Efficiency evaluation of innovative herbal compositions with inulin

Abstract

This work examines the issues of obtaining compositions with adaptogenic and prebiotic effects, quality control, as well as assessment of their biological effects. Inulin was analyzed by reverse-phase HPLC with refractometric detection. In vivo studies were performed using 50 male Wistar rats, 6 weeks old, with an initial body weight of 158 ± 3 g. To study the intestinal microbiota, DNA was extracted using the DNA-Sorb-S kit. As a result, compositions have been developed that include functional food ingredients based on spinach leaves and quinoa grains, containing at least 96.0% inulin. The established beneficial effect of adaptogenic compositions with inulin on the intestinal microbiota opens up the potential for their use to maintain the optimal composition of the intestinal microbiota.