2023
DOI: 10.21203/rs.3.rs-2431222/v1
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Efficacy, safety, and tolerability of antimicrobial agents for complicated intra- abdominal infection: a systematic review and network meta-analysis

Abstract: Background Which antimicrobial agents provide the optimal efficacy, safety, and tolerability for the empirical treatment of complicated intra-abdominal infection (cIAI) remains unclear but is paramount in the context of evolving antimicrobial resistance. Therefore, updated meta-analyses on this issue are warranted. Methods We systematically searched 4 major electronic databases from their inception through October 2022. Randomized controlled trials examining antimicrobial agents for cIAIs treatment were incl… Show more

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