Efficacy, safety, and flap dimensions of a new femtosecond laser for laser in situ keratomileusis

Vryghem, Jérôme C; Devogelaere, Thibaut; Stodůlka, Pavel

doi:10.1016/j.jcrs.2009.09.030

Cited by 33 publications

(14 citation statements)

References 16 publications

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“…A study reported that flap dimensions and refractive results of LASIK using the Femto LDV were predictable, with an acceptable rate of complications and that no eyes had significant losses in CDVA at 6 months postop 28. Likewise, the predictability and accuracy of the IntraLase for flap creation, when compared to a microkeratome, were reported 29.…”

Section: Discussionmentioning

confidence: 99%

Comparison of DLK incidence after laser in situ keratomileusis associated with two femtosecond lasers: Femto LDV and IntraLase FS60

Tomita

Sotoyama²,

Yukawa³

et al. 2013

OPTH

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PurposeTo compare the incidence of diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK) with flap creation using the Femto LDV and IntraLase™ FS60 femtosecond lasers.0MethodsA total of 818 consecutive myopic eyes had LASIK performed using either Femto LDV or IntraLase FS60 for flap creation. The same excimer laser, the Allegretto Wave® Eye-Q Laser, was used for correcting refractive errors for all patients. In the preoperative examination, uncorrected distance visual acuity, corrected distance visual acuity, and manifest refraction spherical equivalent were measured. At the postop examination, the same examinations were performed along with a slit-lamp biomicroscopic examination, and patients with DLK were classified into stages. For the statistical analysis of the DLK occurrence rate and the visual and refractive outcomes, the Mann-Whitney’s U-test was used.ResultsIn the Femto LDV group with 514 eyes, 42 (8.17%) had DLK. In the IntraLase FS60 group with 304 eyes, 114 (37.5%) had DLK. There was a statistically significant difference in the DLK incidence rate between these groups (P < 0.0001). Both groups had excellent visual and refractive outcomes. Although low levels of DLK were observed for both groups, they did not affect visual acuity.ConclusionWhile there were significantly fewer incidences of low level DLK when using Femto LDV, neither femtosecond laser induced high levels of DLK, and any postoperative DLK cleared up within 1 week. Therefore, both lasers provide excellent results, with no clinical differences, and both excel at flap creation for LASIK.

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Section: Discussionmentioning

confidence: 99%

Comparison of DLK incidence after laser in situ keratomileusis associated with two femtosecond lasers: Femto LDV and IntraLase FS60

Tomita

Sotoyama²,

Yukawa³

et al. 2013

OPTH

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“…Similar findings were reported in other studies. [30][31][32] Table 3 shows the complications in other studies using the VisuMax or another femtosecond laser platform. 14,18,27,[31][32][33][34] Most of these studies were performed during the learning phase of the procedure, and the rate of complications will decline gradually over time.…”

Section: Discussionmentioning

confidence: 99%

Femtosecond laser flap parameters and visual outcomes in laser in situ keratomileusis

Issa¹,

Hassany²

2011

Journal of Cataract and Refractive Surgery

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“…Current ANSI laser safety standards for femtosecond NIR pulses cover accidental exposures of the eye and skin to pulsed irradiation in terms of immediate damage, rather than a systematic planned exposure of tissue and any resulting long term effects. The research literature contains limited reports on the safety of NIR ultrashort laser pulses in humans, with the majority being related to the use of femtosecond laser pulses in the eye (e.g [14]. ) due to the increased use of femtosecond ablation in Lasik surgery.…”

Section: Introductionmentioning

confidence: 99%

Feasibility of using multiphoton excited tissue autofluorescence for in vivo human histopathology

Cruz

McMullen

Williams

et al. 2010

Biomed. Opt. Express

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Rapid and direct imaging of microscopic tissue morphology and pathology can be achieved by multiphoton imaging of intrinsic tissue fluorophores and second harmonic signals. Engineering parameters for developing this technology for clinical applications include excitation levels and collection efficiencies required to obtain diagnostic quality images from different tissue types and whether these levels are mutagenic. Here we provide data on typical average powers required for high signal-to-noise in vivo tissue imaging and assess the risk potential of these irradiance levels using a mammalian cell gene mutation assay. Exposure times of ~16 milliseconds per cell to 760 nm, ~200 fs raster-scanned laser irradiation delivered through a 0.75 NA objective produced negligible mutagenicity at powers up to about 50 mW.

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Efficacy, safety, and flap dimensions of a new femtosecond laser for laser in situ keratomileusis

Abstract: Overall, the flap dimensions and refractive results were predictable and the complication rate was acceptable after LASIK using the new femtosecond laser for flap creation.

Cited by 33 publications

References 16 publications

Comparison of DLK incidence after laser in situ keratomileusis associated with two femtosecond lasers: Femto LDV and IntraLase FS60

Comparison of DLK incidence after laser in situ keratomileusis associated with two femtosecond lasers: Femto LDV and IntraLase FS60

Femtosecond laser flap parameters and visual outcomes in laser in situ keratomileusis

Feasibility of using multiphoton excited tissue autofluorescence for in vivo human histopathology

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