Efficacy, safety and feasibility of ultrasound‐guided percutaneous microwave ablation for large hepatic hemangioma

Abstract

OBJECTIVE:To evaluate the efficacy, safety and feasibility of microwave ablation (MWA) for large (5-10 cm in diameter) hepatic hemangioma. METHODS:In all, 46 patients with 47 large hepatic hemangiomas were treated with ultrasound-guided percutaneous MWA. The effect of MWA for all patients was evaluated by enhanced magnetic resonance imaging or computed tomography within two months after ablation. RESULTS:A total of 27 male and 19 female patients were enrolled, with an average age of 46 ± 11 years. The average size of hemangiomas was 6.3 ± 1.4 cm (range 5.0-9.6 cm). The initial complete ablation rate was 91.5% (43/47) and the volume of ablated lesions was significantly reduced. The rate of complete necrosis was not associated with the tumor size or location (P = 0.899 and 0.758, respectively). The total complete ablation rate was 95.7% (45/47). Major complications included acute renal dysfunction, hyperbilirubinemia and pleural effusion. No procedure-related death occurred. The average hospitalization stay was 5.7 ± 2.5 days (range 3-17 days). During a follow-up period of 18.2 months (range 4-40 months), one patient developed local tumor progression at the radiofrequency ablation site. Three patients had new hemangiomas in other sites of the liver. At the end of the study all patients were alive and no severe complications occurred. CONCLUSION:Image-guided MWA is an effective and safe treatment for large hepatic hemangiomas, and can potentially be regarded as the first-line therapy.

Feasibility, safety, and efficacy of ultrasound-guided percutaneous microwave ablation for giant hepatic hemangioma

“…Thus, complete ablation for hemangiomas near a 'high-risk location' is possible. This conclusion was consistent with the results of RFA for hepatic hemangioma in previous studies [26][27][28][29].…”

“…MWA achieved a 95.7% complete ablation rate, 10.9% severe complication rate, and a shorter ablation time than did RFA. Therefore, we inferred that MWA was suitable for giant hepatic hemangiomas [26] and tried to apply MWA to 12 patients with 13 giant hepatic hemangiomas (!10 cm) in this study.…”

Safety and effective of laparoscopic microwave ablation for giant hepatic hemangioma: A retrospective cohort study

“…We do not choose a percutaneous approach to ablate the hemangiomas under the guidance ultrasound as the follow reasons. First, when then lesion located in subcapsular or near-gallbladder areas, there is a risk of damage to adjacent tissues [28,29]. Second, When there is a small amount of bleeding, the ultrasound is not easy to find in time.…”

Ultrasound-Guided Microwave Ablation of Fast-Growing Small-Sized Hepatic Hemangiomas

“…Противопоказанием к эмболизации гемангиомы печени является ее близкое расположение к желчному пузырю, так как в процесс может быть вовлечена пузырная артерия, что может повлечь развитие острого холецитиста. Описаны такие осложнения при эмболизации гемангиом, как желчный перитонит вследствие деструкции стенки желчного пузыря, печеночная недостаточность из-за массивной ишемии участков паренхимы печени [14,15]. У 5 из 11 пациентов гемангиомы печени после эмболизации уменьшились в объеме, признаков васкуляризации не было.…”