power structures can undermine matters of food justice.

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Efficacy of Zinc Sulfate as an Add-on Therapy to Risperidone versus Risperidone Alone in Patients With Schizophrenia: A Double-Blind Randomized Placebo-Controlled Trial

Cited by 4 publications

References 43 publications

Diet and Psychosis

Diet and Psychosis

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Crime and Nourishment: A Narrative Review Examining Ultra-Processed Foods, Brain, and Behavior

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